SciMiner Result Report Page

Congratulation! Your query with SciMiner has been successfully completed. Your query and search options were

[ HIDE search option summary ]
 Query ID # 16
 User name Junguk Hur
 Email juhur@umich.edu
 Query name ALS INF
 Query string 
 PMID count # 168
 Score threshold 0.1
 Other Remove_phenotype_gene, Use_symbol_length_option, Always_accept_symbol_longer_than: 6

Summary

SciMiner has analyzed (168)  articles.     [Documents Summary]     [PMIDs]
Here is the summary of identified targets. To view the final list of merged targets, click the number in the Unique targets/Merged cell or Full result HTML in the section below. If you are interested in the raw data files, they are available at the bottom of this page.

  Identified Targets
  Before filtering After filtering Unique targets
Symbol-based mining  10058  7513  416
Name-based mining  2990  2715  298
Merged  13048  10228  555 (detail)



Top 10 most frequent targets ... (All 555 genes)

Here are the top 10 most frequently found targets from your query. They are sorted primarily by the number of paper and then by the number of occurrence.

[ HIDE Top 10 most frequent targets ]
Rank HUGO Symbol Target Name #Occur #Paper MiMI
111179SOD1superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))137262
211892TNFtumor necrosis factor (TNF superfamily, member 2)47543
37873NOS2Anitric oxide synthase 2A (inducible, hepatocytes)17234
4620APPamyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)15629
59605PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)144826
66018IL6interleukin 6 (interferon, beta 2)28725
74235GFAPglial fibrillary acidic protein9522
85992IL1Binterleukin 1, beta15318
95438IFNGinterferon, gamma5516
101504CASP3caspase 3, apoptosis-related cysteine peptidase5214

Full result (HTML,   TXT,   EXCEL)

 

 


View the interaction network (MiMI data)

You can create an interaction network of the targets found above. Interaction data is based on the MiMI (Michigan Molecular Interactions) database. The network will be visualized by Cytoscape with the support of MiMI plugin.

    Generate_Network    Download Symbols

 


Top 10 most enriched MeSH terms (sorted by p-value)

Here are the MeSH terms that are highly enriched in your query(corpus) when compared to all other PubMed documents. The comparison was done by Fishers Exact test. The default significance level is 0.05 and any p-value smaller than 0.05 is shown in red. Use the EXCEL file below to sort by enrichment fold (t-ratio / b-ratio).

[ HIDE Top 10 most enriched MeSH terms ]
Corpus size 168 Background(MedLine) 17760657 Switch table detail
Rank MeSH Term t+ t- b+ b- p-value t-ratio b-ratio enrichment
folds
1Amyotrophic Lateral Sclerosis91778337177523202.64e-2540.540.001153.9
2Inflammation6510355717177049404.39e-1160.390.00123.3
3Neurodegenerative Diseases281405168177554896.23e-680.170.00572.8
4Superoxide Dismutase3513326196177344611.12e-630.210.00141.2
5Microglia221465795177548623.80e-500.130.00401.3
6Spinal Cord3113759022177016355.85e-440.180.0055.5
7Neuroprotective Agents2014812617177480404.00e-380.120.00167.6
8Motor Neurons2214629190177314678.56e-350.130.0079.7
9Mice, Transgenic2414445005177156522.55e-340.140.0056.4
10Disease Models, Animal31137130525176301321.65e-330.180.0125.1

Full result (HTML,   TXT,   EXCEL)

 


Result files

Here are the raw result files of SciMiner mining. If you are interested in seeing all the individual identification results, these files are useful to you. These files can also be useful in your generating customary filters. For example, check the Filtered out results, to see any targets you are quite certain that should be included in the result. Put such targets into your INCLUDE filter list and run the same query again.

These files are usually large and we recommend you save these files and load them in a text editor or in EXCEL. Check File Format of these files.
  Before filtering After filtering Filtered out Unique targets
Symbol-based mining 2MB 1MB 857KB 37KB
Name-based mining 890KB 801KB 89KB 30KB
Merged 3MB 2MB 55KB 55KB

 

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