HUGO ID Detailed Result 18985


HUGO ID 18985
Symbol DCXR
Name dicarbonyl/L-xylulose reductase
#Occurrence 7
#Paper 2

 


PMID Match String Actual String Score Flanking text Edited by Edit
16227974carbonyl reductasecarbonyl reductase1.0the levels of carbonylated proteins increase dramatically with age 15 and mutants of d. melanogaster that lack carbonyl reductase activity suffer from neurodegenerative symptoms 16 .  
16406002carbonyl reductasecarbonyl reductase1.0combining findings on neurodegeneration and oxidative stress in drosophila with studies on the metabolic characteristics of the human enzyme carbonyl reductase cr it is clear now that cr has a potential physiological role for neuroprotection in humans.  
16406002carbonyl reductasecarbonyl reductase1.0sniffer is a carbonyl reductase and belongs to the superfamily of short chain dehydrogenases/reductases  
16406002carbonyl reductasecarbonyl reductase1.0it turned out as a surprise that according to its primary structure sniffer shows similarity with human carbonyl reductase cr; secondary alcohol: nadp + oxidoreductase; ec 1.1.1.184 [14] .  
16406002carbonyl reductasecarbonyl reductase1.0sniffer is so far the only known functional carbonyl reductase in drosophila melanogaster which emphasizes the importance of this enzyme as a neuroprotective agent [5] .  
16406002carbonyl reductasecarbonyl reductase1.0carbonyl reductase plays a unique role in the detoxification of reactive aldehydes derived from lipid peroxidation  
16406002carbonyl reductasecarbonyl reductase1.0acid; hne = 4 hydroxynon 2 enal; hno = 1 hydroxynon 2 en 4 one; ona = 4 oxononanal; one = 4 oxonon 2 enal; gsh = reduced glutathione ar = aldose reductase akr1b1 ; aldh = aldehyde dehydrogenase; cr = carbonyl reductase.