HUGO ID Detailed Result 11777


HUGO ID 11777
Symbol TGM1
Name transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
#Occurrence 8
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
15507874TGASETGase1.3Transglutaminase (TGase)2 TGase 2 is an enzyme that is widely used in many 
15507874TGASETGase1.3Many reports showed that TGase 2 is aberrantly activated in tissues and cells and contributes 
15507874TGASETGase1.3In most cases TGase 2 appears to be a factor in the formation of 
15507874TGASETGase1.3such as celiac disease arthritis lupus and amyotrophic lateral sclerosis TGase 2 is involved in the generation of autoantibodies 
15507874TGASETGase1.3the possibility that inappropriate expression and/or and or presentation of TGase 2 to T cells might contribute to these diseases in 
15507874TGASETGase1.3We and others have found that TGase 2 expression is also increased in the inflammation process 
15507874TGASETgase1.3Furthermore we also demonstrated a reversal of inflammation by Tgase inhibition 
15507874TGASETGase1.3This review will examine a possibility of TGase inhibitors as therapeutic agents in a variety of inflammatory diseases