Current Target Information
| HUGO ID | 5992 |
|---|---|
| Symbol | IL1B |
| Name | interleukin 1, beta |
| #Occurrence | 153 |
| #Paper | 18 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 15210305 | Spinal cord molecular profiling provides a better understanding of amyotrophic lateral sclerosis pathogenesis. | 66 | | Brain Res Brain Res Rev |
| 16624536 | Innate immunity in amyotrophic lateral sclerosis. | 54 | | Biochim Biophys Acta |
| 18464925 | Regulation of Glial Cell Functions by PPAR-gamma Natural and Synthetic Agonists. | 35 | | PPAR Res |
| 16510725 | Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis. | 24 | | J Neurosci |
| 17018025 | Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia. | 23 | | J Neurochem |
| 17582695 | Are multiple sclerosis and amyotrophic lateral sclerosis autoimmune disorders of endogenous vasoactive neuropeptides? | 21 | | Med Hypotheses |
| 18040778 | Microglia as a pharmacological target in infectious and inflammatory diseases of the brain. | 20 | | J Neuroimmune Pharmacol |
| 17597167 | Inflammation in the nervous system--physiological and pathophysiological aspects. | 19 | | Physiol Behav |
| 17555556 | Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia. | 18 | | J Neurochem |
| 10525172 | Neurodegenerative disorders: the role of peroxynitrite. | 17 | | Brain Res Brain Res Rev |
| 15453089 | Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases. | 17 | | J Neuropathol Exp Neurol |
| 17008387 | Pyrrolidine dithiocarbamate inhibits induction of immunoproteasome and decreases survival in a rat model of amyotrophic lateral sclerosis. | 16 | | Mol Pharmacol |
| 14511332 | Expression and localization of cyclooxygenase-1 and -2 in human sporadic amyotrophic lateral sclerosis. | 11 | | Eur J Neurosci |
| 12843244 | Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis. | 10 | | J Neurosci |
| 12124437 | Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. | 9 | | J Neurochem |
| 9562310 | Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases. | 6 | | J Neurol Sci |
| 18414597 | Altered Lipid Metabolism in Brain Injury and Disorders. | 5 | | Subcell Biochem |
| 18751914 | Altered lipid metabolism in brain injury and disorders. | 5 | | Subcell Biochem |