Current Target Information
| HUGO ID | 10940 |
|---|---|
| Symbol | SLC1A2 |
| Name | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| #Occurrence | 129 |
| #Paper | 9 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 15031734 | Neurodegenerative diseases and oxidative stress. | 23 | | Nat Rev Drug Discov |
| 12893007 | 4-hydroxynonenal and neurodegenerative diseases. | 13 | | Mol Aspects Med |
| 9745361 | Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? | 9 | | Trends Pharmacol Sci |
| 12614931 | Mitochondrial dysfunction and death in motor neurons exposed to the glutathione-depleting agent ethacrynic acid. | 8 | | J Neurol Sci |
| 16026864 | Ca2+, mitochondria and selective motoneuron vulnerability: implications for ALS. | 7 | | Trends Neurosci |
| 12684448 | Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons. | 5 | | J Neurosci |
| 14698606 | Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis. Irvine, Irvine, CA 92697-4292, USA. | 5 | | Trends Neurosci |
| 14690536 | Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress. | 4 | | J Neurochem |
| 17719032 | Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS. | 4 | | Exp Neurol |