HUGO ID Detailed Result 6081

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
15572176	insulin	insulin	1.0	further evidence for a role for motor neurons modulating astrocytes reactivity was provided in g93a sod 1 mice expressing increased levels of insulin growth factor 1 igf 1 in spinal motor neurons and skeletal muscle [ 67 ].
15649489	insulin	insulin	1.0	ppars have been implicated in insulin sensitivity adipocyte differentiation and inflammatory processes.
15657392	insulin	insulin	1.0	as its name implies igf 1 is similar to insulin in structure.
15657392	insulin	insulin	1.0	the mature igf 1 is a single chain protein of 70 aa and differs from insulin by retention of the c domain by a short extension of the a domain to include a novel domain d and by the presence of variable cooh terminal extension peptides e peptides; fig s1 .
16104843	insulin	insulin	1.0	rip1 tag2 t antigen 2 mice develop islet tumours of the pancreas by 12 14 weeks of age as a result of expression of the sv40 tag oncogene in insulin producing b cells.
16120782	insulin	insulin	1.0	peroxisome proliferator activated receptor gamma ppar gamma ligands were developed as oral antidiabetic drugs after the discovery that ppar gamma activation increases insulin sensitivity and normalizes serum glucose levels berger and moller 2002 gamma activators of the thiazolidinedione tzd class of antidiabetic drugs.
16120782	insulin	insulin	1.0	beyond their insulin sensitizing and other metabolic actions ppar gamma ligands exert several other ppar gamma dependent and independent antineoplastic and anti inflammatory effects daynes and jones 2002 ; blanquart et a
16120782	insulin	insulin	1.0	the drugs act to enhance insulin sensitivity and normalize blood glucose levels patsouris et al. 2004 gamma in enhancing muscle strength and preserving neuronal integrity and function might also arise from improved glucose utilizati
16766086	insulin	insulin	1.0	ppar_amp_#x3b3; agonists act principally in adipose tissue to stimulate fatty acid metabolism sensitize tissues to insulin action and modulate blood glucose levels.
16766086	insulin	insulin	1.0	specifically they postulate that rosiglitazone improves insulin sensitivity and suppresses serum corticosteroid levels in the transgenic animals.
16766086	insulin	insulin	1.0	an nih sponsored trial is currently testing the ability of pioglitazone to decrease stroke incidence in non diabetic patients with insulin resistance.
17018025	insulin	insulin	1.0	the cells were resuspended in the l 15 culture medium supplemented with sodium bicarbonate 0.2% glucose 3.6 mg/ml progesterone 20 n m insulin 5 _amp_#x03bc;g/ml putrescine 0.1 m m conalbumin 0.1 mg/ml sodium selenite 30 n m penicillin 100 iu/ml streptomycin 100 _amp_#x03bc;g/ml and horse serum 2% .
17418957	insulin	insulin	1.0	vitrogen 10 ng/ml each of bdnf cntf and gdnf peprotech rocky hill nj usa 100 _amp_#x3bc;g/ml transferrin 60 ng/ml progesterone 16 _amp_#x3bc;g/ml putrescine 40 ng/ml sodium selenite 5 _amp_#x3bc;g/ml insulin 1 mm sodium pyruvate 2 mm l glutamine 40 ng/ml triiodo thyronine 1 _amp_#x3bc;g/ml laminin 2.2 _amp_#x3bc;g/ml isobutylmethylxanthine 417 ng/ml forskolin 5 _amp_#x3bc;g/ml n acetyl cysteine 100 u/ml
17555556	insulin	insulin	1.0	the cells were then re suspended in the l 15 culture medium supplemented with sodium bicarbonate 0.2% glucose 3.6 mg/ml progesterone 20 nmol/l insulin 5 _amp_#x03bc;g/ml putrescine 0.1 mmol/l conalbumin 0.1 mg/ml sodium selenite 30 nmol/l penicillin 100 iu/ml streptomycin 100 _amp_#x03bc;g/ml and horse serum 2% .
17569578	insulin	insulin	1.0	the ability of ppar agonists to elicit anti amyloidogenic anti inflammatory and insulin sensitizing effects may account for the observed effects.
17569578	insulin	insulin	1.0	the reduced a_amp_#x3b2; 1_amp_#x2013;42 was argued to arise from an increase in the levels of insulin degrading enzyme ide in rosiglitazone treated transgenic mice.
17569578	insulin	insulin	1.0	these data were interpreted as evidence for a significant role for peripheral insulin sensitivity in cognition.
17569578	insulin	insulin	1.0	ad risk and memory impairment is associated with hyperinsulinemia and insulin resistance features which characterize type ii diabetes [110] and [170] .
17569578	insulin	insulin	1.0	these linkages led to the initiation of clinical investigations of insulin sensitizing tzds currently in clinical use for the treatment of type ii diabetes.
17569578	insulin	insulin	1.0	an nih sponsored trial is currently testing the ability of pioglitazone to decrease stroke incidence in non diabetic patients with insulin resistance.
18464922	insulin	insulin	1.0	rosiglitazone a ppar _amp_#x003b3; agonist that induces sensitization to insulin was tested in r6/2 transgenic mouse model of hd for the treatment of atypical diabetes in these mice [ 61 ].
18464922	insulin	insulin	1.0	the effect of glibenclamide a sulfonylurea that depolarizes pancreatic beta cells by blocking atp sensitive potassium channels to induce exocytosis of insulin leading to increase in insulin levels was also tested in r6/2 mice.
18464922	insulin	insulin	1.0	metformin has numerous effects on metabolism including insulin sensitization [ 63 ] increased glucose uptake [ 64 ] decrease hepatic glucose synthesis [ 65 ] activation of amp activated protein kinase ampk an enzyme involved in glucose and fatty acid metabolism
18464922	insulin	insulin	1.0	metformin was also considered to be effective in r6/2 mice because of its ability to sensitize insulin which leads to facilitation of glucose utilization.
18464922	insulin	insulin	1.0	studies in patients treated with ppar _amp_#x003b3; agonists indicate that the reduction of insulin resistance is resulted from the activation of ppar _amp_#x003b3; [ 78 ].
18464925	insulin	insulin	1.0	ir role in the regulation of genes involved in lipid and carbohydrate metabolism ppar _amp_#x003b3; and the other two isoforms ppar _amp_#x003b1; and _amp_#x003b4; deeply affect lipid homeostasis and insulin sensitivity [ 1 _amp_#x02013; 3 ].
18464925	insulin	insulin	1.0	a major group of synthetic ppar _amp_#x003b3; agonists is represented by the antidiabetic drugs tzds originally identified for their ability to improve the insulin sensitivity of diabetic animals.