Current Target Information
| HUGO ID | 4571 |
|---|---|
| Symbol | GRIA1 |
| Name | glutamate receptor, ionotropic, AMPA 1 |
| #Occurrence | 16 |
| #Paper | 8 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 14739060 | Neurodegenerative diseases and oxidative stress. | 33 | | Biomed Pharmacother |
| 17956327 | Respiratory plasticity following intermittent hypoxia: roles of protein phosphatases and reactive oxygen species. | 13 | | Biochem Soc Trans |
| 9745361 | Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? | 9 | | Trends Pharmacol Sci |
| 10627601 | AMPA exposures induce mitochondrial Ca(2+) overload and ROS generation in spinal motor neurons in vitro. | 5 | | J Neurosci |
| 12684448 | Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons. | 5 | | J Neurosci |
| 11513882 | Superoxide dismutase mutations of familial amyotrophic lateral sclerosis and the oxidative inactivation of calcineurin. | 4 | | FEBS Lett |
| 16764863 | BMAA selectively injures motor neurons via AMPA/kainate receptor activation. | 4 | | Exp Neurol |
| 17719032 | Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS. | 4 | | Exp Neurol |