HUGO ID Detailed Result 5232

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
15341181	HSP	HSP	1.4	genes termed vitagenes and including among others members of the HSP system such as HSP70 and HSP32 to detect and control
15341181	HSP70	HSP70	1.4	including among others members of the HSP system such as HSP70 and HSP32 to detect and control diverse forms of stress
16909005	HSP70	HSP70	1.2	acts potently to increase expression of heat shock proteins including HSP70
16909005	HSP70	HSP70	1.2	HSP70 immunoreactivity was increased in lumbar spinal cord neurons of celastrol-treated
17015226	HSP	HSPs	0.6	examined the protein folding chaperone machinery the heat-shock proteins (HSPs), HSPs in the context of disease
17015226	HSP	HSPs	0.6	Paradoxically some HSPs such as _amp_#x3b1 B-crystallin and Hsp27 are elevated in the
17015226	HSP70	Hsp70	0.6	Hsp70 Hsp40 and Hsp90 are also elevated but only in the
17015226	HSP	HSPs	0.6	Mutant SOD1-mediated depletion of HSPs is a plausible possibility given that Hsp70 and Hsp25 preferentially
17015226	HSP70	Hsp70	0.6	SOD1-mediated depletion of HSPs is a plausible possibility given that Hsp70 and Hsp25 preferentially bind mutant SOD1 ( Okado-Matsumoto and Fridovich
17015226	HSP	HSPs	0.6	Expression of several different HSPs (Hsp70, Hsp70 Hsp40 Hsp27 in cultured cells and primary motor
17015226	HSP70	Hsp70	0.6	Expression of several different HSPs (Hsp70, Hsp70 Hsp40 Hsp27 in cultured cells and primary motor neurons decreases
17015226	HSP70	Hsp70	0.6	Unfortunately applying this strategy in vivo by increased expression of Hsp70 in four different mutant SOD1 mouse lines did not ameliorate
17015226	HSP	HSP	0.6	arimoclomol a drug which induces the phosphorylation-mediated activation of the HSP inducing factor HSF-1 thereby leading to increased levels of Hsp70
17015226	HSP70	Hsp70	0.6	HSP inducing factor HSF-1 thereby leading to increased levels of Hsp70 and Hsp90 in spinal cords ( Kieran et_amp_#xa0 al. 2004
17191135	HSP	Hsp	1.9	Hsp response is also involved in cellular homeostasis during various physiological
17191135	HSP70	Hsp70	3.5	evidence that different NO-releasing agents can markedly increase HO-1 and Hsp70 in a variety of tissues including brain cells 19 20
17191135	HSP70	Hsp70	3.5	both iNOS expression and nitrite levels followed by enhancement of Hsp70 3 20 whereas the modulation of HO-1 mRNA expression by
17191135	HSP70	Hsp70	3.5	by triggering expression of cytoprotective genes such as HO-1 and Hsp70 may lead to adaptation and resistance of brain cells to
17191135	HSP70	Hsp70	3.5	ubiquitin Hsp10 Hsp27 Hsp32 (or or HO-1 Hsp47 Hsp60 Hsc70 Hsp70 (or or Hsp72 Hsp90 and Hsp100/105 Hsp100 105
17191135	HSP72	Hsp72	2.9	Hsp32 (or or HO-1 Hsp47 Hsp60 Hsc70 Hsp70 (or or Hsp72 Hsp90 and Hsp100/105 Hsp100 105
17191135	HSP70	Hsp70	3.5	family are Hsc70 (heat heat shock cognate the constitutive form Hsp70 (the the inducible form also referred to as Hsp72 GRP75
17191135	HSP72	Hsp72	2.9	form Hsp70 (the the inducible form also referred to as Hsp72 GRP75 (a a constitutively expressed glucose-regulated protein found in the
17191135	HSP70	Hsp70	3.5	After a variety of central nervous system (CNS) CNS insults Hsp70 is synthesized at high levels and is present in cytosol
17191135	HSP70	Hsp70	3.5	After heat shock synthesis of Hsp70 may increase to become the most abundant protein in the
17191135	HSP70	Hsp70	3.5	Once synthesized Hsp70 binds to denaturated proteins in an ATP-dependent manner
17191135	HSP70	Hsp70	3.5	cytokine-induced nitrosative stress is associated with an increased synthesis of Hsp70
17191135	HSP70	Hsp70	3.5	Increase in Hsp70 protein expression was also found after treatment of cells with
17191135	HSP70	Hsp70	3.5	(SNP), SNP thus suggesting a role for NO in inducing Hsp70 proteins
17191135	HSP72	Hsp72	2.9	Induction of Hsp72 under stress conditions is often accompanied by the induction of
17191135	HSP72	Hsp72	2.9	acting at three different levels (i) i inducing HO-1 and Hsp72 proteins (ii) ii decreasing the neuronal 3-nitrotyrosine levels and therefore
17191135	HSP70	Hsp70	3.5	During translocation this proteins interact with Hsp70 ATP-dependent binding and the release of Hsp70 provide the major
17191135	HSP70	Hsp70	3.5	proteins interact with Hsp70 ATP-dependent binding and the release of Hsp70 provide the major driving force for complete transport of polypeptides
17191135	HSP70	Hsp70	3.5	Although most imported polypeptides are released from soluble Hsp70 however a subset of aggregation-sensitive polypeptides must be transferred from
17191135	HSP70	Hsp70	3.5	however a subset of aggregation-sensitive polypeptides must be transferred from Hsp70 to Hsp60 for folding 40
17191135	HSP70	Hsp70	3.5	the close functional interaction between this chaperonin system and the Hsp70 system it is likely that up-regulation of Hsp60 may be
17191135	HSP70	Hsp70	3.5	from the cellular machinery and recruitment of chaperone pairs including Hsp70 and Hsp27 endowed with anti-apoptotic properties 85
17191135	HSP70	Hsp70	3.5	Binding of phosphorylated tau to Hsp70 implies that the complex may be a substrate for the
17191135	HSP70	Hsp70	3.5	Together with Hsp70 CHIP can regulate tau ubiquitination and degradation in a cell
17191135	HSP70	Hsp70	3.5	Increased levels of CHIP and Hsp70 has ben detected in AD compared with normal controls 86
17191135	HSP70	Hsp70	3.5	specifically coimmunoprecipitate with AB has identified chaperone proteins such as Hsp70 and alpha B-crystallin-related small Hsp (Hsp16) Hsp16
17191135	HSP	Hsp	1.9	identified chaperone proteins such as Hsp70 and alpha B-crystallin-related small Hsp (Hsp16) Hsp16
17191135	HSP72	Hsp72	2.9	showed an increased expression of inducible nitric oxide synthase HO-1 Hsp72 Hsp60 and TrxR 96
17191135	HSP72	hsp72	2.9	modulates specific genes in the rat CNS such as the hsp72 gene the gene for the isoform of 14-3-3 protein and
17582695	HSP	HSPs	0.9	their association with variable levels of heat shock proteins (HSPs) HSPs 50
17582695	HSP	HSPs	0.9	HSPs may have a role in postulated VN autoimmune disorders 51
15341181	hsp 70	hsp70	1.0	uries brain cells have evolved integrated responses the so called longevity assurance processes composed of several genes termed vitagenes and including among others members of the hsp system such as hsp70 and hsp32 to detect and control diverse forms of stress.
16909005	hsp 70	hsp70	1.0	hsp70 immunoreactivity was increased in lumbar spinal cord neurons of celastrol treated g93a mice.
17015226	hsp 70	hsp70	1.0	hsp70 hsp40 and hsp90 are also elevated but only in the spinal cords of hsod1 g85r mice liu et_amp_#xa0;al. 2005 vleminckx et_amp_#xa0;al. 2002 and wang et_amp_#xa0;al. 2003 .
17015226	hsp 70	hsp70	1.0	mutant sod1 mediated depletion of hsps is a plausible possibility given that hsp70 and hsp25 preferentially bind mutant sod1 okado matsumoto and fridovich 2002 .
17015226	hsp 70	hsp70	1.0	expression of several different hsps hsp70 hsp40 hsp27 in cultured cells and primary motor neurons decreases aggregate content and apoptosis and improves axonal outgrowth bruening et_amp_#xa0;al. 1999 patel et_amp_#xa0;al. 2005 and takeuchi e
17015226	hsp 70	hsp70	1.0	unfortunately applying this strategy in vivo by increased expression of hsp70 in four different mutant sod1 mouse lines did not ameliorate disease or pathology liu et_amp_#xa0;al. 2005 .
17015226	hsp 70	hsp70	1.0	a small cohort of hsod1 g93a mice after treatment with arimoclomol a drug which induces the phosphorylation mediated activation of the hsp inducing factor hsf 1 thereby leading to increased levels of hsp70 and hsp90 in spinal cords kieran et_amp_#xa0;al. 2004 .
17191135	hsp 70	hsp70	1.0	the conception that no and rns can be directly involved in the modulation of ho 1 expression in eukaryotes is based on the evidence that different no releasing agents can markedly increase ho 1 and hsp70 in a variety of tissues including brain cells [ 19 20 ].
17191135	hsp 70	hsp70	1.0	in rat glial cells treatment with lipopolysaccaride lps and interferon g ifn g promotes a rapid increase in both inos expression and nitrite levels followed by enhancement of hsp70 [ 3 20 ] whereas the modulation of ho 1 mrna expression by inos derived no following stimulation with lps has also been reported in different brain regions particularly in the hippocampus and substan
17191135	hsp 70	hsp70	1.0	taken together these findings point to a possible role of the no as a signaling molecule which by triggering expression of cytoprotective genes such as ho 1 and hsp70 may lead to adaptation and resistance of brain cells to subsequent more severe nitrosative and oxidative stress [ 21 23 ].
17191135	hsp 70	hsp70	1.0	some of the known hsps include ubiquitin hsp10 hsp27 hsp32 or ho 1 hsp47 hsp60 hsc70 hsp70 or hsp72 hsp90 and hsp100/105.
17191135	hsp 70	hsp70	1.0	included in this family are hsc70 heat shock cognate the constitutive form hsp70 the inducible form also referred to as hsp72 grp75 a constitutively expressed glucose regulated protein found in the endoplasmic reticulum .
17191135	hsp 70	hsp70	1.0	after a variety of central nervous system cns insults hsp70 is synthesized at high levels and is present in cytosol nucleus and endoplasmic reticulum [ 24 32 ].
17191135	hsp 70	hsp70	1.0	after heat shock synthesis of hsp70 may increase to become the most abundant protein in the cell.
17191135	hsp 70	hsp70	1.0	once synthesized hsp70 binds to denaturated proteins in an atp dependent manner.
17191135	hsp 70	hsp70	1.0	increase in hsp70 protein expression was also found after treatment of cells with the no generating compound sodium nitroprusside snp thus suggesting a role for no in inducing hsp70 proteins.
17191135	hsp 70	hsp70	1.0	during translocation this proteins interact with hsp70 atp dependent binding and the release of hsp70 provide the major driving force for complete transport of polypeptides into the matrix.
17191135	hsp 70	hsp70	1.0	although most imported polypeptides are released from soluble hsp70 however a subset of aggregation sensitive polypeptides must be transferred from hsp70 to hsp60 for folding [ 40 ].
17191135	hsp 70	hsp70	1.0	owing to the close functional interaction between this chaperonin system and the hsp70 system it is likely that up regulation of hsp60 may be a fundamental site targeted by lac action with consequent restoration of complex iv function under conditions of nitrosative stress dependent pe
17191135	hsp 70	hsp70	1.0	onal changes of the protein and ubiquitination clearing misfolded proteins to the proteasome and segregation of tau aggregates from the cellular machinery and recruitment of chaperone pairs including hsp70 and hsp27 endowed with anti apoptotic properties [ 85 ].
17191135	hsp 70	hsp70	1.0	binding of phosphorylated tau to hsp70 implies that the complex may be a substrate for the e3 ligase carboxyl terminus of heat shock cognate hsc 70 interacting protein chip [ 86 88 ].
17191135	hsp 70	hsp70	1.0	together with hsp70 chip can regulate tau ubiquitination and degradation in a cell culture system [ 87 ].
17191135	hsp 70	hsp70	1.0	increased levels of chip and hsp70 has ben detected in ad compared with normal controls [ 86 ].
17191135	hsp 70	hsp70	1.0	mass spectrometry analysis of proteins that specifically coimmunoprecipitate with ab has identified chaperone proteins such as hsp70 and alpha b crystallin related small hsp hsp16 .