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| 14960605 | NF-kappaB | NF-kappaB | 0.6 | et al. 2001 kappaB alpha inhibitory protein of nuclear factor-kappaB NF-kappaB (index index of NF-kappaB activity tumor necrosis factor-alpha TNF-alpha and | |  |
| 14960605 | NF-kappaB | NF-kappaB | 0.6 | alpha inhibitory protein of nuclear factor-kappaB NF-kappaB (index index of NF-kappaB activity tumor necrosis factor-alpha TNF-alpha and CD14 (data data not | |  |
| 15081582 | NF-kappaB | NF-kappaB | 0.3 | expression that is prevented in the presence of inhibitors of NF-kappaB (dexamethasone, dexamethasone the antioxidant pyrrolidine dithiocarbamate and the protein C | |  |
| 15668976 | NF-kappaB | NF-kappaB | 0.0 | -9 were upregulated whereas cell death inhibitors acetyl-CoA transporter and NF-kappaB were also upregulated | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | dithiocarbamate (PDTC), PDTC an inhibitor of nuclear transcription factor kappa-B NF-kappaB and an antioxidant has beneficial effects in animal models of | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | The DNA binding activity of NF-kappaB was not altered in G93A-SOD1 TG rats by PDTC treatment | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | the treatment of AIDS (Reisinger Reisinger et al. 1990 kappa-B NF-kappaB that regulates the expression of several proinflammatory genes and some | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | NF-kappaB activation may promote the expression of the genes that mediate | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | cord samples showed no differences in DNA binding activity of NF-kappaB between PDTC and untreated groups ( Fig 2 | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | there was a trend toward increased DNA binding activity of NF-kappaB in G93A-SOD1 TG rats | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | peripheral disease models by inhibiting the activation of transcription factor NF-kappaB serving as a strong antioxidant or by activating Akt-GSK3 beta | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | Even though inhibition of NF-kappaB has frequently been associated with tissue and cellular protection inhibition | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | frequently been associated with tissue and cellular protection inhibition of NF-kappaB may also accelerate neurodegeneration because of the survivalsupporting role of | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | is possible that in a long-term disease such as ALS NF-kappaB activity even though being induced is not maintained at so | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | does and thereby does not result in efficient inhibition of NF-kappaB In addition we cannot exclude the possibility that NF-kappaB binding | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | of NF-kappaB In addition we cannot exclude the possibility that NF-kappaB binding to DNA is increased at time points other than | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | experiments do not provide evidence for a central role of NF-kappaB in ALS | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | In a previous study NF-kappaB immunoreactivity was found to be increased in astrocytes surrounding degenerating | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | multipotent drug providing protection in various animal models by inhibiting NF-kappaB acting as an antioxidant and activating Akt-GSK3 beta pathway also | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | showed no statistically significant differences in DNA binding activity of NF-kappaB between PDTC and untreated groups n = 5 results shown | |  |
| 17008387 | NF-kappaB | NF-kappaB | 0.6 | dithiocarbamate ALS amyotrophic lateral sclerosis EMSA electrophoretic mobility shift assay NF-kappaB nuclear factor kappaB SOD superoxide dismutase WT wild type TG | |  |
| 17191135 | NFKB | NFkB | 0.6 | Fos/Jun Fos Jun activator protein-1 (AP-1)], AP-1 nuclear factor-kB (NFkB) NFkB and the more recently identified Nrf2 proteins 24 -26 (Fig | |  |
| 17191135 | NF-kB | NF-kB | 0.6 | conferring constitutive expression inducible expression elements such as AP-1 AP-2 NF-kB Oct-1 PEA-3 Myb and the antioxidant-responsive element (ARE) ARE 71 | |  |
| 17191135 | NF-kB | NF-kB | 0.6 | of critical transcription factors such as the AP-1 family members NF-kB Jun Fos p53 CREB PEBP2/CBF, PEBP2 CBF Myb all involved | |  |
| 17969353 | NF-kappaB | NF-kappaB | 0.5 | upregulated whereas cell death inhibitors acetyl-CoA transporter (ACATN) ACATN and NF-kappaB (NFKB) NFKB were also upregulated | |  |
| 17969353 | NFKB | NFKB | 0.5 | cell death inhibitors acetyl-CoA transporter (ACATN) ACATN and NF-kappaB (NFKB) NFKB were also upregulated | |  |
| 18312546 | NF-kappaB | NF-kappaB | 0.6 | protein kinase (p-p38) p-p38 and inhibitor of nuclear factor-kappaB (NF-kappaB)-alpha NF-kappaB -alpha (IkappaBalpha) IkappaBalpha in the spinal cords and compared the | |  |
| 18312546 | NF-kappaB | NF-kappaB-mediated | 0.6 | that pioglitazone protects motor neurons against p38-mediated neuronal death and NF-kappaB-mediated glial inflammation via a PPARgamma-independent mechanism | |  |
| 14511332 | nf kappa b | nf kappa b | 1.0 | nf kappa b. nf kappa b in particular is crucial for cox 2 induction in several cell types vane et al . 1998 and its activation has also been linked to neurodegeneration grilli _amp_ memo 1999 . | |  |
| 15210305 | nf kappa b | nf kappa b | 1.0 | immunohistochemical expression of a number of gene candidates including c jun jnk/sapk a kinase that exerts a stress related activation of c jun and nf kappa b a transcription factor induced by oxidative injury with a prominent neuroprotective function have been assayed in different disease targeted tissues. | |  |
| 15210305 | nf kappa b | nf kappa b | 1.0 | the jnk/sapk c jun pathway was found to be markedly up regulated [ 67 ] in als spinal cord astrocytes together with nf kappa b whereas motor neurones show a lower expression of these molecules. | |  |
| 15649489 | nf kappa b | nf kappa b | 1.0 | nf kappa b|neuroprotective agents|ppar gamma|thiazolidinediones|pioglitazone|3 nitrotyrosine|tyrosine|nitric oxide synthase|nitric oxide synthase type ii|nos2 protein mouse|sod1 g93a protein|superoxide dismutas | |  |
| 17008387 | nf kappa b | nf kappa b | 1.0 | the effect of pdtc was not mediated through nf kappa b inhibition. | |  |
| 18464922 | nuclear factor kappa-b | nuclear factor kappa b | 1.0 | several anti inflammatory mechanisms have been suggested including inhibition of nuclear factor kappa b nf _amp_#x003ba; b activator protein 1 ap 1 in addition to signal transducers and activators of transcription stat transcription factors by ppar _amp_#x003b3; [ 31 ]. | |  |