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| 10643818 | NF-kB | NF-kB | 1.3 | cGMP followed by activation of cGMP-dependent kinase and phosphorylation of NF-kB proteins and possibly CREB | |  |
| 10643818 | NF-kB | NF-kB | 1.3 | nervous system expression of heme oxygenase-1 and nuclear localization of NF-kB p50 13 are intimately associated with the outlined pathway because | | |
| 10643818 | NF-kB | NF-kB | 1.3 | because heme oxygenase-1 may activate cGMP kinase 7 while the NF-kB proteins p50 and p49 are substrates for this enzyme (Weber, | | |
| 10643818 | NF-kB | NF-kB | 1.3 | RAGE may increase lipid peroxidation as well as activation of NF-kB p50 22 | | |
| 12437573 | NF-kappaB | NF-kappaB | 0.6 | paper we report a calcineurin-dependent activation of nuclear factor-kappaB (NF-kappaB) NF-kappaB induced by the expression of familial amyotrophic lateral sclerosis (fALS)-SOD1s | | |
| 12437573 | NF-kappaB | NF-kappaB | 0.6 | of the phosphorylation state of IkappaBalpha (the the inhibitor of NF-kappaB translocation into the nucleus and induction of cyclooxygenase 2 are | | |
| 12769802 | NF-kB | NF-kB | 0.3 | the role played by the nuclear transcription factor -kB (NF-kB) NF-kB in apoptosis and in the pathogenesis of neurodegenerative disorders such | | |
| 12769802 | NF-kB | NF-kB | 0.3 | The effects of ROS and antioxidants on NF-kB function and their relevance in the pathophysiology of neurodegenerative diseases | | |
| 15896810 | NFKB | NFkB | 0.3 | transcription factors including AP-1 fos jun myc erg-1 SAPK and NFkB 3 | | |
| 15896810 | NFKB | NFkB | 0.3 | with the observation of absent activation of the redox-sensitive factor NFkB suggest that a NFkB-independent pathway that may not require free | | |
| 15896810 | NFKB | NFkB-independent | 0.3 | absent activation of the redox-sensitive factor NFkB suggest that a NFkB-independent pathway that may not require free radical signaling is responsible | | |
| 15896810 | NFKB | NFkB | 0.3 | shock response can exert its protective effects through inhibition of NFkB signaling pathway 132 | | |
| 15896810 | NFKB | NFKB | 0.3 | targeting and chaperoning of proteins degraded in proteasomes which include NFKB cyclins HSFs hypoxia-inducible factor some apoptosis-related proteins tumor necrosis factor | | |
| 15896810 | NFKB | NFkB | 0.3 | cell line it has recently been shown that curcumin inhibits NFkB activation effectively preventing neuronal cell death 159 | | |
| 17191135 | NFKB | NFkB | 0.6 | Fos/Jun Fos Jun activator protein-1 (AP-1)], AP-1 nuclear factor-kB (NFkB) NFkB and the more recently identified Nrf2 proteins 24 -26 (Fig | | |
| 17191135 | NF-kB | NF-kB | 0.6 | conferring constitutive expression inducible expression elements such as AP-1 AP-2 NF-kB Oct-1 PEA-3 Myb and the antioxidant-responsive element (ARE) ARE 71 | | |
| 17191135 | NF-kB | NF-kB | 0.6 | of critical transcription factors such as the AP-1 family members NF-kB Jun Fos p53 CREB PEBP2/CBF, PEBP2 CBF Myb all involved | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | cytokines TNF-alpha IFN-gamma and LPS that activate transcription factors like NF-kappaB or AP-1 ( 59 | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | of Akt/PKB, Akt PKB which induces cytoprotective gene expression through NF-kappaB activation ( 85 | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | the other hand proapoptotic effects of NO include inhibition of NF-kappaB decreased Bcl-2 expression ( 87 -89 118 and increased p53 | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | NO production act as a negative regulatory feedback modulator of NF-kappaB activity ( 102 | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | The stimulation or inhibition of NF-kappaB may be related to proliferative or apoptotic effects | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | NF-kappaB is activated by several agents including cytokines oxidant free radicals | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | Inappropriate activation of NF-kappaB has been linked to inflammatory events associated with autoimmune arthritis | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | In contrast complete and persistent inhibition of NF-kappaB has been linked directly to apoptosis inappropriate immune cell development | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | Disruption of the NF-kappaB gene is associated with embryo lethality many antiapoptotic pathways like | | |
| 17496232 | NF-kappaB | NF-kappaB | 0.0 | have been developed in cancer treatment including inhibition of the NF-kappaB pathway ( 144 | | |
| 17584954 | NF-kappaB | NF-kappaB | 0.0 | NF-kappaB is known to play a role in muscle atrophy ( | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | activation of nf kappa b by reactive oxygen intermediates in the nervous system. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | nuclear factor kappa b nf kappa b is a transcription factor crucially involved in glial and neuronal function. | | |
| 11228742 | nuclear factor kappa-b | nuclear factor kappa b | 1.0 | nuclear factor kappa b nf kappa b is a transcription factor crucially involved in glial and neuronal function. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | nf kappa b is ubiquitously distributed within the nervous system and its inducible activity can be discerned from constitutive activity. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | prototypic inducible nf kappa b in the nervous system is composed of the dna binding subunits p50 and p65 complexed with an inhibitory i kappa b alpha molecule. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | a number of signals from the cell surface can lead to rapid activation of nk kappa b thus releasing the inhibition by i kappa b. this activates translocation of nf kappa b to the nucleus where it binds to kappa b motifs of target genes and activates transcription. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | previous findings have identified reactive oxygen intermediates roi as a common denominator of nf kappa b activating signals. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | more specifically hydrogen peroxide h2o2 might be used as second messenger in the nf kappa b system despite its cytotoxicity. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | analysis of pathways leading to nf kappa b activation in the nervous system has identified a number of roi dependent pathways such as cytokine and neurotrophin mediated activation glutamatergic signal transduction and various diseases with cr | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | a number of nf kappa b specific target genes contribute to the production of roi or are involved in detoxification of rois. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | in this review possible mechanisms and regulatory pathways of roi mediated nf kappa b activation are discussed. | | |
| 11228742 | nf kappa b | nf kappa b | 1.0 | nf kappa b|oxidants|reactive oxygen species| | | |
| 12392777 | nuclear factor kappa-b | nuclear factor kappa b | 1.0 | another index of oxidative stress is the activation of the transcriptional factor nuclear factor kappa b nf _amp_#x3ba;b . | | |
| 16194581 | nuclear factor kappa-b | nuclear factor kappa b | 1.0 | ced signal transduction leading to the activation genes such as the inducible nitric oxide synthase inos interleukin 1_amp_#x3b2; il 1_amp_#x3b2; tumor necrosis factor _amp_#x3b1; tnf _amp_#x3b1; and nuclear factor kappa b nf _amp_#x3ba;b [1] [49] [60] [65] [69] [72] [81] and [86] . | | |