HUGO ID Detailed Result 10417

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
11173059	ubiquitin	ubiquitin	1.0	these inclusions appear concentric with a dense core surrounded by a filamentous halo and contain neurofilament proteins such as tubulin and ubiquitin forno 1996 .
11173059	ubiquitin	ubiquitin	1.0	recent studies though established a primary role for synuclein in the formation of lewy bodies and its aggregation in insoluble amyloid fibrils seems to precede the accumulation of ubiquitin and neurofilaments goedert et al. 1998 .
11173059	ubiquitin	ubiquitin	1.0	in a small german pedigree a point mutation in exon 4 of the ubiquitin carboxy terminal hydrolase l1 uch l1 gene has been detected on chromosome 4 indicating that abnormal proteolytic mechanisms may favor aggregation and ubiquitination of proteins like synuclein leroy e
11173059	ubiquitin	ubiquitin	1.0	they are composed of hyperphosphorylated insoluble forms of microtubule associated protein tau often conjugated with ubiquitin selkoe 1999 .
12417341	ubiquitin	ubiquitin	1.0	real time rt pcr verified that the expression level of the following six genes was altered in sals: dorfin metallothionein 3 30 kda tata binding protein associated factor neugrin ubiquitin like protein 5 and macrophage inhibiting factor related protein 8.
12417341	ubiquitin	ubiquitin	1.0	vealed that clones 2 7 8 and 11 were identical to four known cdnas 30 kda tata binding protein associated factor tafii30 macrophage inhibiting factor related protein 8 mrp8 metallothionein 3 mt 3 and ubiquitin like protein 5 ubl5 respectively.
12417341	ubiquitin	ubiquitin	1.0	ubl5 is one of the ubiquitin like proteins.
12417341	ubiquitin	ubiquitin	1.0	it may possibly organize another ubiquitin like system but its function remains unknown [ 26 ].
14511332	ubiquitin	ubiquitin	1.0	this is consistent with other studies showing an altered protein expression e.g. ubiquitin stephens et al . 2001 and an active involvement of interneurons in the pathology of als rowland _amp_ shneider 2001 .
14739060	ubiquitin	ubiquitin	1.0	g93a transgenic mouse [ 46 50 47 48 and 49 ]. _amp_#x2022; protein misfolding and aggregates: for example of a_amp_#x3b2; 42 for ad [ 43 ]. _amp_#x2022; proteasome dysfunction on ubiquinited material ubiquitin forms covalent bonds with other protein in order to mark them for degradation by an atp dependent non lysosomial proteolytic system i.e proteasome . _amp_#x2022; oxidative stress mitochondria dysfunc
14739060	ubiquitin	ubiquitin	1.0	tion of proteins: microtubular tau protein for the former accumulation of several aggregated proteins _amp_#x3b2; amyloid especially its toxic form a_amp_#x3b2; 42 apoe [ 43 ] hyperphosphorylated tau ubiquitin presenilin 1_amp_#xa0;and 2 with an inflammatory reaction around the deposit of _amp_#x3b2; amyloid for the latter [ 38 ].
14739060	ubiquitin	ubiquitin	1.0	as demonstrated in transgenic mouse this abnormal protein is cleaved to fragments conjugated with ubiquitin; which aggregate forming neuronal intra nuclear inclusions.
17008387	ubiquitin	ubiquitin	1.0	polyclonal anti proteasome 20s x dilution 1:1000; abcam rabbit polyclonal anti glt 1 dilution 1:1000; calbiochem la jolla ca monoclonal anti beta actin dilution 1:4000 sigma or rabbit polyclonal anti ubiquitin antibodies dilution 1:1000; dakocytomation denmark a/s glostrup denmark and horseradish peroxidase labeled anti mouse igg dilution 1:4000; ge healthcare or horseradish peroxidase labeled anti rabbit
17015226	ubiquitin	ubiquitin	1.0	it has also been used to define accumulations of detergent insoluble forms of proteins including sod1 that are detected by immunoblotting of filter trappable material as well as small sod1 or ubiquitin positive fibrillar inclusions in spinal cord sections deng et_amp_#xa0;al. 2006 furukawa et_amp_#xa0;al. 2006 johnston et_amp_#xa0;al. 2000 jonsson et_amp_#xa0;al. 2004 jonsson et_amp_#xa0;al. 2006 w
17015226	ubiquitin	ubiquitin	1.0	aggregates found in als patients as well as mouse models contain ubiquitin ince et_amp_#xa0;al. 1998 wang et_amp_#xa0;al. 2003 and watanabe et_amp_#xa0;al. 2001 a protein adduct which typically targets proteins for disposal via the proteasome.
17191135	ubiquitin	ubiquitin	1.0	some of the known hsps include ubiquitin hsp10 hsp27 hsp32 or ho 1 hsp47 hsp60 hsc70 hsp70 or hsp72 hsp90 and hsp100/105.
17191135	ubiquitin	ubiquitin	1.0	chip_amp_#8217;s is a ubiquitin e3 ligase that can collaborate with molecular chaperones to facilitate protein folding and prevent protein aggregation.
17306794	ubiquitin	ubiquitin	1.0	all cells are dependent on the two major proteolytic systems within cells the ubiquitin proteasome and the lysosomal system to control the stability function and intracellular localization of a wide variety of proteins rivett 1990 and bohley 1995 .
17569578	ubiquitin	ubiquitin	1.0	a series of independent studies found that ppar_amp_#x3b3; activation regulated both cellular app levels and a_amp_#x3b2; production by stimulating the ubiquitin mediated degradation of app [45] .
18397603	ubiquitin	ubiquitin	1.0	local expression of migf 1 modulates ubiquitin caspase and cdk5 expression in skeletal muscle of an als mouse model.
18397603	ubiquitin	ubiquitin	1.0	results and discussion: ubiquitin expression and caspase activity resulted markedly increased in sod g93a muscle but maintained at very low levels in the sod g93a x mlc/migf 1 sod g93a /migf 1 transgenic muscle.
18464922	ubiquitin	ubiquitin	1.0	recently an alternative mechanism suggested that a functionally distinct pool of ppar _amp_#x003b3; is susceptible to ligand dependent sumoylation covalent attachment of small ubiquitin like modifier at lysine 365 leading to recruitment and stabilization of nuclear corepressor n cor complexes at the promoters of proinflammatory genes thereby repressing them [ 32 ].