HUGO ID Detailed Result 4235


HUGO ID 4235
Symbol GFAP
Name glial fibrillary acidic protein
#Occurrence 95
#Paper 22

 


PMID Match String Actual String Score Flanking text Edited by Edit
12843244GFAPGFAP2.5compared the numbers of microglia and astrocytes using MacI and GFAP as their respective markers in the spinal cords of caspase-11 
12843244GFAPGFAP-positive2.5showed dramatic increases in the number of MacI-positive microglia and GFAP-positive astrocytes with no significant differences in the absence or presence 
14511332GFAPGFAP2.5antibody to glial fibrillary acidic protein to label astrocytes (GFAP; GFAP DAKO Glostrup Denmark and a mouse monoclonal antihuman antibody to 
14511332GFAPGFAP2.5cells counterstaining with an antibody raised against the astrocyte marker GFAP was performed 
14511332GFAPGFAP2.5As demonstrated by the coexpression with GFAP glial COX-2 expression was predominantly found in astrocytes ( Fig 
14511332GFAPGFAP2.5ALS amyotrophic lateral sclerosis COX cyclooxygenase CSF cerebrospinal fluid GFAP glial fibrillary acidic protein IR immunoreactivity PG prostaglandins SOD superoxide 
15210305GFAPGFAP0.6GFAP up-regulation is not uncommonly seen in expression studies reflecting reactive 
15572176GFAPGFAP2.5processes with increased content of glial fibrillary acidic protein (GFAP) GFAP 
15572176GFAPGFAP2.5Reactive astrocytes in ALS show increased immunoreactivity for GFAP and the calcium binding protein S100_amp_#x3b2 85 and express inflammatory 
15572176GFAPGFAP2.5G86R SOD-1 mutation in astroglia under the control of a GFAP promoter failed to induce motor neuron loss and disease 52 
15572176GFAPGFAP2.5number of astrocytes 95 and 111 and the upregulation of GFAP and calcium-binding protein S100_amp_#x3b2 expression 138 
15572176GFAPGFAP2.5in motor neurons and increased number of process-bearing astrocytes over-expressing GFAP in the anterior horn 28 
15572176GFAPGFAP2.5changes characterized by the appearance of process-bearing cells displaying intense GFAP iNOS and nitrotyrosine immunoreactivity 19 and 20 
15572176GFAPGFAP2.5This is followed by a sustained increase in GFAP synthesis lasting for several days 129 
15649489GFAPGFAP2.5reduced gliosis as assessed by immunohistochemical staining for CD-40 and GFAP 
15649489GFAPGFAP2.5The sections were immunostained with CD40 (Serotec), Serotec GFAP (DAKO), DAKO iNOS (Upstate, Upstate Waltham MA NF_amp_#x3ba B (Santa 
15649489GFAPGFAP2.5immunoreactivity to the microglial marker CD40 and the astrocyte marker GFAP at 110 days of age 
15649489GFAPGFAP2.5Both CD40 and GFAP immunoreactivities were decreased in pioglitazone-treated G93A mice as compared to 
15649489GFAPGFAP2.5Pioglitazone treatment reduced CD40 (marker marker of microglial activation and GFAP (marker marker of astrocytosis immunoreactivity in the ventral horn of 
15657392GFAPGFAP2.5paper AChR acetylcholine receptor ALS amyotrophic lateral sclerosis CnA calcineurin GFAP glial fibrillary acidic protein Igf insulin-like growth factor mIgf-1 local 
15657392GFAPGFAP2.5(b) b Immunofluorescence analysis identify GFAP positive astrocytes in ventral horn of SOD1 and SOD1 /mIgf-1 
15657392GFAPGFAP2.5The intensity of the GFAP signal revealed progressive astrocytosis 
15657392GFAPGFAP2.5Insert in D shows Western blot for GFAP in the spinal cord of SOD1 (lanes lanes 1 and 
15657392GFAPGFAP2.5Comparable patterns of glial fibrillary acidic protein (GFAP) GFAP immunoreactivity were found in spinal cords of SOD1 ( n 
15657392GFAPGFAP2.5activation ( Fig 5 b C with an increase in GFAP expression of ~55 _amp_#177 0.2% ( Fig 5 b D 
15657392GFAPGFAP2.5Fig 5 b D insert lane 3 compared with the GFAP expression levels displayed in the spinal cord of age matched 
15657392GFAPGFAP2.5At comparable end-stage disease there were no significant differences in GFAP expression between SOD1 and SOD1 /mIgf-1 mIgf-1 mice although SOD1 
15657392GFAPGFAP2.5mIgf-1 mice although SOD1 mice continued to express 13% more GFAP as compared with SOD1 /mIgf-1 mIgf-1 mice (unpublished unpublished data 
15657392GFAPGFAP2.5(from from C Klee National Institutes of Health Bethesda MD GFAP 
15657392GFAPGFAP2.5(from from S Schiaffino University of Padova Padova Italy Agrin GFAP 
16014720GFAPGFAP2.5Vision Fremont CA rabbit polyclonal anti-glial fibrillary acidic protein (GFAP; GFAP 1 500 Chemicon Temecula CA mouse monoclonal anti-MAC-1 (1:1000; 1 
16014720GFAPGFAP2.5that ventral midbrain MPO-positive structures ( E red are also GFAP positive ( F green as evidenced by the overlay of 
16014720GFAPGFAP2.5tissue from PD patients compared with controls as well as GFAP tissue content 
16014720GFAPGFAP2.5This analysis confirmed that MPO colocalized with the astrocytic marker GFAP as shown by the merged image from the two fluorochromes 
16014720GFAPGFAP2.5the motor cortex from ALS patients did not exhibit higher GFAP or MPO values (data data not shown 
16014720GFAPGFAP2.5caudate nucleus tissues from stage 4 HD patients had higher GFAP to beta-actin ratios (HD, HD 0.7 _amp_#177 0.1 vs controls 
16179515GFAPGFAP2.5the G93A/SOD1 G93A SOD1 mutation glial fibrillary acidic protein (GFAP), GFAP stroma-derived factor-1 (SDF-1), SDF-1 and excitatory amino acid transporter-2 (EAAT2) 
16436205GFAPGFAP2.5to identify microglia and rhodamine-conjugated rabbit anti-glial fibrillary protein (GFAP) GFAP antibody (Chemicon) Chemicon to identify astroctyes 
16436205GFAPGFAP2.5based on immunocytochemical staining with anti-glial fibrillary acidic protein (GFAP) GFAP (not not illustrated 
16510725GFAPGFAP2.5(Serotec, Serotec Oxford UK and glial fibrillary acid protein (GFAP; GFAP Dako Carpinteria CA using a modified avidin-biotin peroxidase technique 
16510725GFAPGFAP2.5of age as demonstrated by colocalization with the astrocyte marker GFAP by double immunofluorescence ( Fig 1 
16510725GFAPGFAP2.5Double labeling of TNF-alpha with GFAP confirmed expression of TNF-alpha in astrocytes ( Fig 1 
16510725GFAPGFAP2.5TNF-alpha double immunofluorescence with GFAP showed that TNF-alpha colocalizes with GFAP in astrocytes 
16510725GFAPGFAP2.5TNF-alpha double immunofluorescence with GFAP showed that TNF-alpha colocalizes with GFAP in astrocytes 
16510725GFAPGFAP2.5points to an astrocyte labeled with TNF-alpha (green) green and GFAP (red) red and colocalization of TNF-alpha and GFAP (yellow) yellow 
16510725GFAPGFAP2.5green and GFAP (red) red and colocalization of TNF-alpha and GFAP (yellow) yellow 
16510725GFAPGFAP2.5FasL double immunofluorescence with GFAP showed that FasL colocalizes with GFAP in astrocytes 
16510725GFAPGFAP2.5FasL double immunofluorescence with GFAP showed that FasL colocalizes with GFAP in astrocytes 
16510725GFAPGFAP2.5arrows point to astrocytes labeled with FasL (green) green and GFAP (red) red and colocalization of FasL and GFAP (yellow) yellow 
16510725GFAPGFAP2.5green and GFAP (red) red and colocalization of FasL and GFAP (yellow) yellow 
16510725GFAPGFAP2.5immunoreactivity in astrocytes by double labeling with the astrocyte marker GFAP 
16510725GFAPGFAP2.5FasL immunoreactivity colocalized with GFAP indicating that FasL immunostaining was found in both neurons and 
16737688GFAPGFAP-2.5For analysis of gliosis the staining intensity in GFAP- and PT66-immunostained sections and the number of CD3- CD11c- and 
16737688GFAPGFAP2.5(A, A B or immunostained for SOD1 (C, C D GFAP (E, E F and PT66 (G, G H 
16737688GFAPGFAP2.5Immunostainings for GFAP and PT66 show abundant reactive astrocytes and microglial cells at 
16737688GFAPGFAP2.5(A_amp_#x2013;C) A_amp_#x2013 C or immunostained for TH (D_amp_#x2013;F), D_amp_#x2013 F GFAP (G_amp_#x2013;I) G_amp_#x2013 I and PT66 (J_amp_#x2013;L) J_amp_#x2013 L 
16737688GFAPGFAP2.5(A, A B or immunostained for SOD1 (C, C D GFAP (E, E F and PT66 (G, G H 
16737688GFAPGFAP2.5astrogliosis and microgliosis appear in this region as visualized by GFAP and PT66 immunostaining 
16737688GFAPGFAP2.5Immunostainings with the antibodies GFAP and PT66 revealed an increase in glial cell number and 
16737688GFAPGFAP2.5Surprisingly no differences in PT66 and GFAP staining patterns between transgenics and littermates were found in the 
16793728GFAPGFAP2.5The differentiated cells reacted positively to tubuline III GFAP and nestin 
16909005GFAPGFAP2.5Celastrol treatment reduced TNF-alpha iNOS CD40 and GFAP immunoreactivity in the lumbar spinal cord sections of celastrol-treated G93A 
16909005GFAPGFAP2.5TNF-alpha immunoreactivity co-localized with SMI-32 (neuronal neuronal marker and GFAP (astrocyte astrocyte marker 
17015226GFAPGFAP2.8their intermediate filaments (assembled assembled from glial fibrillary acidic protein GFAP and an increase in the number and size of processes 
17306794GFAPGFAP2.5a large number of cells expressing CATX and the astrocyte-marker GFAP ( Figs 4 B_amp_#x2013 B_amp_#x2033 or the microglial marker CD11b 
17306794GFAPGFAP2.5The number of CATX(+) CATX cells expressing GFAP or CD11b was substantially increased in aged mice 
17306794GFAPGFAP2.5with the neuron-marker NeuN (A, A A_amp_#x2032 A_amp_#x2033 the astrocyte-marker GFAP (B, B B_amp_#x2032 B_amp_#x2033 and the microglia-marker CD11b (C, C 
18312546GFAPGFAP-immunoreactive0.3was recovered with pioglitazone treatment and that optical densities of GFAP-immunoreactive astrocytes and Iba1-immunoreactive microglia were significantly higher in the non-treated 
18436268GFAPGFAP2.5used the primary antibody of glial fibrillary acidic protein (GFAP, GFAP 1 2000 Sigma St Louis MO USA and CD11b (1:100, 
18436268GFAPGFAP2.5In our study we used GFAP and CD11b to examine the status of microglia and astrocyte 
18436268GFAPGFAP2.5CD11b and GFAP were used as the markers of microglia (red) red and 
18464922GFAPGFAP0.3assessed by immunohistochemical staining for CD40 (microglia microglia marker and GFAP (astrocyte astrocyte marker respectively 
18464925GFAPGFAP2.5characterized by increased expression of glial fibrillary acidic protein (GFAP), GFAP a constituent of the intermediate filaments are typical of most 
18464925GFAPGFAP2.5At noncytotoxic concentrations OTA down-regulated GFAP expression while it upregulated vimentin 
12843244glial fibrillary acidic proteinglial fibrillary acidic protein1.0immunostaining of anti maci macrophage antigen i caltag burlingame ca anti gfap glial fibrillary acidic protein or anti neun neuronal specific nuclear protein chemicon temecula ca antibody and terminal deoxynucleotidyl transferase mediated biotinylated utp nick end labeling tunel assay were done using methods  
14511332glial fibrillary acidic proteinglial fibrillary acidic protein1.0to further differentiate the cellular distributions of cox 1 and cox 2 proteins a double staining procedure using a mouse monoclonal antihuman antibody to glial fibrillary acidic protein to label astrocytes gfap; dako glostrup denmark and a mouse monoclonal antihuman antibody to macrophage antigen complex 1 labelling microglia mac 1 serotec raleigh nc was used.  
14511332glial fibrillary acidic proteinglial fibrillary acidic protein1.0als amyotrophic lateral sclerosis; cox cyclooxygenase; csf cerebrospinal fluid; gfap glial fibrillary acidic protein; ir immunoreactivity; pg prostaglandins; sod superoxide dismutase.  
15572176glial fibrillary acidic proteinglial fibrillary acidic protein1.0 by proliferating and adopting a reactive phenotype characterized morphologically by hypertrophic nuclei and cell bodies and elaboration of distinct long and thick processes with increased content of glial fibrillary acidic protein gfap .  
15649489glial fibrillary acidic proteinglial fibrillary acidic protein1.0pioglitazone treatment reduced activation of microglia reduced induction of inos positive cells and less glial fibrillary acidic protein positive cells in both striatum and substantia nigra pars compacta of mptp treated mice dehmer et al. 2004 .  
15649489glial fibrillary acidic proteinglial fibrillary acidic protein1.0it reduced induction of inos positive cells and there was less glial fibrillary acidic protein positive cells in both the striatum and substantia nigra pars compacta.  
15657392glial fibrillary acidic proteinglial fibrillary acidic protein1.0abbreviations used in this paper: achr acetylcholine receptor; als amyotrophic lateral sclerosis; cna calcineurin; gfap glial fibrillary acidic protein; igf insulin like growth factor; migf 1 local isoform of igf 1; myhc myosin heavy chain; sod1 superoxide dismutase1; wt wild type.  
15657392glial fibrillary acidic proteinglial fibrillary acidic protein1.0comparable patterns of glial fibrillary acidic protein gfap immunoreactivity were found in spinal cords of sod1 n = 6 and sod /migf 1 n = 6 transgenic mice before the symptom onset 28 d; fig 5 b a b and d insert lanes 1 and 2 .  
16014720glial fibrillary acidic proteinglial fibrillary acidic protein1.0mouse mpo glial fibrillary acidic protein beta 2 integrin mac 1 cd116/cd18 neutrophil and tyrosine hydroxylase immunohistochemistry .  
16014720glial fibrillary acidic proteinglial fibrillary acidic protein1.0the primary antibodies used were rabbit polyclonal anti mpo 1:500; lab vision fremont ca rabbit polyclonal anti glial fibrillary acidic protein gfap; 1:500; chemicon temecula ca mouse monoclonal anti mac 1 1:1000; serotec raleigh nc and the monoclonal rat anti mouse neutrophil antibody mca771ga 1:100; serotec .  
16179515glial fibrillary acidic proteinglial fibrillary acidic protein1.0however it did upregulate 3 genes unaffected by the presence of the g93a/sod1 mutation: glial fibrillary acidic protein gfap stroma derived factor 1 sdf 1 and excitatory amino acid transporter 2 eaat2 .  
16436205glial fibrillary acidic proteinglial fibrillary acidic protein1.0primary astrocyte cultures from g93a sod1 or nontransgenic mice were almost exclusively astrocytic based on immunocytochemical staining with anti glial fibrillary acidic protein gfap not illustrated .  
16737688glial fibrillary acidic proteinglial fibrillary acidic protein1.0therefore we focused on the major participants in the immune response microglia/macrophages phosphotyrosine a specific and excellent marker for microglia; tillotson and wood 1989 astrocytes glial fibrillary acidic protein t cells t cell receptor cd3 and dendritic cells cd11c .  
16877542glial fibrillary acidic proteinglial fibrillary acidic protein1.0primer sequences for gp91 phox glial fibrillary acidic protein macrophage antigen complex 1 and gapdh and pcr conditions are presented in supporting text .  
17008387glial fibrillary acidic proteinglial fibrillary acidic protein1.0a constitutive proteasome 20s x was expressed in astrocytes stained with glial fibrillary acidic protein neurons stained with neun and microglia stained with cd68 .  
17008387glial fibrillary acidic proteinglial fibrillary acidic protein1.0immunohistochemistry with rabbit polyclonal anti proteasome 20s lmp7 dilution 1:500; abcam or rabbit polyclonal anti proteasome 20s x antibodies dilution 1:500; abcam and with cell markers monoclonal glial fibrillary acidic protein dilution 1:500; chemicon temecula ca monoclonal neun dilution 1:500; chemicon or monoclonal cd68 dilution 1:500; serotec oxford uk antibodies.  
17015226glial fibrillary acidic proteinglial fibrillary acidic protein1.0this includes an increase in assembly of their intermediate filaments assembled from glial fibrillary acidic protein gfap and an increase in the number and size of processes extended from the cell body figure_amp_#xa0;3 .  
17191135glial fibrillary acidic proteinglial fibrillary acidic protein1.0ho 1 increase was not only in association with neurofibrillary tangles but also co localized with senile plaques and glial fibrillary acidic protein positive astrocytes in ad brains [ 94 ].  
17306794glial fibrillary acidic proteinglial fibrillary acidic protein1.0form proform and mature form of catx the microglia/macrophage marker rat anti mouse cd11b anti cd11b; 1:50; alpha chain of a leukocyte associated protein; serotec the astrocyte marker rabbit anti cow glial fibrillary acidic protein anti gfap; 1:2500; acris and the neuronal marker mouse anti mouse neun 1:700; chemicon hampshire uk .  
18436268glial fibrillary acidic proteinglial fibrillary acidic protein1.0we used the primary antibody of glial fibrillary acidic protein gfap 1:2000 sigma st louis mo usa and cd11b 1:100 serotec oxford uk to examine the activation of astrocyte and microglia respectively.  
18464925glial fibrillary acidic proteinglial fibrillary acidic protein1.0reactive astrocytes which are characterized by increased expression of glial fibrillary acidic protein gfap a constituent of the intermediate filaments are typical of most brain pathologies.