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| 10643818 | PS1 | PS1 | 0.9 | Presenilins (PS1 PS1 and PS2 contribute to the regulation of apoptosis with the | |  |
| 14739060 | PSEN1 | PSEN1 | 0.9 | _amp_#x3b2 -amyloid precursor protein as well as presenilin 1 (PSEN1) PSEN1 and presenilin 2 (PSEN2) PSEN2 | | |
| 10643818 | presenilin 1 | presenilin 1 | 1.0 | known genetic risk factors for familial alzheimer's disease have been localized to the amyloid precursor protein apolipoprotein e presenilin 1 and presenilin 2 genes. | | |
| 10742195 | presenilin 1 | presenilin 1 | 1.0 | familial ad linked mutations of amyloid precursor protein app presenilin 1 and presenilin 2 increase both cerebral a_amp_#x3b2; burden and a_amp_#x3b2;1 42 production underscoring the role that a_amp_#x3b2; metabolism plays in ad pathogenesis see [ 10 ] . | | |
| 12663085 | presenilin 1 | presenilin 1 | 1.0 | m_amp_#xfc;nch et al. reported that the accumulation of intracellular age was observed in up to 95% of pyramidal neurons in patients with presenilin 1 mutations [ 60 ]. | | |
| 14739060 | presenilin 1 | presenilin 1 | 1.0 | in familial forms missense mutation have been identified for gene encoding _amp_#x3b2; amyloid precursor protein as well as presenilin 1 psen1 and presenilin 2 psen2 . | | |
| 16194581 | presenilin 1 | presenilin 1 | 1.0 | amyloid precursor protein/presenilin 1 app/psl transgenic mice have been used as a murine model for ad since these mutations facilitate the production of beta amyloid and consequently alzheimer like plaques in several regions of the brain | | |