HUGO ID Detailed Result 11920

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
10643818	FAS	Fas	0.6	TNF-receptor-dependent signaling 9 10 and 11 and engagement of the Fas antigen 12
15964487	FAS	Fas-ligand	0.3	pathways initiated by several apoptotic stimuli including receptor activation by Fas-ligand ( Kavurma and Khachigian 2003 or glutamate ( Stout et
16242643	FAS	Fas	0.3	hydroperoxide phenylarsine oxide or non-oxidative (Ca/Pi, Ca Pi t-Bid Bid Fas mechanism ( Chu et al. 2005 Wang et al. 2003
16406002	FAS	FAS-independent	0.3	the activation of caspases and to DNA fragmentation through a FAS-independent and mitochondria-linked pro-apoptotic signal pathway
17105868	FAS	Fas	2.9	The Fas pathway and oxidative stress mediate neuronal death in stroke and
17105868	FAS	Fas	2.9	The proapoptotic proteins Fas Fas-associated death domain caspase 8 and caspase 3 were also
17105868	FAS	Fas-associated	2.1	The proapoptotic proteins Fas Fas-associated death domain caspase 8 and caspase 3 were also elevated
17105868	FAS	Fas	2.9	In experiments investigating oxidative stress and activation of the Fas pathway mice received Neu2000 (30 30 mg/kg/day), mg kg day
17105868	FAS	Fas	2.9	The following primary antibodies were used Fas FADD (BD BD Bioscience Franklin Lakes NJ cleaved caspase 3
17105868	FAS	Fas	2.9	We found that expression of Fas and FADD were increased selectively in the ventral motor neurons
17105868	FAS	Fas-signaling	1.8	In motor neurons of ALS mice the Fas-signaling pathway remained activated after complete blockade of oxidative stress by
17105868	FAS	Fas	2.9	In support of this Li blocked activation of the Fas pathway during serum deprivation-induced apoptosis and attenuated motor neuron degeneration
17105868	FAS	Fas	2.9	and attenuated motor neuron degeneration as well as activation of Fas caspase 8 and caspase 3 in the spinal cords of
17105868	FAS	Fas	2.9	conclusion the present study suggests that oxidative stress and the Fas death pathway constitute two separate routes of the motor neuron
17105868	FAS	Fas	2.9	The Fas pathway is slowly activated even in the blockade of oxidative
17105868	FAS	Fas	2.9	Thus targeting both oxidative stress and the Fas apoptosis pathway with concurrent treatment with Neu2000 and Li may
17105868	FAS	Fas	2.9	A Western blot analysis showing expression of Fas FADD and actin in lumbar segments from control or G93A
17105868	FAS	Fas	2.9	Levels of Fas (b) b and FADD (c) c were measured and scaled
17105868	FAS	Fas	2.9	Western blot analysis of FADD and Fas after immunoprecipitation with Fas antibody in the same samples shown
17105868	FAS	Fas	2.9	Western blot analysis of FADD and Fas after immunoprecipitation with Fas antibody in the same samples shown above (d) d
17105868	FAS	Fas	2.9	(b) b at 12 weeks of age after immuno-labeling with Fas antibody
17105868	FAS	Fas	2.9	Note increased levels of Fas in the motor neurons (arrows) arrows from G93A mice
17105868	FAS	Fas	2.9	Western blot analysis of FADD after immunoprecipitation (IP) IP with Fas antibody cleaved caspase 8 cleaved caspase 3 and actin in
17105868	FAS	Fas	2.9	F Western blot analysis of Fas FADD cleaved caspase 8 cleaved caspase 3 and actin in
17105868	FAS	Fas	2.9	Fas- and Fas ligand-mediated apoptosis plays a role in neuronal loss in animal
17105868	FAS	Fas	2.9	We examined whether the Fas pathway would mediate apoptosis in ALS mice
17105868	FAS	Fas	2.9	Expression of Fas and its cytoplasmic adaptor protein FADD and Fas-FADD interaction were
17105868	FAS	Fas	2.9	Immunohistochemistry revealed that Fas expression was increased selectively in large spinal motor neurons of
17105868	FAS	Fas	2.9	These findings suggest that Fas FADD caspase 8 and caspase 3 are activated in spinal
17105868	FAS	Fas-signaling	1.8	No activation of the Fas-signaling molecules in G93A mice was detectable at 16 weeks of
17105868	FAS	Fas	2.9	We also investigated whether serum deprivation would activate the Fas apoptosis pathway and whether this activation was sensitive to Li
17105868	FAS	Fas	2.9	Interaction of FADD with Fas cleaved caspase 8 and cleaved caspase 3 were all increased
17105868	FAS	Fas	2.9	the diet slightly but statistically insignificantly attenuated the increase in Fas FADD and cleaved caspase 8 and caspase 3 in the
17105868	FAS	Fas	2.9	noteworthy that daily administration of Li completely blocked activation of Fas and its downstream mediators in G93A mice
17105868	FAS	Fas	2.9	Neu2000 can block both oxidative stress and activation of the Fas apoptosis pathway induced in the spinal cords of G93A mice
17105868	FAS	Fas-associated	2.1	S R -sulfoximine SOD superoxide dismutase LDH lactate dehydrogenase FADD Fas-associated death domain
17496232	FAS	Fas	0.6	the extrinsic pathway binding of membrane ligands like TNF-alpha and Fas to membrane receptors triggers the activation of caspases and the
17634371	FAS	Fas	0.3	was obtained from Harlan (Madison, Madison WI recombinant human soluble Fas ligand and tert -butylhydroquinone (tBHQ) tBHQ from Alexis (San San
17634371	FAS	Fas	0.3	Soluble Fas ligand was added in the presence of enhancer antibody (1
17634371	FAS	Fas	0.3	observed for other apoptotic stimuli including trophic factor deprivation and Fas (Est_amp_eacute;vez Est_amp_eacute vez et al 1998 Raoul et al. 2002
17634371	FAS	Fas	0.3	G37R G85R or G93A display increased susceptibility to activation of Fas apoptotic pathway but not to trophic factor deprivation or excitotoxic
17634371	FAS	Fas	0.3	Nevertheless for other apoptotic stimuli including Fas (Raoul Raoul et al. 2002 and trophic factor deprivation (Est_amp_eacute;vez
17634371	FAS	Fas-apoptotic	0.3	death occurring in neuropathological conditions involving either p75 - or Fas-apoptotic signaling
17634371	FAS	Fas	0.3	we analyzed the effect of tBHQ on apoptosis induced by Fas ligand in SOD1 -expressing motor neurons
17634371	FAS	Fas	0.3	The soluble extracellular domain of Fas ligand (sFasL) sFasL in the presence of an enhancer antibody
10643818	fas antigen	fas antigen	1.0	erm potentiation has been attributed to programmed cell death in t lymphocytes [ 7 and 8 ] and has been inferred from studies of tnf receptor dependent signaling [ 9 10 and 11 ] and engagement of the fas antigen [ 12 ].
15896810	apo 1	apo 1	1.0	it also protects against fas apo 1 staurosporine tnf and etoposside induced apoptotic cell death as well as h 2 o 2 induced necrosis [147] .