SciMiner Pathway Enrichment Full Result

SciMiner Pathway Enrichment Full Result

Full Enrichment Result Pathways (sorted by p-value)

# of targets in test set	399	# of targets in background set	555	Switch table detail

Rank	PathwayID	Title	t+	t-	t+ uniq	com mon	b+ uniq	b+	b-	p-value	t-ratio	b-ratio	enrichment folds
1	73894	DNA Repair	18	381	18	0	1	1	554	1.42e-06	0.05	0.00	25.0
2	73890	Double-Strand Break Repair	8	391	8	0	0	0	555	8.98e-04	0.02	0.00	bZero
3	hsa04080	Neuroactive ligand-receptor interaction - Homo sapiens (human)	8	391	3	5	29	34	521	2.08e-03	0.02	0.06	0.3
4	hsa04060	Cytokine-cytokine receptor interaction - Homo sapiens (human)	20	379	2	18	39	57	498	3.61e-03	0.05	0.10	0.5
5	73951	Homologous recombination repair of replication-independent double-strand breaks	6	393	6	0	0	0	555	5.24e-03	0.02	0.00	bZero
6	157579	Telomere Maintenance	6	393	6	0	0	0	555	5.24e-03	0.02	0.00	bZero
7	73888	Homologous Recombination Repair	6	393	6	0	0	0	555	5.24e-03	0.02	0.00	bZero
8	hsa04514	Cell adhesion molecules (CAMs) - Homo sapiens (human)	3	396	0	3	13	16	539	1.95e-02	0.01	0.03	0.3
9	hsa00620	Pyruvate metabolism - Homo sapiens (human)	8	391	8	0	2	2	553	2.05e-02	0.02	0.00	5.6
10	hsa04610	Complement and coagulation cascades - Homo sapiens (human)	1	398	0	1	9	10	545	3.05e-02	0.00	0.02	0.1
11	hsa00480	Glutathione metabolism - Homo sapiens (human)	9	390	6	3	1	4	551	0.05	0.02	0.01	3.1
12	hsa05214	Glioma - Homo sapiens (human)	19	380	11	8	6	14	541	0.07	0.05	0.03	1.9
13	76010	Homologous DNA pairing and strand exchange	3	396	3	0	0	0	555	0.07	0.01	0.00	bZero
14	69190	DNA strand elongation	3	396	3	0	0	0	555	0.07	0.01	0.00	bZero
15	hsa02010	ABC transporters - General - Homo sapiens (human)	3	396	3	0	0	0	555	0.07	0.01	0.00	bZero
16	75154	Recruitment of repair and signaling proteins to double-strand breaks	3	396	3	0	0	0	555	0.07	0.01	0.00	bZero
17	69481	G2/M Checkpoints	3	396	3	0	0	0	555	0.07	0.01	0.00	bZero
18	76003	Presynaptic phase of homologous DNA pairing and strand exchange	3	396	3	0	0	0	555	0.07	0.01	0.00	bZero
19	69242	S Phase	6	393	5	1	1	2	553	0.07	0.02	0.00	4.2
20	hsa03320	PPAR signaling pathway - Homo sapiens (human)	2	397	1	1	9	10	545	0.09	0.01	0.02	0.3
21	hsa04115	p53 signaling pathway - Homo sapiens (human)	14	385	7	7	2	9	546	0.09	0.04	0.02	2.2
22	69239	Synthesis of DNA	5	394	4	1	0	1	554	0.09	0.01	0.00	7.0
23	hsa04630	Jak-STAT signaling pathway - Homo sapiens (human)	14	385	4	10	23	33	522	0.10	0.04	0.06	0.6
24	hsa05222	Small cell lung cancer - Homo sapiens (human)	22	377	9	13	5	18	537	0.10	0.06	0.03	1.7
25	187037	TRKA signalling from the plasma membrane	15	384	7	8	3	11	544	0.11	0.04	0.02	1.9
26	hsa04012	ErbB signaling pathway - Homo sapiens (human)	20	379	9	11	5	16	539	0.12	0.05	0.03	1.7
27	166520	Signalling by NGF	20	379	9	11	5	16	539	0.12	0.05	0.03	1.7
28	hsa00190	Oxidative phosphorylation - Homo sapiens (human)	10	389	8	2	4	6	549	0.12	0.03	0.01	2.3
29	69278	Cell Cycle, Mitotic	10	389	9	1	5	6	549	0.12	0.03	0.01	2.3
30	hsa00790	Folate biosynthesis - Homo sapiens (human)	5	394	3	2	0	2	553	0.14	0.01	0.00	3.5
31	hsa00650	Butanoate metabolism - Homo sapiens (human)	5	394	4	1	1	2	553	0.14	0.01	0.00	3.5
32	hsa00350	Tyrosine metabolism - Homo sapiens (human)	8	391	6	2	2	4	551	0.14	0.02	0.01	2.8
33	hsa00010	Glycolysis / Gluconeogenesis - Homo sapiens (human)	8	391	7	1	3	4	551	0.14	0.02	0.01	2.8
34	hsa05213	Endometrial cancer - Homo sapiens (human)	14	385	8	6	4	10	545	0.14	0.04	0.02	1.9
35	114608	Platelet degranulation	4	395	0	4	9	13	542	0.14	0.01	0.02	0.4
36	114611	Exocytosis of Alpha granule	4	395	0	4	9	13	542	0.14	0.01	0.02	0.4
37	hsa05220	Chronic myeloid leukemia - Homo sapiens (human)	17	382	8	9	5	14	541	0.14	0.04	0.03	1.7
38	140192	Metabolism of xenobiotics	11	388	7	4	4	8	547	0.16	0.03	0.01	1.9
39	69620	Cell Cycle Checkpoints	8	391	6	2	3	5	550	0.17	0.02	0.01	2.2
40	hsa04070	Phosphatidylinositol signaling system - Homo sapiens (human)	8	391	4	4	1	5	550	0.17	0.02	0.01	2.2
41	69306	DNA Replication	8	391	7	1	4	5	550	0.17	0.02	0.01	2.2
42	hsa00020	Citrate cycle (TCA cycle) - Homo sapiens (human)	4	395	3	1	0	1	554	0.17	0.01	0.00	5.6
43	69166	Removal of the Flap Intermediate	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
44	hsa04340	Hedgehog signaling pathway - Homo sapiens (human)	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
45	110373	Resolution of AP sites via the multiple-nucleotide patch replacement pathway	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
46	hsa00290	Valine, leucine and isoleucine biosynthesis - Homo sapiens (human)	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
47	hsa00430	Taurine and hypotaurine metabolism - Homo sapiens (human)	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
48	hsa04740	Olfactory transduction - Homo sapiens (human)	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
49	110362	Removal of DNA patch containing abasic residue	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
50	140179	Amine Oxidase reactions	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
51	174414	Processive synthesis on the C-strand of the telomere	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
52	141333	Monoamines are oxidized to aldehydes, producing NH3 and H2O2	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
53	83572	MRN complex relocalizes to nuclear foci	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
54	75177	Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
55	75924	Processing of DNA ends prior to end rejoining	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
56	69186	Lagging Strand Synthesis	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
57	71384	Ethanol catabolism	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
58	73889	Nonhomologous End-joining (NHEJ)	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
59	hsa00040	Pentose and glucuronate interconversions - Homo sapiens (human)	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
60	162592	Integration of provirus	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
61	180786	Extension of Telomeres	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
62	174417	Telomere C-strand (Lagging Strand) Synthesis	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
63	176187	Activation of ATR in response to replication stress	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
64	73933	Resolution of Abasic Sites (AP sites)	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
65	174437	Removal of the Flap Intermediate from the C-strand	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
66	69183	Processive synthesis on the lagging strand	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
67	76000	Assembly of the RAD51-ssDNA nucleoprotein complex	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
68	73884	Base Excision Repair	2	397	2	0	0	0	555	0.17	0.01	0.00	bZero
69	71406	Pyruvate metabolism and TCA cycle	6	393	5	1	2	3	552	0.18	0.02	0.01	2.8
70	hsa05223	Non-small cell lung cancer - Homo sapiens (human)	16	383	8	8	5	13	542	0.18	0.04	0.02	1.7
71	hsa04916	Melanogenesis - Homo sapiens (human)	12	387	6	6	3	9	546	0.18	0.03	0.02	1.9
72	198203	PI3K/AKT signalling	9	390	4	5	1	6	549	0.19	0.02	0.01	2.1
73	hsa04920	Adipocytokine signaling pathway - Homo sapiens (human)	9	390	0	9	12	21	534	0.19	0.02	0.04	0.6
74	hsa05218	Melanoma - Homo sapiens (human)	17	382	9	8	7	15	540	0.20	0.04	0.03	1.6
75	163200	Electron Transport Chain	10	389	8	2	5	7	548	0.21	0.03	0.01	2.0
76	hsa00251	Glutamate metabolism - Homo sapiens (human)	7	392	4	3	1	4	551	0.22	0.02	0.01	2.4
77	hsa04720	Long-term potentiation - Homo sapiens (human)	10	389	4	6	2	8	547	0.24	0.03	0.01	1.7
78	76005	Response to elevated platelet cytosolic Ca++	5	394	0	5	9	14	541	0.24	0.01	0.03	0.5
79	170984	ARMS-mediated activation	4	395	2	2	0	2	553	0.24	0.01	0.00	2.8
80	169893	Prolonged ERK activation events	4	395	2	2	0	2	553	0.24	0.01	0.00	2.8
81	170968	Frs2-mediated activation	4	395	2	2	0	2	553	0.24	0.01	0.00	2.8
82	71403	Citric acid cycle (TCA cycle)	4	395	3	1	1	2	553	0.24	0.01	0.00	2.8
83	187706	Signalling to p38 via RIT and RIN	4	395	2	2	0	2	553	0.24	0.01	0.00	2.8
84	71408	Metabolism of small molecules	4	395	2	2	0	2	553	0.24	0.01	0.00	2.8
85	69615	G1/S DNA Damage Checkpoints	4	395	2	2	0	2	553	0.24	0.01	0.00	2.8
86	77388	SHC-related events	4	395	2	2	0	2	553	0.24	0.01	0.00	2.8
87	190236	Signaling by FGFR	1	398	0	1	5	6	549	0.25	0.00	0.01	0.2
88	190376	FGFR ligand binding and activation	1	398	0	1	5	6	549	0.25	0.00	0.01	0.2
89	74751	Insulin receptor signalling cascade	7	392	3	4	1	5	550	0.26	0.02	0.01	1.9
90	77389	IRS-related events	7	392	3	4	1	5	550	0.26	0.02	0.01	1.9
91	109606	Intrinsic Pathway for Apoptosis	11	388	3	8	1	9	546	0.26	0.03	0.02	1.7
92	hsa05210	Colorectal cancer - Homo sapiens (human)	21	378	8	13	7	20	535	0.26	0.05	0.04	1.5
93	194138	Signaling by VEGF	3	396	0	3	7	10	545	0.26	0.01	0.02	0.4
94	hsa00340	Histidine metabolism - Homo sapiens (human)	5	394	3	2	1	3	552	0.29	0.01	0.01	2.3
95	hsa00562	Inositol phosphate metabolism - Homo sapiens (human)	5	394	2	3	0	3	552	0.29	0.01	0.01	2.3
96	162909	Host Interactions of HIV factors	5	394	2	3	0	3	552	0.29	0.01	0.01	2.3
97	hsa00260	Glycine, serine and threonine metabolism - Homo sapiens (human)	5	394	4	1	2	3	552	0.29	0.01	0.01	2.3
98	73923	Lipid and lipoprotein metabolism	7	392	4	3	13	16	539	0.29	0.02	0.03	0.6
99	74752	Signaling by Insulin receptor	9	390	4	5	2	7	548	0.31	0.02	0.01	1.8
100	15869	Nucleotide metabolism	9	390	3	6	1	7	548	0.31	0.02	0.01	1.8
101	69304	Regulation of DNA replication	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
102	69052	Switching of origins to a post-replicative state	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
103	156902	Peptide chain elongation	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
104	69580	p53-Dependent G1/S DNA damage checkpoint	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
105	72766	Translation	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
106	112410	SHC-mediated signalling	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
107	156842	Eukaryotic Translation Elongation	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
108	162594	Early Phase of HIV Life Cycle	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
109	hsa00930	Caprolactam degradation - Homo sapiens (human)	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
110	71397	Oxidative decarboxylation of pyruvate to acetyl CoA by pyruvate dehydrogenase	3	396	3	0	1	1	554	0.31	0.01	0.00	4.2
111	180292	Gab1 signalosome	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
112	69206	G1/S Transition	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
113	112412	SOS-mediated signalling	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
114	109869	MAP kinase cascade	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
115	hsa00500	Starch and sucrose metabolism - Homo sapiens (human)	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
116	69563	p53-Dependent G1 DNA Damage Response	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
117	204174	Regulation of pyruvate dehydrogenase complex (PDC)	3	396	3	0	1	1	554	0.31	0.01	0.00	4.2
118	hsa00120	Bile acid biosynthesis - Homo sapiens (human)	3	396	3	0	1	1	554	0.31	0.01	0.00	4.2
119	68949	Orc1 removal from chromatin	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
120	69300	Removal of licensing factors from origins	3	396	2	1	0	1	554	0.31	0.01	0.00	4.2
121	hsa04910	Insulin signaling pathway - Homo sapiens (human)	19	380	7	12	7	19	536	0.32	0.05	0.03	1.4
122	198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	2	397	0	2	5	7	548	0.32	0.01	0.01	0.4
123	hsa04730	Long-term depression - Homo sapiens (human)	14	385	3	11	2	13	542	0.32	0.04	0.02	1.5
124	hsa04360	Axon guidance - Homo sapiens (human)	5	394	1	4	8	12	543	0.33	0.01	0.02	0.6
125	167044	Signalling to RAS	6	393	3	3	1	4	551	0.34	0.02	0.01	2.1
126	112399	IRS-mediated signalling	6	393	3	3	1	4	551	0.34	0.02	0.01	2.1
127	hsa05020	Parkinson's disease - Homo sapiens (human)	6	393	3	3	1	4	551	0.34	0.02	0.01	2.1
128	187687	Signalling to ERKs	6	393	3	3	1	4	551	0.34	0.02	0.01	2.1
129	hsa00360	Phenylalanine metabolism - Homo sapiens (human)	6	393	4	2	2	4	551	0.34	0.02	0.01	2.1
130	hsa00380	Tryptophan metabolism - Homo sapiens (human)	6	393	4	2	2	4	551	0.34	0.02	0.01	2.1
131	hsa04912	GnRH signaling pathway - Homo sapiens (human)	15	384	7	8	6	14	541	0.34	0.04	0.03	1.5
132	hsa05030	Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human)	15	384	1	14	0	14	541	0.34	0.04	0.03	1.5
133	hsa04530	Tight junction - Homo sapiens (human)	10	389	4	6	3	9	546	0.36	0.03	0.02	1.5
134	hsa04662	B cell receptor signaling pathway - Homo sapiens (human)	10	389	2	8	1	9	546	0.36	0.03	0.02	1.5
135	hsa05211	Renal cell carcinoma - Homo sapiens (human)	11	388	4	7	15	22	533	0.37	0.03	0.04	0.7
136	hsa04210	Apoptosis - Homo sapiens (human)	32	367	7	25	11	36	519	0.37	0.08	0.06	1.2
137	hsa01510	Neurodegenerative Diseases - Homo sapiens (human)	25	374	4	21	6	27	528	0.39	0.06	0.05	1.3
138	177929	Signaling by EGFR	7	392	4	3	3	6	549	0.41	0.02	0.01	1.6
139	163685	Integration of energy metabolism	7	392	4	3	3	6	549	0.41	0.02	0.01	1.6
140	202733	Cell surface interactions at the vascular wall	7	392	4	3	3	6	549	0.41	0.02	0.01	1.6
141	168176	Toll Like Receptor 5 (TLR5) Cascade	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
142	166058	MyD88 cascade	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
143	168142	Toll Like Receptor 10 (TLR10) Cascade	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
144	168188	Toll Like Receptor TLR6:TLR2 Cascade	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
145	181438	Toll Like Receptor 2 Cascade	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
146	168179	Toll Like Receptor TLR1:TLR2 Cascade	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
147	hsa00361	gamma-Hexachlorocyclohexane degradation - Homo sapiens (human)	1	398	0	1	3	4	551	0.41	0.00	0.01	0.3
148	168181	Toll Like Receptor 7/8 (TLR7/8) Cascade	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
149	195721	Signaling by Wnt	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
150	166054	Activated TLR4 signalling	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
151	190322	FGFR4 ligand binding and activation	1	398	0	1	3	4	551	0.41	0.00	0.01	0.3
152	166016	Toll Like Receptor 4 (TLR4) Cascade	1	398	1	0	4	4	551	0.41	0.00	0.01	0.3
153	140181	Cytochrome p450	1	398	0	1	3	4	551	0.41	0.00	0.01	0.3
154	174800	Chylomicron-mediated lipid transport	1	398	0	1	4	5	550	0.41	0.00	0.01	0.3
155	190241	FGFR2 ligand binding and activation	1	398	0	1	4	5	550	0.41	0.00	0.01	0.3
156	190375	FGFR2c ligand binding and activation	1	398	0	1	4	5	550	0.41	0.00	0.01	0.3
157	190242	FGFR1 ligand binding and activation	1	398	0	1	4	5	550	0.41	0.00	0.01	0.3
158	190373	FGFR1c ligand binding and activation	1	398	0	1	4	5	550	0.41	0.00	0.01	0.3
159	174824	Lipoprotein metabolism	1	398	0	1	4	5	550	0.41	0.00	0.01	0.3
160	168138	Toll Like Receptor 9 (TLR9) Cascade	1	398	1	0	5	5	550	0.41	0.00	0.01	0.3
161	168769	BoNT Light Chain Types B, D, and F cleave VAMP/Synaptobrevin	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
162	168273	Influenza Viral RNA Transcription and Replication	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
163	73728	RNA Polymerase I Promoter Opening	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
164	70172	Phosphorylase kinase activates glycogen phosphorylase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
165	109979	Gap-filling DNA repair synthesis and ligation in TC-NER	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
166	191650	Regulation of gap junction activity	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
167	74969	Gap-filling DNA repair synthesis and ligation in GG-NER	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
168	168255	Influenza Life Cycle	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
169	174403	Glutathione synthesis	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
170	188108	MyD88 Cascade (Murine)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
171	164843	2-LTR circle formation	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
172	73621	Pyrimidine catabolism	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
173	159236	Transport of Mature mRNA derived from an Intron-Containing Transcript	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
174	180897	Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
175	68962	Activation of the pre-replicative complex	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
176	hsa00950	Alkaloid biosynthesis I - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
177	hsa03030	DNA replication - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
178	hsa00770	Pantothenate and CoA biosynthesis - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
179	171306	Packaging Of Telomere Ends	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
180	162585	Uncoating of the HIV Virion	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
181	83542	ATM mediated response to DNA double-strand break	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
182	168782	Proteolytic cleavage of SNARE complex proteins	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
183	112407	RAF phosphorylates MEK	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
184	71336	Pentose phosphate pathway (hexose monophosphate shunt)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
185	168799	Botulinum neurotoxicity	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
186	70845	Isoleucine catabolism	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
187	180689	APOBEC3G mediated resistance to HIV-1 infection	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
188	71037	Oxidative decarboxylation of alpha-ketoadipate to glutaryl CoA by alpha-ketoglutarate dehydrogenase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
189	69091	Polymerase switching	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
190	71383	Acetate, ATP, and coenzyme A react to form acetyl CoA, AMP, and pyrophosphate	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
191	110049	MEK activation	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
192	168325	Viral Messenger RNA Synthesis	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
193	73930	Base-free sugar-phosphate removal via the single-nucleotide replacement pathway	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
194	73927	Depurination	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
195	69109	Leading Strand Synthesis	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
196	68886	M Phase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
197	176033	Interactions of Vpr with host cellular proteins	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
198	71064	Lysine catabolism	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
199	71338	Ethanol is oxidized by NAD+ to form acetaldehyde, NADH, and H+	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
200	hsa00740	Riboflavin metabolism - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
201	hsa00460	Cyanoamino acid metabolism - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
202	114294	Activation, translocation and oligomerization of BAX	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
203	162589	Reverse Transcription of HIV RNA	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
204	70853	Oxidative decarboxylation of alpha-ketoisovalerate to isobutyryl-CoA by branched-chain alpha-ketoacid dehydrogenase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
205	77378	Formation of Cytosolic Glycerol-3-phosphate	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
206	110056	ERK1 activation	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
207	68875	Mitotic Prophase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
208	164525	Plus-strand DNA synthesis	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
209	163358	PKA-mediated phosphorylation of key metabolic factors	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
210	73929	Base-Excision Repair, AP Site Formation	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
211	hsa01030	Glycan structures - biosynthesis 1 - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
212	109977	Repair synthesis for gap-filling by DNA polymerase in TC-NER	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
213	192456	Digestion of dietary lipid	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
214	174411	Polymerase switching on the C-strand of the telomere	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
215	110381	Resolution of AP sites via the single-nucleotide replacement pathway	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
216	163560	Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
217	hsa00052	Galactose metabolism - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
218	210991	Basigin interactions	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
219	69473	G2/M DNA damage checkpoint	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
220	71401	Oxidative decarboxylation of alpha-ketoglutarate to succinyl CoA by alpha-ketoglutarate dehydrogenase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
221	110330	Recognition and association of DNA glycosylase with site containing an affected purine	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
222	164516	Minus-strand DNA synthesis	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
223	hsa00030	Pentose phosphate pathway - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
224	111452	Activation and oligomerization of BAK protein	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
225	142045	Alcohol Dehydrogenase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
226	hsa00510	N-Glycan biosynthesis - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
227	71182	Phenylalanine and tyrosine catabolism	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
228	142033	Ethanol Catabolism	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
229	110331	Cleavage of the damaged purine	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
230	70726	Oxidative decarboxylation of alpha-ketoisocaproate to isovaleryl-CoA by branched-chain alpha-ketoacid dehydrogenase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
231	hsa04130	SNARE interactions in vesicular transport - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
232	188081	Toll Like Receptor 11 (TLR11) Cascade (Murine)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
233	74967	Repair synthesis of patch ~27-30 bases long by DNA polymerase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
234	hsa00051	Fructose and mannose metabolism - Homo sapiens (human)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
235	176974	Unwinding of DNA	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
236	71032	Propionyl-CoA catabolism	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
237	187577	SCF(Skp2)-mediated degradation of p27/p21	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
238	110357	Displacement of DNA glycosylase by APE1	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
239	70221	Glycogen breakdown (glycogenolysis)	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
240	75148	ATM mediated phosphorylation of repair proteins	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
241	162658	Golgi Cisternae Pericentriolar Stack Reorganization	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
242	191647	c-src mediated regulation of Cx43 function and closure of gap junctions	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
243	70794	Oxidative decarboxylation of alpha-keto-beta-methylvalerate to alpha-methylbutyryl-CoA by branched-chain alpha-ketoacid dehydrogenase	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
244	75894	Synthesis of lysophosphatidic acid from glycerol-3-phosphate	1	398	1	0	0	0	555	0.42	0.00	0.00	bZero
245	hsa04370	VEGF signaling pathway - Homo sapiens (human)	20	379	6	14	7	21	534	0.42	0.05	0.04	1.3
246	hsa05221	Acute myeloid leukemia - Homo sapiens (human)	13	386	5	8	5	13	542	0.42	0.03	0.02	1.4
247	109582	Hemostasis	17	382	6	11	19	30	525	0.45	0.04	0.05	0.8
248	194840	Rho GTPase cycle	4	395	2	2	1	3	552	0.46	0.01	0.01	1.9
249	202131	Metabolism of nitric oxide	4	395	1	3	0	3	552	0.46	0.01	0.01	1.9
250	114509	Platelet activation triggers	4	395	1	3	0	3	552	0.46	0.01	0.01	1.9
251	hsa00252	Alanine and aspartate metabolism - Homo sapiens (human)	4	395	4	0	3	3	552	0.46	0.01	0.01	1.9
252	76002	Platelet Activation	4	395	1	3	0	3	552	0.46	0.01	0.01	1.9
253	71387	Metabolism of carbohydrates	4	395	2	2	1	3	552	0.46	0.01	0.01	1.9
254	198725	Nuclear Events (kinase and transcription factor activation)	4	395	1	3	0	3	552	0.46	0.01	0.01	1.9
255	164378	PKA activation in glucagon signalling	4	395	1	3	0	3	552	0.46	0.01	0.01	1.9
256	hsa00410	beta-Alanine metabolism - Homo sapiens (human)	4	395	3	1	2	3	552	0.46	0.01	0.01	1.9
257	hsa05215	Prostate cancer - Homo sapiens (human)	23	376	9	14	12	26	529	0.46	0.06	0.05	1.2
258	75153	Apoptotic execution phase	2	397	0	2	4	6	549	0.48	0.01	0.01	0.5
259	111465	Cleavage of cellular proteins by active caspases	2	397	0	2	4	6	549	0.48	0.01	0.01	0.5
260	202403	TCR signaling	9	390	2	7	2	9	546	0.48	0.02	0.02	1.4
261	162906	HIV Infection	9	390	5	4	5	9	546	0.48	0.02	0.02	1.4
262	hsa04930	Type II diabetes mellitus - Homo sapiens (human)	9	390	3	6	3	9	546	0.48	0.02	0.02	1.4
263	hsa04010	MAPK signaling pathway - Homo sapiens (human)	37	362	9	28	16	44	511	0.48	0.09	0.08	1.2
264	hsa04664	Fc epsilon RI signaling pathway - Homo sapiens (human)	17	382	5	12	6	18	537	0.49	0.04	0.03	1.3
265	hsa04810	Regulation of actin cytoskeleton - Homo sapiens (human)	13	386	5	8	16	24	531	0.50	0.03	0.04	0.8
266	hsa00561	Glycerolipid metabolism - Homo sapiens (human)	5	394	5	0	4	4	551	0.50	0.01	0.01	1.7
267	hsa04660	T cell receptor signaling pathway - Homo sapiens (human)	18	381	3	15	5	20	535	0.51	0.05	0.04	1.3
268	hsa04670	Leukocyte transendothelial migration - Homo sapiens (human)	14	385	3	11	14	25	530	0.51	0.04	0.05	0.8
269	hsa00980	Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human)	3	396	1	2	5	7	548	0.53	0.01	0.01	0.6
270	194313	VEGF ligand-receptor interactions	3	396	0	3	4	7	548	0.53	0.01	0.01	0.6
271	168180	TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade	6	393	1	5	0	5	550	0.54	0.02	0.01	1.7
272	168164	Toll Like Receptor 3 (TLR3) Cascade	6	393	1	5	0	5	550	0.54	0.02	0.01	1.7
273	hsa00230	Purine metabolism - Homo sapiens (human)	6	393	3	3	2	5	550	0.54	0.02	0.01	1.7
274	75178	Formation of Platelet plug	9	390	1	8	9	17	538	0.55	0.02	0.03	0.7
275	73847	Purine metabolism	6	393	1	5	1	6	549	0.57	0.02	0.01	1.4
276	hsa01430	Cell Communication - Homo sapiens (human)	4	395	1	3	6	9	546	0.57	0.01	0.02	0.6
277	202670	ERKs are inactivated	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
278	68867	Assembly of the pre-replicative complex	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
279	69202	Cyclin E associated events during G1/S transition	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
280	210993	Tie2 Signaling	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
281	72613	Eukaryotic Translation Initiation	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
282	69236	G1 Phase	2	397	2	0	1	1	554	0.57	0.01	0.00	2.8
283	70894	Valine catabolism	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
284	hsa00641	3-Chloroacrylic acid degradation - Homo sapiens (human)	2	397	2	0	1	1	554	0.57	0.01	0.00	2.8
285	173107	Binding and entry of HIV virion	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
286	111742	Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (glutaredoxin)	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
287	156590	Glutathione conjugation	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
288	156580	Phase II conjugation	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
289	hsa00630	Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
290	157279	3' -UTR-mediated translational regulation	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
291	hsa00720	Reductive carboxylate cycle (CO2 fixation) - Homo sapiens (human)	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
292	114604	Collagen-mediated activation cascade	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
293	69002	DNA Replication Pre-Initiation	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
294	72737	Cap-dependent Translation Initiation	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
295	68874	M/G1 Transition	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
296	69231	Cyclin D associated events in G1	2	397	2	0	1	1	554	0.57	0.01	0.00	2.8
297	72764	Eukaryotic Translation Termination	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
298	111747	Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and glutaredoxin	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
299	74749	Signal attenuation	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
300	171007	p38MAPK events	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
301	69656	Cyclin A:Cdk2-associated events at S phase entry	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
302	hsa00600	Sphingolipid metabolism - Homo sapiens (human)	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
303	112409	ERK activation	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
304	69541	Stabilization of p53	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
305	72706	GTP hydrolysis and joining of the 60S ribosomal subunit	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
306	72689	Formation of a pool of free 40S subunits	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
307	156827	L13a-mediated translational silencing of Ceruloplasmin expression	2	397	1	1	0	1	554	0.57	0.01	0.00	2.8
308	74160	Gene Expression	7	392	4	3	4	7	548	0.59	0.02	0.01	1.4
309	hsa05060	Prion disease - Homo sapiens (human)	7	392	1	6	1	7	548	0.59	0.02	0.01	1.4
310	71291	Metabolism of amino acids	7	392	4	3	4	7	548	0.59	0.02	0.01	1.4
311	hsa05216	Thyroid cancer - Homo sapiens (human)	7	392	3	4	3	7	548	0.59	0.02	0.01	1.4
312	hsa04640	Hematopoietic cell lineage - Homo sapiens (human)	12	387	2	10	11	21	534	0.59	0.03	0.04	0.8
313	202424	Downstream TCR signaling	8	391	2	6	2	8	547	0.61	0.02	0.01	1.4
314	hsa05212	Pancreatic cancer - Homo sapiens (human)	20	379	9	11	13	24	531	0.64	0.05	0.04	1.2
315	hsa00903	Limonene and pinene degradation - Homo sapiens (human)	1	398	1	0	3	3	552	0.64	0.00	0.01	0.5
316	hsa04950	Maturity onset diabetes of the young - Homo sapiens (human)	1	398	0	1	2	3	552	0.64	0.00	0.01	0.5
317	hsa04614	Renin-angiotensin system - Homo sapiens (human)	1	398	0	1	2	3	552	0.64	0.00	0.01	0.5
318	164385	G(s)-alpha mediated events in glucagon signalling	1	398	0	1	2	3	552	0.64	0.00	0.01	0.5
319	190239	FGFR3 ligand binding and activation	1	398	0	1	2	3	552	0.64	0.00	0.01	0.5
320	157858	Gap junction trafficking and regulation	1	398	1	0	3	3	552	0.64	0.00	0.01	0.5
321	190372	FGFR3c ligand binding and activation	1	398	0	1	2	3	552	0.64	0.00	0.01	0.5
322	111748	Synthesis of deoxyribonucleoside 5'-diphosphates from ribonucleoside 5'-diphosphates	3	396	1	2	0	2	553	0.65	0.01	0.00	2.1
323	73848	Pyrimidine metabolism	3	396	1	2	0	2	553	0.65	0.01	0.00	2.1
324	70326	Glucose metabolism	3	396	1	2	0	2	553	0.65	0.01	0.00	2.1
325	hsa04320	Dorso-ventral axis formation - Homo sapiens (human)	3	396	2	1	1	2	553	0.65	0.01	0.00	2.1
326	198323	AKT phosphorylates targets in the cytosol	3	396	2	1	1	2	553	0.65	0.01	0.00	2.1
327	111458	Formation of apoptosome	3	396	1	2	0	2	553	0.65	0.01	0.00	2.1
328	203615	eNOS activation	3	396	1	2	0	2	553	0.65	0.01	0.00	2.1
329	hsa00240	Pyrimidine metabolism - Homo sapiens (human)	3	396	2	1	1	2	553	0.65	0.01	0.00	2.1
330	199418	Negative regulation of the PI3K/AKT network	3	396	1	2	0	2	553	0.65	0.01	0.00	2.1
331	203765	eNOS activation and regulation	3	396	1	2	0	2	553	0.65	0.01	0.00	2.1
332	198753	ERK/MAPK targets	3	396	1	2	0	2	553	0.65	0.01	0.00	2.1
333	hsa04540	Gap junction - Homo sapiens (human)	11	388	7	4	9	13	542	0.68	0.03	0.02	1.2
334	162587	HIV Life Cycle	3	396	2	1	2	3	552	0.70	0.01	0.01	1.4
335	74226	ATP formation	3	396	1	2	1	3	552	0.70	0.01	0.01	1.4
336	111463	SMAC binds to IAPs	3	396	1	2	1	3	552	0.70	0.01	0.01	1.4
337	109704	PI3K Cascade	3	396	1	2	1	3	552	0.70	0.01	0.01	1.4
338	114452	Activation of BH3-only proteins	3	396	0	3	0	3	552	0.70	0.01	0.01	1.4
339	111469	SMAC-mediated apoptotic response	3	396	1	2	1	3	552	0.70	0.01	0.01	1.4
340	111464	SMAC-mediated dissociation of IAP:caspase complexes	3	396	1	2	1	3	552	0.70	0.01	0.01	1.4
341	75983	Formation and Maturation of mRNA Transcript	2	397	1	1	4	5	550	0.71	0.01	0.01	0.6
342	196849	Metabolism of water-soluble vitamins and cofactors	2	397	1	1	4	5	550	0.71	0.01	0.01	0.6
343	196854	Metabolism of vitamins and cofactors	2	397	1	1	4	5	550	0.71	0.01	0.01	0.6
344	194315	Signaling by Rho GTPases	4	395	2	2	2	4	551	0.73	0.01	0.01	1.4
345	111459	Activation of caspases through apoptosome-mediated cleavage	4	395	1	3	1	4	551	0.73	0.01	0.01	1.4
346	hsa00220	Urea cycle and metabolism of amino groups - Homo sapiens (human)	4	395	3	1	3	4	551	0.73	0.01	0.01	1.4
347	75157	FasL/ CD95L signaling	4	395	0	4	0	4	551	0.73	0.01	0.01	1.4
348	hsa00860	Porphyrin and chlorophyll metabolism - Homo sapiens (human)	4	395	0	4	0	4	551	0.73	0.01	0.01	1.4
349	111461	Cytochrome c-mediated apoptotic response	4	395	1	3	1	4	551	0.73	0.01	0.01	1.4
350	hsa04512	ECM-receptor interaction - Homo sapiens (human)	3	396	2	1	5	6	549	0.74	0.01	0.01	0.7
351	140191	Phase 1 functionalization	5	394	3	2	3	5	550	0.75	0.01	0.01	1.4
352	74231	Purine biosynthesis	5	394	1	4	1	5	550	0.75	0.01	0.01	1.4
353	111471	Apoptotic factor-mediated response	5	394	1	4	1	5	550	0.75	0.01	0.01	1.4
354	109581	Apoptosis	19	380	4	15	9	24	531	0.75	0.05	0.04	1.1
355	hsa04110	Cell cycle - Homo sapiens (human)	6	393	5	1	6	7	548	0.78	0.02	0.01	1.2
356	hsa04510	Focal adhesion - Homo sapiens (human)	28	371	11	17	19	36	519	0.79	0.07	0.06	1.1
357	168898	Toll Receptor Cascades	8	391	3	5	5	10	545	0.81	0.02	0.02	1.1
358	168249	Innate Immunity Signaling	8	391	3	5	5	10	545	0.81	0.02	0.02	1.1
359	hsa05219	Bladder cancer - Homo sapiens (human)	10	389	6	4	8	12	543	0.83	0.03	0.02	1.2
360	hsa05040	Huntington's disease - Homo sapiens (human)	9	390	2	7	7	14	541	0.83	0.02	0.03	0.9
361	hsa04650	Natural killer cell mediated cytotoxicity - Homo sapiens (human)	16	383	5	11	10	21	534	0.87	0.04	0.04	1.1
362	168256	Signaling in Immune system	24	375	10	14	18	32	523	0.89	0.06	0.06	1.0
363	hsa04620	Toll-like receptor signaling pathway - Homo sapiens (human)	23	376	6	17	15	32	523	1.00	0.06	0.06	1.0
364	hsa04310	Wnt signaling pathway - Homo sapiens (human)	11	388	3	8	7	15	540	1.00	0.03	0.03	1.0
365	hsa04020	Calcium signaling pathway - Homo sapiens (human)	11	388	4	7	8	15	540	1.00	0.03	0.03	1.0
366	hsa04150	mTOR signaling pathway - Homo sapiens (human)	10	389	3	7	7	14	541	1.00	0.03	0.03	1.0
367	hsa05120	Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)	10	389	1	9	5	14	541	1.00	0.03	0.03	1.0
368	hsa04940	Type I diabetes mellitus - Homo sapiens (human)	10	389	1	9	4	13	542	1.00	0.03	0.02	1.1
369	hsa05010	Alzheimer's disease - Homo sapiens (human)	10	389	1	9	6	15	540	1.00	0.03	0.03	0.9
370	hsa04612	Antigen processing and presentation - Homo sapiens (human)	8	391	2	6	6	12	543	1.00	0.02	0.02	0.9
371	hsa00590	Arachidonic acid metabolism - Homo sapiens (human)	7	392	2	5	6	11	544	1.00	0.02	0.02	0.9
372	hsa04350	TGF-beta signaling pathway - Homo sapiens (human)	7	392	2	5	4	9	546	1.00	0.02	0.02	1.1
373	hsa04520	Adherens junction - Homo sapiens (human)	6	393	3	3	6	9	546	1.00	0.02	0.02	0.9
374	73887	Death Receptor Signalling	5	394	0	5	3	8	547	1.00	0.01	0.01	0.9
375	74159	Transcription	5	394	3	2	4	6	549	1.00	0.01	0.01	1.2
376	hsa05050	Dentatorubropallidoluysian atrophy (DRPLA) - Homo sapiens (human)	5	394	0	5	1	6	549	1.00	0.01	0.01	1.2
377	hsa04120	Ubiquitin mediated proteolysis - Homo sapiens (human)	5	394	2	3	4	7	548	1.00	0.01	0.01	1.0
378	109607	Extrinsic Pathway for Apoptosis	5	394	0	5	3	8	547	1.00	0.01	0.01	0.9
379	163359	Glucagon signaling in metabolic regulation	4	395	1	3	2	5	550	1.00	0.01	0.01	1.1
380	140534	Caspase-8 is formed from procaspase-8	4	395	0	4	2	6	549	1.00	0.01	0.01	0.9
381	hsa05130	Pathogenic Escherichia coli infection - EHEC - Homo sapiens (human)	4	395	2	2	4	6	549	1.00	0.01	0.01	0.9
382	hsa00330	Arginine and proline metabolism - Homo sapiens (human)	4	395	1	3	3	6	549	1.00	0.01	0.01	0.9
383	hsa05131	Pathogenic Escherichia coli infection - EPEC - Homo sapiens (human)	4	395	2	2	4	6	549	1.00	0.01	0.01	0.9
384	69416	Activation of Pro-Caspase 8	4	395	0	4	2	6	549	1.00	0.01	0.01	0.9
385	hsa00680	Methane metabolism - Homo sapiens (human)	3	396	1	2	2	4	551	1.00	0.01	0.01	1.0
386	195399	VEGF binds to VEGFR leading to receptor dimerization	3	396	0	3	2	5	550	1.00	0.01	0.01	0.8
387	194306	Neurophilin interactions with VEGF and VEGFR	3	396	0	3	2	5	550	1.00	0.01	0.01	0.8
388	75071	mRNA Processing	3	396	2	1	3	4	551	1.00	0.01	0.01	1.0
389	75893	TNF signaling	3	396	0	3	1	4	551	1.00	0.01	0.01	1.0
390	196836	Vitamin C (ascorbate) metabolism	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
391	hsa00960	Alkaloid biosynthesis II - Homo sapiens (human)	2	397	0	2	1	3	552	1.00	0.01	0.01	0.9
392	163210	Formation of ATP by chemiosmotic coupling	2	397	0	2	1	3	552	1.00	0.01	0.01	0.9
393	111807	Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
394	hsa00280	Valine, leucine and isoleucine degradation - Homo sapiens (human)	2	397	2	0	2	2	553	1.00	0.01	0.00	1.4
395	72163	mRNA Splicing - Major Pathway	2	397	1	1	2	3	552	1.00	0.01	0.01	0.9
396	hsa00910	Nitrogen metabolism - Homo sapiens (human)	2	397	0	2	1	3	552	1.00	0.01	0.01	0.9
397	111752	Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates by ribonucleotide reductase and thioredoxin	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
398	73857	RNA Polymerase II Transcription	2	397	1	1	3	4	551	1.00	0.01	0.01	0.7
399	187015	Activation of TRKA receptors	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
400	168254	Influenza Infection	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
401	hsa00100	Biosynthesis of steroids - Homo sapiens (human)	2	397	2	0	2	2	553	1.00	0.01	0.00	1.4
402	70171	Glycolysis	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
403	112295	Elongation and Processing of Capped Transcripts	2	397	1	1	3	4	551	1.00	0.01	0.01	0.7
404	157212	A third proteolytic cleavage releases NICD	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
405	74219	dGTP formation	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
406	114696	Thrombin-activated activation cascade	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
407	76043	Elongation of Intron-Containing Transcripts and co-transcriptional mRNA splicing	2	397	1	1	3	4	551	1.00	0.01	0.01	0.7
408	70268	Cori Cycle (interconversion of glucose and lactate)	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
409	hsa00564	Glycerophospholipid metabolism - Homo sapiens (human)	2	397	2	0	4	4	551	1.00	0.01	0.01	0.7
410	75815	Ubiquitin-dependent degradation of Cyclin D	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
411	72187	mRNA 3'-end processing	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
412	112296	Post-Elongation Processing of Intron-Containing pre-mRNA	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
413	164952	The role of Nef in HIV-1 replication and disease pathogenesis	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
414	69229	Ubiquitin-dependent degradation of Cyclin D1	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
415	114665	G-protein cascades	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
416	202433	Generation of second messenger molecules	2	397	0	2	1	3	552	1.00	0.01	0.01	0.9
417	hsa00940	Phenylpropanoid biosynthesis - Homo sapiens (human)	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
418	168927	Viral dsRNA:TLR3:TRIF Complex Activates RIP1	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
419	hsa04140	Regulation of autophagy - Homo sapiens (human)	2	397	0	2	2	4	551	1.00	0.01	0.01	0.7
420	192076	Steroid metabolism	2	397	1	1	2	3	552	1.00	0.01	0.01	0.9
421	112168	Processing of Capped pre-mRNA	2	397	1	1	2	3	552	1.00	0.01	0.01	0.9
422	70614	Aspartate, asparagine, glutamate, and glutamine metabolism	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
423	210990	PECAM1 interactions	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
424	198693	AKT phosphorylates targets in the nucleus	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
425	109688	Cleavage of Growing Transcript in the Termination Region	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
426	hsa00071	Fatty acid metabolism - Homo sapiens (human)	2	397	2	0	2	2	553	1.00	0.01	0.00	1.4
427	76044	Post-Elongation Processing of the Transcript	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
428	111447	Activation of BAD and translocation to mitochondria	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
429	73856	RNA Polymerase II Transcription Termination	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
430	72202	Transport of Mature Transcript to Cytoplasm	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
431	75158	TRAIL signaling	2	397	0	2	2	4	551	1.00	0.01	0.01	0.7
432	74230	dATP formation	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
433	hsa05217	Basal cell carcinoma - Homo sapiens (human)	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
434	111457	Release of apoptotic factors from the mitochondria	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
435	hsa05110	Cholera - Infection - Homo sapiens (human)	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
436	70895	Branched-chain amino acid catabolism	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
437	111804	Reduction of nuclear ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (thioredoxin)	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
438	72172	mRNA Splicing	2	397	1	1	2	3	552	1.00	0.01	0.01	0.9
439	hsa00640	Propanoate metabolism - Homo sapiens (human)	2	397	2	0	3	3	552	1.00	0.01	0.01	0.9
440	187024	NGF-independant TRKA activation	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
441	hsa04330	Notch signaling pathway - Homo sapiens (human)	2	397	0	2	2	4	551	1.00	0.01	0.01	0.7
442	hsa00760	Nicotinate and nicotinamide metabolism - Homo sapiens (human)	2	397	1	1	1	2	553	1.00	0.01	0.00	1.4
443	167021	PLC-gamma1 signalling	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
444	73648	Pyrimidine biosynthesis (interconversion)	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
445	111751	Reduction of cytosolic ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates (thioredoxin)	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
446	157118	Signaling by Notch	2	397	0	2	0	2	553	1.00	0.01	0.00	1.4
447	72203	Processing of Capped Intron-Containing Pre-mRNA	2	397	1	1	2	3	552	1.00	0.01	0.01	0.9
448	109970	Global Genomic NER (GG-NER)	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
449	hsa00550	Peptidoglycan biosynthesis - Homo sapiens (human)	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
450	166207	S6K1-mediated signalling	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
451	69610	p53-Independent DNA Damage Response	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
452	194068	Metabolism of bile acids and bile salts	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
453	72662	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
454	140180	COX reactions	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
455	199920	CREB phosphorylation	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
456	202427	Phosphorylation of CD3 and TCR zeta chains	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
457	74744	SHC activation	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
458	114592	Collagen adhesion via alpha 2 beta 1 glycoprotein	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
459	202430	Translocation of ZAP-70 to Immunological synapse	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
460	hsa00450	Selenoamino acid metabolism - Homo sapiens (human)	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
461	hsa00310	Lysine degradation - Homo sapiens (human)	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
462	190370	FGFR1b ligand binding and activation	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
463	70108	Glyceraldehyde 3-phosphate, NAD+, and orthophosphate react to form 1,3-bisphosphoglycerate, NADH, and H+	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
464	hsa00053	Ascorbate and aldarate metabolism - Homo sapiens (human)	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
465	166208	mTORC1-mediated signalling	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
466	112297	Post-Elongation Processing of Intronless pre-mRNA	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
467	70263	Gluconeogenesis	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
468	75108	Activation, myristolyation of BID and translocation to mitochondria	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
469	72695	Formation of the ternary complex, and subsequently, the 43S complex	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
470	74257	Xanthine formation	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
471	187042	TRKA activation by NGF	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
472	164938	Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
473	114508	Phospholipase-mediated signalling	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
474	167826	The fatty acid cycling model	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
475	177504	Retrograde neurotrophin signalling	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
476	114516	Disinhibition of SNARE formation	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
477	159234	Transport of Mature mRNAs Derived from Intronless Transcripts	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
478	72165	mRNA Splicing - Minor Pathway	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
479	74713	IRS activation	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
480	140187	P450 Prostaglandin isomerizations	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
481	159231	Transport of Mature mRNA Derived from an Intronless Transcript	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
482	hsa00624	1- and 2-Methylnaphthalene degradation - Homo sapiens (human)	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
483	72702	Ribosomal scanning and start codon recognition	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
484	180534	Vpu mediated degradation of CD4	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
485	165159	mTOR signalling	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
486	167590	Nef Mediated CD4 Down-regulation	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
487	164944	Nef and signal transduction	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
488	hsa00471	D-Glutamine and D-glutamate metabolism - Homo sapiens (human)	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
489	166187	Mitochondrial Uncoupling Proteins	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
490	114664	G alpha 12 cascade	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
491	69601	Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
492	70525	Alanine metabolism	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
493	69613	p53-Independent G1/S DNA damage checkpoint	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
494	114711	vWF interaction with collagen	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
495	hsa03022	Basal transcription factors - Homo sapiens (human)	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
496	69017	CDK-mediated phosphorylation and removal of Cdc6	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
497	190371	FGFR3b ligand binding and activation	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
498	72649	Translation initiation complex formation	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
499	114593	Collagen adhesion via Gp IV	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
500	hsa04742	Taste transduction - Homo sapiens (human)	1	398	1	0	2	2	553	1.00	0.00	0.00	0.7
501	68827	CDT1 association with the CDC6:ORC:origin complex	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
502	77595	Processing of Intronless Pre-mRNAs	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
503	hsa00130	Ubiquinone biosynthesis - Homo sapiens (human)	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
504	139910	Activation of BMF and translocation to mitochondria	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
505	112411	ERK2 activation	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
506	111446	Activation of BIM and translocation to mitochondria	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
507	hsa00970	Aminoacyl-tRNA biosynthesis - Homo sapiens (human)	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
508	75877	Conversion of Fatty Acyl-CoA to Phosphatidic Acid	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
509	77387	Insulin receptor recycling	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
510	109703	PKB-mediated events	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
511	74259	Purine catabolism	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
512	70793	Leucine catabolism	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
513	73854	RNA Polymerase I Promoter Clearance	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
514	73937	Transcription-coupled NER (TC-NER)	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
515	191273	Cholesterol biosynthesis	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
516	165720	S6K1 signalling	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
517	75109	Triacylglyceride Biosynthesis	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
518	75892	Platelet Adhesion to exposed collagen	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
519	159418	Recycling of bile acids and salts	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
520	190377	FGFR2b ligand binding and activation	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
521	73885	Nucleotide Excision Repair	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
522	114666	G alpha Q cascade	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
523	212718	EGFR interacts with phospholipase C-gamma	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
524	75067	Processing of Capped Intronless Pre-mRNA	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
525	191345	Transformation of lanosterol to cholesterol	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4
526	139943	PLC-mediated hydrolysis	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
527	hsa00232	Caffeine metabolism - Homo sapiens (human)	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
528	167827	The proton buffering model	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
529	111453	BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
530	198745	Signalling to STAT3	1	398	0	1	1	2	553	1.00	0.00	0.00	0.7
531	69298	Association of licensing factors with the pre-replicative complex	1	398	0	1	0	1	554	1.00	0.00	0.00	1.4
532	73864	RNA Polymerase I Transcription	1	398	1	0	1	1	554	1.00	0.00	0.00	1.4

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