HUGO ID Detailed Result 4571

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
11173059	glutamate receptor	glutamate receptor	1.0	the presence of the glur2 subunit makes the ampa receptor impermeable to ca 2+ preventing a cascade of potentially toxic events triggered by the intracellular influx of ca 2+ ions through glutamate receptor ion channels day et al. 1995 .
11173059	glutamate receptor	glutamate receptor	1.0	in the next few years research will probably discover new and more efficacious glutamate receptor antagonists or release inhibitors and we might witness the deployment of gene therapy approaches to reduce motor neuron vulnerability to glutamatergic excitoxicity in amyotrophic lateral sclerosis pa
11173059	glutamate receptor	glutamate receptor	1.0	the glur2 subunit of the ampa glutamate receptor and/or the calcium binding proteins calbindin d28k and parvalbumin seem to be reasonable targets: increasing the expression of such genes may improve the survival of residual motor neurons in amyotro
11173059	glutamate receptor	glutamate receptor	1.0	this potential mechanism of damage to nigral neurons has already prompted a trial with remacemide a glutamate receptor antagonist in parkinson's disease parkinson study group 2000 .
12417341	glutamate receptor	glutamate receptor	1.0	these include oxidative toxicity glutamate receptor abnormality ubiquitin_amp_#x2013;proteasome dysfunction inflammatory and cytokine activation dysfunction in neurotrophic factors damage to mitochondria cytoskeletal abnormalities and activation of th
14556941	glutamate receptor	glutamate receptor	1.0	recent studies suggest that glutamate neurotoxicity is involved in the pathogenesis of multiple sclerosis ms and that treatment with glutamate receptor ampa/kainate antagonists inhibits experimental autoimmune encephalomyelitis eae the conventional model of ms. therefore we examined whether riluzole an inhibitor of glutamate transmission affects the
14556941	glutamate receptor	glutamate receptor	1.0	glutamate receptor mediated toxicity has been observed in an oligodendroglial cell line [ 28 ] and in cultures of differentiated oligodendrocytes [ 26 and 42 ] and in an animal model for ms [ 44 ].
14556941	glutamate receptor	glutamate receptor	1.0	however based on several previous studies showing that the csf glutamate levels are increased in ms patients [ 2 ] and that glutamate receptor antagonists ameliorate neurological symptoms in several forms of eae [ 38 and 43 ] it is tempting to suggest that it works by the suppression of glutamatergic neurotransmission in the cns achieved by
14739060	glutamate receptor	glutamate receptor	1.0	finally excessive response to glutamate receptor mediated stimulation occur intra cellularly [ 32 ].
16647138	glutamate receptor	glutamate receptor	1.0	brief exposures 5 min of rat brain slices to _amp_#x3b1; amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid ampa a glutamate receptor agonist elicited increases in arteriolar diameter and decreased vasomotion frequency which were not inhibited by the epoxygenase inhibitor miconazole lovick et al. 2005 .
16647138	glutamate receptor	glutamate receptor	1.0	an inhibitory action on cox 1 could possibly contribute to a reduction in glutamatergic transmission along pain recognition pathways thus enhancing analgesic activity because kynurenic acid acts as a glutamate receptor antagonist with some selectivity for the nmda receptor.
16647138	glutamate receptor	glutamate receptor	1.0	2003 in a recent multidisciplinary study gave evidence for a role of 12 lox metabolites in metabotropic glutamate receptor dependent long term depression at hippocampal ca3_amp_#x2013;ca1 synapses.
16647138	glutamate receptor	glutamate receptor	1.0	their results strongly support the hypothesis that a 12 lox pathway is required for the induction of metabotropic glutamate receptor dependent ltd but is not required for ltp.
16647138	glutamate receptor	glutamate receptor	1.0	the 12 lox metabolite of arachidonic acid 12 s hpete appeared to satisfy all the requirements of a messenger molecule that is actively recruited for the induction of metabotropic glutamate receptor dependent ltd.
16647138	glutamate receptor	glutamate receptor	1.0	this increase in cox 2 and 5 lox can be prevented by not only glutamate receptor antagonists koistinaho et al. 1999 and pepicelli et al. 2002 but also by cox 2 and 5 lox inhibitors manev et al. 2000a and pepicelli et al. 2002 indicating that generation of prostaglandins thromboxa
16647138	glutamate receptor	glutamate receptor	1.0	it is becoming increasingly evident that eicosanoid cannabinoid platelet activating factor and glutamate receptor mediated signaling mechanisms are linked through many common second messengers.
17597167	glutamate receptor	glutamate receptor	1.0	excessive glutamate receptor stimulation results in increased intracellular ca 2+ levels which gives rise to neuronal cell death excitotoxicity.
17597167	glutamate receptor	glutamate receptor	1.0	temic administration of ka is mediated not only by the ka receptor subtype of glutamate receptors but also indirectly by the release of the endogenous transmitter see [39] that can bind to all of the glutamate receptor subtypes including n methyl d aspartate nmda receptors.
18040778	glutamate receptor	glutamate receptor	1.0	the role of these receptors in neuronal microglial cell communication is not understood; however the production of glutamate and the glutamate receptor ligand quinolinic acid by activated microglia has been implicated in excitotoxicity of neurons in several neurodegenerative diseases matute et al. 2002 .