Current Target Information
| HUGO ID | 1504 |
|---|---|
| Symbol | CASP3 |
| Name | caspase 3, apoptosis-related cysteine peptidase |
| #Occurrence | 72 |
| #Paper | 11 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 15896810 | Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia. | 55 | | J Neurol Sci |
| 17496232 | Mitochondrial nitric oxide in the signaling of cell integrated responses. | 43 | | Am J Physiol Cell Physiol |
| 17105868 | Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis. | 22 | | Mol Pharmacol |
| 10742195 | Metals and neuroscience. | 20 | | Curr Opin Chem Biol |
| 16046141 | Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis. | 16 | | Neurobiol Dis |
| 10671549 | Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells. | 14 | | J Biol Chem |
| 17150307 | Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo. | 12 | | Neuroscience |
| 16242643 | Minocycline fails to protect cerebellar granular cell cultures against malonate-induced cell death. | 10 | | Neurobiol Dis |
| 16406002 | Neuroprotective role for carbonyl reductase? | 7 | | Biochem Biophys Res Commun |
| 12901835 | Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine. | 6 | | Neurobiol Dis |
| 15208263 | Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells. | 5 | | FASEB J |