HUGO ID Detailed Result 3796


HUGO ID 3796
Symbol FOS
Name v-fos FBJ murine osteosarcoma viral oncogene homolog
#Occurrence 20
#Paper 6

 


PMID Match String Actual String Score Flanking text Edited by Edit
11679167AP-1AP-11.0Interestingly the yeast AP-1 family (Yap1p) Yap1p of proteins are involved in the sensing 
17191135FOSFos1.8distal enhancer regions of the HO-1 gene such as Fos/Jun Fos Jun activator protein-1 (AP-1)], AP-1 nuclear factor-kB (NFkB) NFkB and 
17191135FOSFos1.8transcription factors such as the AP-1 family members NF-kB Jun Fos p53 CREB PEBP2/CBF, PEBP2 CBF Myb all involved in fundamental 
17496232AP-1AP-11.0IFN-gamma and LPS that activate transcription factors like NF-kappaB or AP-1 ( 59 
17496232AP-1AP-11.0cyclin D 1 by different mechanisms including the enhancement of AP-1 activity 
10643818c fosc fos1.0cyclic gmp dependent kinase also induces expression of c fos possibly via activation of sre creb or fap [ 14 ].  
11679167ap 1ap 11.0interestingly the yeast ap 1 family yap1p of proteins are involved in the sensing of reactive oxygen species in the different yeasts toone et al. 2001 .  
15896810ap 1ap 11.0there is evidence to support that oxidative stress alters the expression of antioxidant enzymes and enhances expression and/or dna binding of numerous transcription factors including ap 1 fos jun myc erg 1 sapk and nfkb [3] .  
17150307ap 1ap 11.0in addition gsh depletion enhanced oxidative stress markers ap 1 transcriptional activation c jun c fos and ho 1 expression in nsc34 cells analyzed by a luciferase reporter western blotting and quantitative pcr assays respectively.  
17150307c fosc fos1.0in addition gsh depletion enhanced oxidative stress markers ap 1 transcriptional activation c jun c fos and ho 1 expression in nsc34 cells analyzed by a luciferase reporter western blotting and quantitative pcr assays respectively.  
17150307ap 1ap 11.0ea treatment enhanced ap 1 transcriptional activation as detected by a luciferase reporter gene assay figure 3a c jun figure 3b and c fos expression data not shown as detected by western analysis.  
17150307c fosc fos1.0ea treatment enhanced ap 1 transcriptional activation as detected by a luciferase reporter gene assay figure 3a c jun figure 3b and c fos expression data not shown as detected by western analysis.  
17150307ap 1ap 11.0in addition gsh depletion increased the expression of the early oxidative stress markers c jun c fos data not shown and ap 1 activation figure 3 and secondary oxidative stress markers such as ho 1 expression figure 4 .  
17150307c fosc fos1.0in addition gsh depletion increased the expression of the early oxidative stress markers c jun c fos data not shown and ap 1 activation figure 3 and secondary oxidative stress markers such as ho 1 expression figure 4 .  
17191135activator protein 1activator protein 11.0consistent with this several transcription factors that recognize specific binding sites within the promoter and distal enhancer regions of the ho 1 gene such as fos/jun [activator protein 1 ap 1 ] nuclear factor kb nfkb and the more recently identified nrf2 proteins [ 24 26 ] fig 1 b contain cysteine residues whose interaction with oxidant or nitrosant species might be crucial for deter 
17191135ap 1ap 11.0consistent with this several transcription factors that recognize specific binding sites within the promoter and distal enhancer regions of the ho 1 gene such as fos/jun [activator protein 1 ap 1 ] nuclear factor kb nfkb and the more recently identified nrf2 proteins [ 24 26 ] fig 1 b contain cysteine residues whose interaction with oxidant or nitrosant species might be crucial for determinin 
17191135ap 1ap 11.0trx gene contains a series of stress responsive elements various transcription factor binding sites such as sp1 gcf and wt zfp conferring constitutive expression inducible expression elements such as ap 1 ap 2 nf kb oct 1 pea 3 myb and the antioxidant responsive element are [ 71 ].  
17191135ap 1ap 11.0in has been reported to cause the translocation of trx from the cytoplasm to the nucleus where it regulates the redox activation and dna binding activity of critical transcription factors such as the ap 1 family members nf kb jun fos p53 creb pebp2/cbf myb all involved in fundamental processes such as gene expression cell growth and apoptosis [ 72 ].  
17496232ap 1ap 11.0and does not depend on ca concentration; nos ii gene expression is modulated by inflammatory mediators like cytokines tnf alpha ifn gamma and lps that activate transcription factors like nf kappab or ap 1 59 .  
17496232ap 1ap 11.0erks stimulate cell proliferation and induction of active cyclin d 1 by different mechanisms including the enhancement of ap 1 activity.