HUGO ID Detailed Result 8768

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
16046141	AIF	AIF	0.6	For cytochrome c and AIF release experiments ETNA cells were harvested in hypotonic buffer (2
16046141	AIF	AIF	0.6	that other mitochondrial factors involved in apoptotic pathways such as AIF ( Fig 4 and Fig 5 and EndoG (not not
16046141	AIF	AIF	0.6	pore causing leakage of cytochrome c and apoptosis-inducing factor (AIF) AIF ( Friedlander 2003 were suggested to play a role in
16046141	AIF	AIF	0.6	mutants were assessed for the presence of cytochrome c and AIF by Western blot
16046141	AIF	AIF	0.6	untransfected ETNA cells were used as a positive control for AIF and cytochrome c expression
16046141	AIF	AIF	0.6	Fig 5._amp_#xa0 ETNA cells retain mitochondrial AIF upon fALS-SOD1 expression
16046141	AIF	AIF	0.6	confocal immunofluorescence microscopy staining of cytochrome c (green) green and AIF (red) red in ETNA cells 48 h after transfection with
16050975	AIF	AIF	0.6	pro-apoptotic factors such as cytochrome c apoptosis inducing factor (AIF), AIF and endoG from individual mitochondria perhaps in response to local
17150307	AIF	AIF	0.6	of GSH decreased mitochondrial function facilitated apoptosis inducing factor (AIF) AIF translocation cytochrome c release and caspase 3 activation and consequently
17150307	AIF	AIF	0.6	the spinal cord and motor neuron cells is correlated with AIF translocation caspase 3 activation and motor neuron degeneration during ALS-like
17150307	AIF	AIF	0.6	Western analysis was performed to analyze cytochrome c release and AIF translocation
17150307	AIF	AIF	0.6	incubated with specific antibodies overnight at 4 _amp_#x000b0 C (AIF, AIF cytochrome c and active caspase 3 antibodies were all at
17150307	AIF	AIF	0.6	Results GSH depletion promoted AIF redistribution cytochrome c release caspase 3 activation and apoptotic cell
17150307	AIF	AIF	0.6	nuclear fractionations coupled with western analysis showed an increase of AIF translocation to nucleus following GSH depletion in NSC34 cells (
17150307	AIF	AIF	0.6	Immunohistochemical staining confirmed the increase of AIF translocation to the nucleus from the mitochondria upon GSH depletion
17150307	AIF	AIF	0.6	Decreased GSH was associated with AIF nuclear translocation caspase 3 activation and motor neuron cell death
17150307	AIF	AIF	0.6	Reduction in GSH was associated with redistribution of AIF from mitochondria to nuclei 3
17150307	AIF	AIF	0.6	cell death mechanisms potentially induced by GSH depletion we assessed AIF redistribution and found that there was an increase in AIF
17150307	AIF	AIF	0.6	AIF redistribution and found that there was an increase in AIF translocation from mitochondria to nuclei upon GSH depletion ( Figure
17150307	AIF	AIF	0.6	AIF is a flavoprotein residing in mitochondrial intermembrane ( Cande et
17150307	AIF	AIF	0.6	Translocation of AIF initiates cell apoptosis by cleavage internucleosomal DNA to relative large
17150307	AIF	AIF	0.6	AIF nuclear translocation has been observed in a variety of cell
17150307	AIF	AIF	0.6	The AIF redistribution detected in EA treated cells and also observed in
17150307	AIF	AIF	0.6	coupled with increased oxidative stress by mutant G93A-SOD1 that facilitates AIF nuclear translocation may underlie some of the events linked to
17150307	AIF	AIF	0.6	Figure 9 Redistribution of AIF and active caspase 3 in motor neuron cells of ALS-like
17150307	AIF	AIF	0.6	AIF Apoptosis Inducing Factor ALS Amyotrophic Lateral Sclerosis BSO L-Buthionine Sulfoximine
14739060	apoptosis-inducing factor	apoptosis inducing factor	1.0	hen it is released from the mitochondria into cytoplasm trigger the caspase chain _amp_#x2022; smac/diablo binds to inhibitors of activated caspases and causes further caspase activation _amp_#x2022; apoptosis inducing factor and endonuclease g mediate caspase independent cell death pathways
16046141	apoptosis-inducing factor	apoptosis inducing factor	1.0	leading to bioenergetic failure in the motor neurons bendotti et al. 2001 and jung et al. 2002 and to alteration in the mitochondrial permeability transition pore causing leakage of cytochrome c and apoptosis inducing factor aif friedlander 2003 were suggested to play a role in the mitochondrial dependent motor neuron death through the activation of a caspase mediated cascade leading to programmed cell death.
16050975	apoptosis-inducing factor	apoptosis inducing factor	1.0	one may envision a scenario where mitochondrial dysfunction results in quantal releases of pro apoptotic factors such as cytochrome c apoptosis inducing factor aif and endog from individual mitochondria perhaps in response to local calcium mediated toxicity for example under excitatory synapses.
16242643	apoptosis-inducing factor	apoptosis inducing factor	1.0	this blockade in turn inhibits the release of the proapoptotic factors cytochrome c smac diablo and apoptosis inducing factor from the mitochondria wang et al. 2003 and zhu et al. 2002 .
17099894	apoptosis-inducing factor	apoptosis inducing factor	1.0	the mn death is independent of activation of caspases 1 3 and 8 or apoptosis inducing factor within mns with a blockade of apoptosis possibly mediated by aven up regulation.
17150307	apoptosis-inducing factor	apoptosis inducing factor	1.0	furthermore depletion of gsh decreased mitochondrial function facilitated apoptosis inducing factor aif translocation cytochrome c release and caspase 3 activation and consequently led to motor neuron like cell apoptosis.
17150307	apoptosis-inducing factor	apoptosis inducing factor	1.0	aif apoptosis inducing factor als amyotrophic lateral sclerosis bso l buthionine sulfoximine dcf dichlorofluorescin dmem dulbecco_amp_#x02019;s modified eagle_amp_#x02019;s medium ea ethacrynic acid fbs fetal bovine serum _amp_#x
17150307	apoptosis-inducing factor	apoptosis inducing factor	1.0	apoptosis inducing factor|biological markers|enzyme inhibitors|reactive oxygen species|buthionine sulfoximine|ethacrynic acid|glutathione|superoxide dismutase 1|superoxide dismutase|