Current Target Information
| HUGO ID | 5464 |
|---|---|
| Symbol | IGF1 |
| Name | insulin-like growth factor 1 (somatomedin C) |
| #Occurrence | 198 |
| #Paper | 8 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 11173059 | Pharmacogenomics of neurodegenerative diseases. | 64 | | Eur J Pharmacol |
| 17015226 | ALS: a disease of motor neurons and their nonneuronal neighbors. | 51 | | Neuron |
| 15572176 | A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. | 27 | | Brain Res Brain Res Rev |
| 17018025 | Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia. | 23 | | J Neurochem |
| 17555556 | Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia. | 18 | | J Neurochem |
| 15657392 | Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model. | 15 | | J Cell Biol |
| 16877542 | The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. | 13 | | Proc Natl Acad Sci U S A |
| 12137643 | Recombinant human insulin-like growth factor I (rhIGF-I) for amyotrophic lateral sclerosis/motor neuron disease. | 1 | | Cochrane Database Syst Rev |