HUGO ID Detailed Result 4312


HUGO ID 4312
Symbol GCLM
Name glutamate-cysteine ligase, modifier subunit
#Occurrence 7
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
17634371GCLMGCLM3.0and 5'-GCTCTTCCATTTCCGAGTCACTG-3' (242 242 bp glutamate-cysteine ligase modifier subunit (GCLM), GCLM 5'-AATCTTGCCTCCTGCTGTGTGATG-3' and 5'-GGCTTCAATGTCAGGGATGCTTTC-3' (153 153 bp glutamate-cysteine ligase catalytic subunit 
17634371GCLMGCLM3.0GSH biosynthesis and both subunits of the enzyme GCLC and GCLM are transcriptionally regulated by Nrf2 a redox-sensitive transcription factor and 
17634371GCLMGCLM3.0expression which correlated with a decreased transcription of GCLC and GCLM 
17634371GCLMGCLM3.024 h and the expression level of Nrf2 GCLC and GCLM mRNA was determined by relative quantitative RT-PCR as described in 
17634371GCLMGCLM3.0including both subunits of glutamate-cysteine ligase (GCL), GCL GCLC and GCLM the rate-limiting enzyme in reduced glutathione (GSH) GSH biosynthesis ( 
17634371GCLGCL0.2Nrf2 regulated genes including both subunits of glutamate-cysteine ligase (GCL), GCL GCLC and GCLM the rate-limiting enzyme in reduced glutathione (GSH)Junguk Hur
17634371glutamate-cysteine ligase modifier subunitglutamate cysteine ligase modifier subunit1.0pcr primers specific to each gene are as follows: nrf2 5' ttcctctgctgccattagtcagtc 3' and 5' gctcttccatttccgagtcactg 3' 242 bp ; glutamate cysteine ligase modifier subunit gclm 5' aatcttgcctcctgctgtgtgatg 3' and 5' ggcttcaatgtcagggatgctttc 3' 153 bp ; glutamate cysteine ligase catalytic subunit gclc 5' atgaaagtggcacaggagcgag 3' and 5' aaacacgccttccttcccattg 3' 186 bp ;