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| 16647138 | COX | COX-1-deficient | 0.3 | COX-1-deficient mice have very low (1% 1% of normal PG levels | |  |
| 16647138 | COX | COX-1-deficient | 0.3 | and increased susceptibility to ischemic brain injury in COX-2- and COX-1-deficient mice respectively | | |
| 16647138 | COX | COX-1-deficient | 0.3 | reperfusion injury was increased ( Iadecola et al. 2001b in COX-1-deficient mice | | |
| 16647138 | COX | COX-2-derived | 0.3 | has been attributed to blockade of the vasoprotective effects of COX-2-derived PGI 2 ( FitzGerald 2003 | | |
| 16647138 | COX | COX-2-derived | 0.3 | EP1 receptors may be essential for the neurotoxic effects of COX-2-derived PGE 2 | | |
| 18464925 | COX | COXs | 0.0 | exceeding those required for in vivo inhibition of cyclooxygenases (COXs), COXs the main target of these drugs | | |