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| 16647138 | EP1 | EP1 | 1.2 | The interaction of PGE 2 with a nuclear EP1 receptor also results in calcium mobilization and gene transcription ( | |  |
| 16647138 | EP1 | EP1 | 1.2 | Collective evidence suggests that cross talk between NMDA and EP1 receptors and generation of AA metabolites may regulate gene expression | |  |
| 16647138 | EP1 | EP1 | 1.2 | PGE 2 mediated through the EP1 receptor has a possible role in the spinal cord ( | |  |
| 16647138 | EP1 | EP1 | 1.2 | EP1 receptors are coupled to calcium ion mobilization and their activation | |  |
| 16647138 | EP1 | EP1 | 1.2 | (1994a) 1994a reported that an EP1 receptor antagonist dose-dependently antagonized PGE 2 -induced allodynia in the | |  |
| 16647138 | EP1 | EP1 | 1.2 | (2004) 2004 demonstrated that a highly selective EP1 receptor antagonist ONO-8711 markedly suppressed PGE 2 -induced Ca 2 | |  |
| 16647138 | EP1 | EP1 | 1.2 | In addition hybridization in situ revealed EP1 receptor signals in the dorsal root ganglion (DRG) DRG neurons | |  |
| 16647138 | EP1 | EP1 | 1.2 | DRG neurons but not in the spinal cord indicating that EP1 receptor mRNA is located at the terminals of DRG afferent | |  |
| 16647138 | EP1 | EP1 | 1.2 | The EP1 antagonist also reduced mechanical allodynia induced by von Frey filaments | |  |
| 16647138 | EP1 | EP1 | 1.2 | EP1 and EP3 agonists had little effect on membrane currents confirming | |  |
| 16647138 | EP1 | EP1 | 1.2 | Mice lacking EP1 EP2 and EP4 receptors responded to PGE 2 injections with | |  |
| 16647138 | EP1 | EP1 | 1.2 | (2001) 2001 proposed a role for the EP1 receptor in pain perception | |  |
| 16647138 | EP1 | EP1 | 1.2 | EP1 _amp_#x2212;/_amp_#x2212; _amp_#x2212 _amp_#x2212 mice were healthy and fertile but with | |  |
| 16647138 | EP1 | EP1 | 1.2 | The observation that both EP1 and IP receptors ( Oida et al. 1995 are expressed | |  |
| 16647138 | EP1 | EP1 | 1.2 | to note that in addition to IP mRNA mRNAs for EP1 EP3 and EP4 were expressed in about 30% 50% and | |  |
| 16647138 | EP1 | EP1 | 1.2 | 30% 50% and 20% of the IP-receptor-positive neurons coexpressing the EP1 EP3 and EP4 receptor respectively ( Oida et al. 1995 | |  |
| 16647138 | EP1 | EP1 | 1.2 | Prostaglandin EP1 receptors may be essential for the neurotoxic effects of COX-2-derived | |  |
| 16647138 | EP1 | EP1 | 1.2 | EP1 receptor activation by PGE 2 disrupts neuronal calcium homeostasis by | |  |
| 16647138 | EP1 | EP1 | 1.2 | Pharmacological inhibition or gene inactivation of EP1 receptors reduces brain injury induced by middle cerebral artery occlusion | |  |
| 17574754 | EP1 | EP1 | 0.3 | 2 EP receptor family where there are four subtypes (EP1, EP1 EP2 EP3 and EP4 and for the PGD 2 DP | |  |
| 17574754 | EP1 | EP1 | 0.3 | A toxic effect of the PGE 2 EP1 receptor has been demonstrated in a model of focal ischemia | |  |
| 17574754 | EP1 | EP1 | 0.3 | has been demonstrated in a model of focal ischemia where EP1 impairs the Na _amp_#x2013 Ca 2 exchange critical in maintaining | |  |