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| 16380619 | AP-1 | AP-1 | 1.0 | TNF-alpha and IL-6 mediated by others transcriptional factors nuclear factor-kappaB AP-1 and SP-1 | |  |
| 16753239 | AP-1 | AP-1 | 1.0 | For example these agonists inhibit transcription factors including NF-_amp_#x3ba B AP-1 and STAT-1 from activating gene expression in this manner | |  |
| 16753239 | AP-1 | AP-1 | 1.0 | studies indicated that gemfibrozil suppressed cytokine induction of NF-_amp_#x3ba B AP-1 and C/EBP-_amp_#x3b2;-dependent C EBP-_amp_#x3b2 -dependent luciferase activity following transfection into | |  |
| 16766086 | AP-1 | AP-1 | 1.3 | the transcriptional level through antagonizing the actions of NF_amp_#x3ba B AP-1 and STAT1 transcription factors ( Daynes and Jones 2002 | |  |
| 17191135 | FOS | Fos | 1.8 | distal enhancer regions of the HO-1 gene such as Fos/Jun Fos Jun activator protein-1 (AP-1)], AP-1 nuclear factor-kB (NFkB) NFkB and | |  |
| 17191135 | FOS | Fos | 1.8 | transcription factors such as the AP-1 family members NF-kB Jun Fos p53 CREB PEBP2/CBF, PEBP2 CBF Myb all involved in fundamental | |  |
| 17569578 | AP-1 | AP-1 | 1.3 | transcription factor NF_amp_#x3ba B (and and to a lesser extent AP-1 and STATs 46 | |  |
| 18464922 | AP-1 | AP-1 | 1.0 | of nuclear factor kappa B NF-_amp_#x003ba B activator protein-1 (AP-1), AP-1 in addition to signal transducers and activators of transcription (STAT) | |  |
| 18464925 | AP-1 | AP-1 | 2.8 | STAT-1 expression and enhanced expression and binding activity of the AP-1 proteins J-Jun and c-Fos 60 | |  |
| 16104843 | ap 1 | ap 1 | 1.0 | very recently gerald et al. [ 29 ] have demonstrated that jund a member of the ap 1 family of transcription factors is involved in the regulation of prolyl hydroxylase activity. | |  |
| 16380619 | ap 1 | ap 1 | 1.0 | on the other hand hypoxia stimulates the proinflammatory cytokines such as tnf alpha and il 6 mediated by others transcriptional factors: nuclear factor kappab ap 1 and sp 1. | |  |
| 16753239 | ap 1 | ap 1 | 1.0 | for example these agonists inhibit transcription factors including nf _amp_#x3ba;b ap 1 and stat 1 from activating gene expression in this manner. | |  |
| 16753239 | ap 1 | ap 1 | 1.0 | furthermore these studies indicated that gemfibrozil suppressed cytokine induction of nf _amp_#x3ba;b ap 1 and c/ebp _amp_#x3b2; dependent luciferase activity following transfection into glial cells. | |  |
| 16766086 | ap 1 | ap 1 | 1.0 | ppar_amp_#x3b3; suppress proinflammatory gene expression at the transcriptional level through antagonizing the actions of nf_amp_#x3ba;b ap 1 and stat1 transcription factors daynes and jones 2002 . | |  |
| 17191135 | activator protein 1 | activator protein 1 | 1.0 | consistent with this several transcription factors that recognize specific binding sites within the promoter and distal enhancer regions of the ho 1 gene such as fos/jun [activator protein 1 ap 1 ] nuclear factor kb nfkb and the more recently identified nrf2 proteins [ 24 26 ] fig 1 b contain cysteine residues whose interaction with oxidant or nitrosant species might be crucial for deter | |  |
| 17191135 | ap 1 | ap 1 | 1.0 | consistent with this several transcription factors that recognize specific binding sites within the promoter and distal enhancer regions of the ho 1 gene such as fos/jun [activator protein 1 ap 1 ] nuclear factor kb nfkb and the more recently identified nrf2 proteins [ 24 26 ] fig 1 b contain cysteine residues whose interaction with oxidant or nitrosant species might be crucial for determinin | |  |
| 17191135 | ap 1 | ap 1 | 1.0 | trx gene contains a series of stress responsive elements various transcription factor binding sites such as sp1 gcf and wt zfp conferring constitutive expression inducible expression elements such as ap 1 ap 2 nf kb oct 1 pea 3 myb and the antioxidant responsive element are [ 71 ]. | |  |
| 17191135 | ap 1 | ap 1 | 1.0 | in has been reported to cause the translocation of trx from the cytoplasm to the nucleus where it regulates the redox activation and dna binding activity of critical transcription factors such as the ap 1 family members nf kb jun fos p53 creb pebp2/cbf myb all involved in fundamental processes such as gene expression cell growth and apoptosis [ 72 ]. | |  |
| 17569578 | ap 1 | ap 1 | 1.0 | s are a result of the ability of ppar_amp_#x3b3; to suppress the promoters of proinflammatory genes through antagonism of the actions of the transcription factor nf_amp_#x3ba;b and to a lesser extent ap 1 and stats [46] . | |  |
| 18464922 | activator protein 1 | activator protein 1 | 1.0 | several anti inflammatory mechanisms have been suggested including inhibition of nuclear factor kappa b nf _amp_#x003ba; b activator protein 1 ap 1 in addition to signal transducers and activators of transcription stat transcription factors by ppar _amp_#x003b3; [ 31 ]. | |  |
| 18464922 | ap 1 | ap 1 | 1.0 | several anti inflammatory mechanisms have been suggested including inhibition of nuclear factor kappa b nf _amp_#x003ba; b activator protein 1 ap 1 in addition to signal transducers and activators of transcription stat transcription factors by ppar _amp_#x003b3; [ 31 ]. | |  |
| 18464925 | activator protein 1 | activator protein 1 | 1.0 | 15d pj 2 = 15 deoxy _amp_#x00394; 12 14 prostaglandin j 2 ad= alzheimer disease als= amyotrophic lateral sclerosis ap 1= activator protein 1 cns= central nervous system cox= cyclooxygenase dbd= dna binding domain eae= experimental autoimmune encephalomyelitis hode= hydroxy octadecadienoic acids ifn= interferon il= interleukin inos= induci | |  |
| 18464925 | ap 1 | ap 1 | 1.0 | 15d pj 2 = 15 deoxy _amp_#x00394; 12 14 prostaglandin j 2 ad= alzheimer disease als= amyotrophic lateral sclerosis ap 1= activator protein 1 cns= central nervous system cox= cyclooxygenase dbd= dna binding domain eae= experimental autoimmune encephalomyelitis hode= hydroxy octadecadienoic acids ifn= interferon il= int | |  |
| 18464925 | ap 1 | ap 1 | 1.0 | in human microglial cells 15d pgj 2 did not affect nf _amp_#x003ba; b binding activity although it decreased stat 1 expression and enhanced expression and binding activity of the ap 1 proteins j jun and c fos [ 60 ]. | |  |
| 18464925 | c fos | c fos | 1.0 | human microglial cells 15d pgj 2 did not affect nf _amp_#x003ba; b binding activity although it decreased stat 1 expression and enhanced expression and binding activity of the ap 1 proteins j jun and c fos [ 60 ]. | |  |