Current Target Information
| HUGO ID | 1504 |
|---|---|
| Symbol | CASP3 |
| Name | caspase 3, apoptosis-related cysteine peptidase |
| #Occurrence | 52 |
| #Paper | 14 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 15210305 | Spinal cord molecular profiling provides a better understanding of amyotrophic lateral sclerosis pathogenesis. | 66 | ![]() ![]() ![]() ![]() | Brain Res Brain Res Rev |
| 11173059 | Pharmacogenomics of neurodegenerative diseases. | 64 | ![]() ![]() ![]() ![]() | Eur J Pharmacol |
| 16647138 | Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders. | 59 | ![]() ![]() ![]() ![]() | Brain Res Rev |
| 16624536 | Innate immunity in amyotrophic lateral sclerosis. | 54 | ![]() ![]() ![]() ![]() | Biochim Biophys Acta |
| 17015226 | ALS: a disease of motor neurons and their nonneuronal neighbors. | 51 | ![]() ![]() ![]() ![]() | Neuron |
| 15572176 | A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. | 27 | ![]() ![]() ![]() ![]() | Brain Res Brain Res Rev |
| 15081582 | Neuroinflammation, COX-2, and ALS--a dual role? | 25 | ![]() ![]() ![]() ![]() | Exp Neurol |
| 15571972 | Clinical potential of minocycline for neurodegenerative disorders. | 14 | ![]() ![]() ![]() ![]() | Neurobiol Dis |
| 17997855 | Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury. | 14 | ![]() ![]() ![]() ![]() | BMC Infect Dis |
| 18436268 | Folic acid protects motor neurons against the increased homocysteine, inflammation and apoptosis in SOD1 G93A transgenic mice. | 12 | ![]() ![]() ![]() ![]() | Neuropharmacology |
| 12843244 | Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis. | 10 | ![]() ![]() ![]() ![]() | J Neurosci |
| 12060810 | Minocycline delays disease onset and mortality in a transgenic model of ALS. | 7 | ![]() ![]() ![]() ![]() | Neuroreport |
| 16737688 | Ascending neuropathology in the CNS of a mutant SOD1 mouse model of amyotrophic lateral sclerosis. | 5 | ![]() ![]() ![]() ![]() | Brain Res |
| 17114826 | Aluminum adjuvant linked to Gulf War illness induces motor neuron death in mice. | 1 | ![]() ![]() ![]() ![]() | Neuromolecular Med |