HUGO ID Detailed Result 391

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
16104843	AKT	Akt	0.3	is reported to involve the PI3K (phosphoinositide phosphoinositide 3-kinase)/Akt 3-kinase Akt pathway 82 83 ( Figure 2
16104843	AKT	Akt	0.3	has been shown to lead to a PI3K-dependent activation of Akt and PKC (protein protein kinase C -dependent activation of p42/p44
16104843	AKT	Akt	0.3	the activation of eNOS is regulated by the PI3K/Akt PI3K Akt pathway 123 124
16104843	RAC	Rac	1.1	The small GTP-binding protein Rac which is also activated by PI3K has been implicated in
16624536	AKT	Akt	0.6	been observed and attributed to activation of the protein kinase Akt and the nuclear translocation of NF-_amp_#x3ba B 72 and 75
16647138	AKT	Akt	0.3	both endothelial nitric oxide synthase (eNOS) eNOS and PI3-kinase/Akt PI3-kinase Akt pathways
16647138	AKT	Akt	0.3	Not only eNOS inhibitors but also PI3-kinase/Akt PI3-kinase Akt signaling pathway inhibitors can prevent this upregulation by EPOX
16647138	AKT	Akt	0.3	This indicates that both eNOS and PI3-kinase/Akt PI3-kinase Akt pathways may mediate the angiogenic effects of EETs ( Kawasaki
16877542	AKT	Akt	0.3	indicate that such an oxidative modification hinders the IGF1/Akt IGF1 Akt survival pathway in motor neurons
16877542	AKT	Akt	0.2	Keywords Akt ALS microglia oxidation non-cell autonomous
16877542	AKT	Akt	0.0	Phosphorylation of Akt and cell viability in response to IGF1 recombinant and to
16877542	AKT	Akt	0.3	NADPH Oxidase Impairs the Insulin-Like Growth Factor 1 (IGF1)/Akt IGF1 Akt Pathway in Transgenic SOD1 G93A Mice
16877542	AKT	Akt	0.0	findings oxidation indices in the intracellular serine/threonine serine threonine kinase Akt which transduces IGF1 receptor signaling ( 15 did not differ
16877542	AKT	Akt	0.0	There were also smaller phospho-Akt total Akt ratios ( Fig 4 F and G as well as
16877542	AKT	Akt	0.0	fewer cells that were immunoreactive for a downstream target of Akt phospho-BAD ( Fig 4 H _amp_#x02013 J and smaller phospho-BAD
16877542	AKT	Akt	0.3	Microglial-Derived ROS Recapitulate the IGF1/Akt IGF1 Akt Pathway Defect in Vitro
16877542	AKT	Akt	0.0	H 2 O 2 IGF1 pathway responsiveness was monitored by Akt phosphorylation
16877542	AKT	Akt	0.0	Exposure to IGF1 caused a dose-dependent phosphorylation of Akt in SH-SY5Y cells ( Fig 5 A and B and
16877542	AKT	Akt	0.0	Conversely IGF1 barely increased Akt phosphorylation in the neuroblastoma cell lines that were exposed to
16877542	AKT	Akt	0.2	H 2 O 2 ( Fig 5 E attenuated IGF1-mediated Akt phosphorylation in the neuroblastoma cell line ( Fig 5 C
16877542	AKT	Akt	0.0	Upon longer exposure to LPS-activated microglial-conditioned medium the Akt phosphorylation response to the IGF1 recombinant remained depressed and at
16877542	AKT	Akt	0.2	However both the alteration of IGF1-mediated Akt phosphorylation and the loss of cell viability mediated by LPS-activated
16877542	AKT	Akt	0.0	elicited by ligation of the IGF1 receptor including autophosphorylation and Akt phosphorylation were indeed abated by ROS in a microglial NADPH
16877542	AKT	Akt	0.3	Modulation of the IGF1/Akt IGF1 Akt pathway by NADPH oxidase-derived ROS
16877542	AKT	Akt	0.2	Glucose oxidase- and microglial-derived ROS impair the IGF1 Akt pathway in vitro
16877542	AKT	Akt	0.0	( A Phospho-Akt (upper upper blot and total Akt (lower lower blot immunoblots of IGF1-treated SH-SY5Y cells exposed or
17574754	AKT	AKT	0.3	intact cAMP signaling whereas EP3 neuroprotection is associated with increased AKT phosphorylation 3 and 16
17574754	AKT	AKT	0.3	associated with increased levels of the pro-survival phosphorylated form of AKT
17997855	RAC	Rac	0.1	At sublytic concentrations pneumolysin rapidly activates Rho and Rac GTPases and leads to the formation of actin stress fibers
18422522	AKT	Akt	0.0	of sphingosine-1-phosphate stimulation of its membrane receptors and activation of Akt as determined using small interference RNA and dominant negative constructs
16624536	protein kinase b	protein kinase b	1.0	through activation of the phosphatidylinositol 3 kinase/protein kinase b pathway fractalkine will inhibit fas ligand induced microglial apoptosis through down regulation of the pro apoptotic function of bad and up regulation of the anti apoptotic activity of bcl xl [71] t
17350694	protein kinase b	protein kinase b	1.0	mainly owing to the phenol group of various resorcinol type cannabinoids; iv suppression of the production of tumor necrosis factor _amp_#x3b1;; v activation of the phosphatidylinositol 3 kinase and protein kinase b pathway; vi induction of phosphorylation of extracellular regulated kinases; and vii induction of the expression of transcription factors and neurotrophins.