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| 12909279 | COX2 | COX2 | 1.3 | proteins such as nitric oxide synthase (NOS) NOS 93 and COX2 70 that might be involved in mechanisms of inflammation-mediated neurodegeneration | Junguk Hur |  |
| 12909279 | COX2 | COX2 | 1.3 | Indeed COX2 and NOS activity are dramatically increased in post-mortem spinal cord | Junguk Hur |  |
| 12909279 | COX2 | COX2 | 1.3 | Increased levels of COX2 and of the pro-inflammatory prostaglandin PGE2 were found in the | Junguk Hur |  |
| 12909279 | COX2 | COX2 | 1.3 | Treatment with a selective COX2 inhibitor markedly inhibits production of PGE2 in the spinal cord | Junguk Hur |  |
| 14698606 | COX-2 | COX-2 | 1.0 | role for inflammation inhibitors of the enzyme cyclooxygenase 2 (COX-2) COX-2 have shown beneficial effects in SOD1 mutant mouse models 49 | |  |
| 12909279 | cox 2 | cox2 | 1.0 | nf _amp_#x3ba;b modulates the expression of several proteins such as nitric oxide synthase nos [ 93 ] and cox2 [ 70 ] that might be involved in mechanisms of inflammation mediated neurodegeneration and be crucial in the pathogenesis of als. | |  |
| 12909279 | cox 2 | cox2 | 1.0 | indeed cox2 and nos activity are dramatically increased in post mortem spinal cord samples from sporadic als patients and in astrocytes from fals mice [ 2 and 15 ]. | |  |
| 12909279 | cox 2 | cox2 | 1.0 | increased levels of cox2 and of the pro inflammatory prostaglandin pge2 were found in the cerebrospinal fluid from als patients [ 3 ]. | |  |
| 12909279 | cox 2 | cox2 | 1.0 | treatment with a selective cox2 inhibitor markedly inhibits production of pge2 in the spinal cord of als mice protecting motor neurones and significantly prolonging survival [ 23 ]. | |  |
| 14698606 | cox 2 | cox 2 | 1.0 | supporting a role for inflammation inhibitors of the enzyme cyclooxygenase 2 cox 2 have shown beneficial effects in sod1 mutant mouse models [ 49 and 50 ]. | |  |