HUGO ID Detailed Result 7808

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
9086508	NGF	NGF	1.2	Neurotrophic factors (NTFs) NTFs such as nerve growth factor (NGF), NGF brain-derived neurotrophic factor (BDNF) BDNF and ciliary neurotrophic factor (CNTF)
9086508	NGF	NGF	1.2	It is apparent that both NGF and BDNF induce a range of adverse effects for example
9086508	NGF	NGF	1.2	It has been demonstrated that NGF induces release of biologically active mediators such as histamine from
9086508	NGF	NGF	1.2	NTFs with a rank order of BDNF > CNTF > NGF in contrast RPMC were refractory to the effects of BDNF
11173059	NGF	NGF	1.2	The trophic activity of nerve growth factor (NGF) NGF on cholinergic basal forebrain neurons ( Scott and Crutcher 1994
11173059	NGF	NGF	1.2	NGF levels are increased in cortical areas of brains from patients
11173059	NGF	NGF	1.2	patients with established Alzheimer disease whereas the number of high-affinity NGF receptors is decreased in the basal forebrain ( Hock et
11173059	NGF	NGF	1.2	number of high-affinity trkA receptors might mediate the loss of NGF trophic activity through impaired retrograde axonal transport ( Mufson et
11173059	NGF	NGF	1.2	Furthermore indirect but compelling evidence in favor of NGF involvement in the pathogenesis of Alzheimer disease comes from a
11173059	NGF	NGF	1.2	Because of the inability of NGF to cross the blood_amp_#x2013 brain barrier NGF-mimetic drugs (e.g., e.g.
11173059	NGF	NGF-mimetic	1.2	the inability of NGF to cross the blood_amp_#x2013 brain barrier NGF-mimetic drugs (e.g., e.g. Neotrofin or AIT-082 have been engineered and
15210305	NGF	NGF	0.6	In addition RA potentiates the protective effect of NGF in a model of stautosporine-induced apoptosis in cultured chick neurones
15572176	NGF	NGF	1.2	astrocytes secrete pro-apoptotic mediators such as nerve growth factor (NGF) NGF or Fas-ligand a mechanism that may serve to eliminate vulnerable
15572176	NGF	NGF	1.2	factors produced by activated astrocytes such as FasL TNF-_amp_#x3b1 and NGF are capable of activating death receptors expressed in the diseased
15572176	NGF	NGF	1.2	apoptotic candidate released by astrocytes is nerve growth factor (NGF) NGF
15572176	NGF	NGF	1.2	Clearly NGF is critical for the differentiation and survival of specific neuronal
15572176	NGF	NGF	1.2	While NGF can signal through activation of the high affinity TrkA receptor
15572176	NGF	NGF	1.2	Motor neurons are generally thought to be unresponsive to NGF because they lack the specific TrkA receptor
15572176	NGF	NGF	1.2	in chronic active MS lesions suggesting an additional role for NGF in regulating the immune response in glial cells 135
15572176	NGF	NGF	1.2	expression and release of several growth factors and cytokines including NGF 33
15572176	NGF	NGF	1.2	Increased NGF levels have been shown in rodent CNS following experimental lesions
15572176	NGF	NGF	1.2	Expression of NGF receptors in active multiple sclerosis lesions suggests a role for
15572176	NGF	NGF	1.2	receptors in active multiple sclerosis lesions suggests a role for NGF in regulating the autoimmune response at both immune and glial
15572176	NGF	NGF	1.2	However little is known about the expression of NGF in ALS although increased NGF levels were reported in muscle
15572176	NGF	NGF	1.2	known about the expression of NGF in ALS although increased NGF levels were reported in muscle of ALS patients 72 and
15572176	NGF	NGF	1.2	Thus it is conceivable that NGF signaling between astrocytes and p75 NTR -expressing motor neurons may
15572176	NGF	NGF	1.2	We have recently found a prominent increase in NGF immunoreactivity in the neuropil of the anterior horn in symptomatic
15572176	NGF	NGF	1.2	p75 NTR expression in motor neurons 93 suggesting that increased NGF production may parallel the development of astrocytosis in ALS and
15572176	NGF	NGF	1.2	also found that reactive astrocytes secrete high molecular forms of NGF which could correspond to the precursors forms of NGF (pro-NGF)
15572176	NGF	NGF	1.2	of NGF which could correspond to the precursors forms of NGF (pro-NGF) pro-NGF 92
15572176	NGF	NGF	1.2	Two recent reports further support a role for a NGF/p75 NGF p75 NTR apoptotic pathway in ALS
15572176	NGF	NGF	1.2	Similarly increased production of either FasL or NGF does not induce motor neuron apoptosis unless nitric oxide is
15572176	NGF	NGF	1.2	by producing NO cytokines and pro apoptotic mediators such as NGF or FasL
16624536	NGF	NGF	1.2	79 and neurotrophic factors (e.g., e.g. plasminogen TGF-_amp_#x3b2 bFGF BDNF NGF NT-3 and NT-4 80 81 and 82
16624536	NGF	NGF	1.2	significant suppression of the extent of both microglial proliferation and NGF up-regulation is observed 85
16624536	NGF	NGF	1.2	FGFR1 in astrocytic nuclei and stimulates nerve growth factor (NGF) NGF expression and secretion by astrocytes 117
16624536	NGF	NGF	1.2	This NGF production has been previously shown to induce motor neuron apoptosis
17015226	NGF	NGF	0.6	astrocytes induce embryonic motor neuron degeneration via their production of NGF which in the presence of low concentrations of nitric oxide
17015226	NGF	NGF	0.6	in the spinal cord of hSOD1 G93A mice have increased NGF synthesis ( Pehar et_amp_#xa0 al. 2004
17191135	NGF	NGF	0.6	Recent work suggests that Trx-1 play a key role in NGF signaling pathways 74
17191135	NGF	NGF	0.6	NGF a neurotrophic factor regulating development maintenance and function of the
17418957	NGF	NGF	0.3	by positive selection immuno-panning using antibody against the low-affinity p75 NGF receptor (192 192 antibody was a gift of the E
17896980	NGF	NGF	1.2	Nerve growth factor (NGF) NGF and brain-derived neurotrophic factor (BDNF) BDNF belong to the protein
17896980	NGF	NGF	1.2	Moreover NGF and BDNF are known to modulate immune cell function and
17896980	NGF	NGF	1.2	an overview of the pathophysiology therapeutic interventions and strategies concerning NGF and BDNF in the mentioned diseases
18464925	NGF	NGF	1.2	synthesis and release of neurotrophic factor nerve growth factor (NGF) NGF in mouse primary astrocytes which could further contribute to neuroprotection
9086508	nerve growth factor	nerve growth factor	1.0	neurotrophic factors ntfs such as nerve growth factor ngf brain derived neurotrophic factor bdnf and ciliary neurotrophic factor cntf are currently being explored as novel therapeutics in a range of neurodegenerative disorders such as amyotrophic latera
11173059	nerve growth factor	nerve growth factor	1.0	the trophic activity of nerve growth factor ngf on cholinergic basal forebrain neurons scott and crutcher 1994 the main population of nerve cells that degenerate in alzheimer disease indicated that neurotrophic factors could play a primary rol
15081582	nerve growth factor	nerve growth factor	1.0	in addition pge 1 also derived from pge 2 reduces the incidence of apoptotic death in nerve growth factor deprived pheochromocytoma pc12 cells by preventing the activation of apoptotic signals through blocking the activation of stress activated protein kinase sapk /c jun n terminal kinase jnk kawamura et
15572176	nerve growth factor	nerve growth factor	1.0	in addition reactive astrocytes secrete pro apoptotic mediators such as nerve growth factor ngf or fas ligand a mechanism that may serve to eliminate vulnerable motor neurons.
15572176	nerve growth factor	nerve growth factor	1.0	another potential apoptotic candidate released by astrocytes is nerve growth factor ngf .
16624536	nerve growth factor	nerve growth factor	1.0	fibroblast growth factor 1 fgf 1 released from motor neurons in response to injury or oxidative stress leads to accumulation of fgf receptor 1 fgfr1 in astrocytic nuclei and stimulates nerve growth factor ngf expression and secretion by astrocytes [117] .
16766086	nerve growth factor	nerve growth factor	1.0	interestingly nerve growth factor was shown to increase the expression and activity of ppar_amp_#x3b3; in sympathetic neuron like pc12 cells fuenzalida et al. 2005 and noradrenaline exposure increased ppar_amp_#x3b3; levels in neuron
17896980	nerve growth factor	nerve growth factor	1.0	nerve growth factor ngf and brain derived neurotrophic factor bdnf belong to the protein family of neurotrophins.
18464925	nerve growth factor	nerve growth factor	1.0	finally 15d pgj 2 remarkably increase the synthesis and release of neurotrophic factor nerve growth factor ngf in mouse primary astrocytes which could further contribute to neuroprotection [ 57 ].