HUGO ID Detailed Result 14929


HUGO ID 14929
Symbol SIRT1
Name sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
#Occurrence 10
#Paper 2

 


PMID Match String Actual String Score Flanking text Edited by Edit
16227974SIRT1SIRT10.3The closest mammalian orthologue of SIR-2 is SIRT1 and it is presently not known whether overexpression of SIRT1 
16227974SIRT1SIRT10.3SIRT1 and it is presently not known whether overexpression of SIRT1 will extend mammalian lifespan 
16227974SIRT1SIRT10.3cells from accumulation of oxidatively damaged proteins 50 and mammalian SIRT1 and SIRT3 might modulate mitochondrial activity 51 52 
16227974SIRT1SIRT10.3Recent studies have shown that overexpressing SIRT1 in mice seems to protect neurons from at least some 
16227974SIRT1SIRT10.3alpha-synuclein APP ATM JunD parkin peroxiredoxin I PINK1 Ras seladin-1 SIRT1 SIRT3 SOD1 
17937892SIRT1SIRT11.0[SIRT1/PGC-1: SIRT1 PGC-1 a neuroprotective axis 
17937892SIRT1SIRT11.0it has been recently demonstrated that activation of the SIRT1/PGC-1 SIRT1 PGC-1 pathway in a metabolic context promotes mitochondrial function we 
17937892SIRT1SIRT11.0As evidenced from independent investigations enhanced SIRT1 activity has been demonstrated to protect against axonal degeneration and 
17937892SIRT1SIRT11.0addition several studies suggest that resveratrol a specific activator of SIRT1 could have protective effects in animal models of neurodegenerative diseases 
17937892SIRT1SIRT11.0these results strongly suggest that the modulation of the SIRT1/PGC-1 SIRT1 PGC-1 pathway which has not been well documented in the