Current Target Information
| HUGO ID | 19986 |
|---|---|
| Symbol | CYCS |
| Name | cytochrome c, somatic |
| #Occurrence | 131 |
| #Paper | 20 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 15896810 | Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia. | 55 | | J Neurol Sci |
| 11679167 | Oxidative stress and signal transduction in Saccharomyces cerevisiae: insights into ageing, apoptosis and diseases. | 44 | | Mol Aspects Med |
| 17496232 | Mitochondrial nitric oxide in the signaling of cell integrated responses. | 43 | | Am J Physiol Cell Physiol |
| 14739060 | Neurodegenerative diseases and oxidative stress. | 33 | | Biomed Pharmacother |
| 11050436 | Mitochondria, oxygen free radicals, disease and ageing. | 24 | | Trends Biochem Sci |
| 17105868 | Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis. | 22 | | Mol Pharmacol |
| 17634371 | Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. | 22 | | J Neurosci |
| 16046141 | Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis. | 16 | | Neurobiol Dis |
| 10671549 | Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells. | 14 | | J Biol Chem |
| 17150307 | Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo. | 12 | | Neuroscience |
| 16050975 | Mitochondrial dysfunction and its role in motor neuron degeneration in ALS. | 11 | | Mitochondrion |
| 18210200 | Novel nanomaterials for clinical neuroscience. | 11 | | J Neuroimmune Pharmacol |
| 15964487 | Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. | 10 | | Neuroscience |
| 16242643 | Minocycline fails to protect cerebellar granular cell cultures against malonate-induced cell death. | 10 | | Neurobiol Dis |
| 16026864 | Ca2+, mitochondria and selective motoneuron vulnerability: implications for ALS. | 7 | | Trends Neurosci |
| 14698606 | Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis. Irvine, Irvine, CA 92697-4292, USA. | 5 | | Trends Neurosci |
| 11905995 | Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival. | 4 | | J Neurochem |
| 10593879 | The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids. | 3 | | FASEB J |
| 12368231 | Overexpression of SOD1 protects vulnerable motor neurons after spinal cord injury by attenuating mitochondrial cytochrome c release. | 3 | | FASEB J |
| 8899665 | Evidence against increased oxidative stress in fibroblasts from patients with non-superoxide-dismutase-1 mutant familial amyotrophic lateral sclerosis. | 2 | | J Neurol Sci |