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| 17597167 | IL1RA | IL-1ra | 1.8 | IL-1 receptor (IL-1R)-mediated IL-1R -mediated activity IL-1 receptor antagonist (IL-1ra), IL-1ra that binds to the receptor without the association of the | |  |
| 17597167 | IL1RA | IL-1ra | 1.8 | The existence of two endogenous inhibitors sIL-1RII and IL-1ra underlines the potency of IL-1 both with regard to the | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | The endogenous antagonist of IL-1 receptors IL-1ra is a useful tool to study the role of IL-1R-mediated | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | Thus IL-1ra provides neuroprotection in different models of cerebral ischaemia upon peripheral | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | Furthermore endogenous IL-1ra was shown to be neuroprotective since inhibition of the action | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | shown to be neuroprotective since inhibition of the action of IL-1ra by passive immunoneutralisation enhanced cerebral damage in permanent focal cerebral | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | IL-1ra exists in three isoforms i.e two intracellular forms (icIL-1ra) icIL-1ra | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | Transgenic overexpression of human soluble (hs) hs IL-1ra (Tg Tg hsIL-1ra in the central nervous system (CNS) CNS | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | a post-ischaemic depletion of hsIL-1ra suggesting that the levels of IL-1ra were insufficient to provide neuroprotection under those circumstances particularly in | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | of a cytokine with antiinflammatory properties the endogenous receptor antagonist IL-1ra (see see 41 | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | The expression of IL-1ra mRNA and protein ( 42 see 41 was predominantly seen | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | showed that the proinflammatory cytokine IL-1_amp_#x3b2 preceded both the antiinflammatory IL-1ra and the synthesising enzyme caspase-1 (see see 41 | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | _amp_#x3b1 -melanocyte stimulating hormone (_amp_#x3b1;-MSH) _amp_#x3b1 -MSH 45 whereas both IL-1ra and IL-1RI were found to be expressed in vasopressin neurons | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | and (R)-CPP R -CPP reduced KA-induced expression of IL-1_amp_#x3b2 and IL-1ra 47 indicating that this microglial response to KA is due | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | The ratios between the levels of IL-1_amp_#x3b2 and those of IL-1ra and IL-6 respectively in response to KA changed over time | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | The levels of IL-1ra in the hippocampus were still elevated at 24_amp_#xa0 h ( | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | seems reasonable to hypothesise that the balance between IL-1_amp_#x3b2 and IL-1ra and possibly other cytokines in the hypothalamus has consequences for | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | Together with the finding that i.c.v administration of IL-1ra protects against the pro-epileptogenic effect of IL-1_amp_#x3b2 15 without affecting | | |
| 17597167 | IL1RA | IL-1ra | 1.8 | Homozygotic (Tg Tg IL-1ra +/+ n = 12 mice spent significantly longer time in | | |
| 11173059 | interleukin 1 receptor antagonist | interleukin 1 receptor antagonist | 1.0 | therefore polymorphism analysis of the 1 antichymotrypsin gene especially in conjunction with that of the interleukin 1 gene may provide further indications for the use of anti inflammatory drugs or interleukin 1 receptor antagonist in alzheimer disease table 4 . | | |
| 11173059 | interleukin 1 receptor antagonist | interleukin 1 receptor antagonist | 1.0 | therapeutic trials involving the use of anti inflammatory drugs or interleukin 1 antagonists e.g. interleukin 1 receptor antagonist inhibitors of interleukin 1 converting enzyme are now being planned: results are eagerly awaited as they may lead to substantial changes in treatment protocols for alzheimer disease table 4 . | | |
| 17597167 | icil 1ra | icil 1ra | 1.0 | il 1ra exists in three isoforms i.e. two intracellular forms icil 1ra and one secreted form sil 1ra see [1] . | | |