Current Target Information
| HUGO ID | 7873 |
|---|---|
| Symbol | NOS2A |
| Name | nitric oxide synthase 2A (inducible, hepatocytes) |
| #Occurrence | 68 |
| #Paper | 20 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 17191135 | Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes. | 60 | | Neurochem Res |
| 15896810 | Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia. | 55 | | J Neurol Sci |
| 17496232 | Mitochondrial nitric oxide in the signaling of cell integrated responses. | 43 | | Am J Physiol Cell Physiol |
| 17174478 | Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair. | 42 | | Neuroscience |
| 14739060 | Neurodegenerative diseases and oxidative stress. | 33 | | Biomed Pharmacother |
| 12663085 | Glycation--a sweet tempter for neuronal death. | 26 | | Brain Res Brain Res Rev |
| 15031734 | Neurodegenerative diseases and oxidative stress. | 23 | | Nat Rev Drug Discov |
| 17634371 | Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. | 22 | | J Neurosci |
| 12909279 | Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals. | 17 | | Brain Res Bull |
| 16194581 | The beneficial effects of fruit polyphenols on brain aging. | 14 | | Neurobiol Aging |
| 11978481 | Oxidatively modified proteins in aging and disease. | 11 | | Free Radic Biol Med |
| 15964487 | Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. | 10 | | Neuroscience |
| 16242643 | Minocycline fails to protect cerebellar granular cell cultures against malonate-induced cell death. | 10 | | Neurobiol Dis |
| 17099894 | Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. | 10 | | J Comp Neurol |
| 16043017 | Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. | 10 | | Free Radic Biol Med |
| 10930589 | Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1. | 5 | | J Neurol Sci |
| 15208263 | Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells. | 5 | | FASEB J |
| 17368952 | Mutation of superoxide dismutase elevates reactive species: comparison of nitration and oxidation of proteins in different brain regions of transgenic mice with amyotrophic lateral sclerosis. | 5 | | Neuroscience |
| 9675268 | Effects of mitochondrial respiratory stimulation on membrane lipids and proteins: an electron paramagnetic resonance investigation. | 4 | | Biochim Biophys Acta |
| 11223912 | N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx. | 3 | | J Neurosci Res |