1 | Level2 | GO:0005488 | binding | 919 | 107 | 12737 | 12517 | 3.18e-153 | 0.90 | 0.50 | 1.8 |
2 | Level3 | GO:0005515 | protein binding | 717 | 309 | 7817 | 17437 | 3.81e-138 | 0.70 | 0.31 | 2.3 |
3 | Level2 | GO:0003824 | catalytic activity | 581 | 445 | 5927 | 19327 | 2.47e-109 | 0.57 | 0.23 | 2.4 |
4 | Level3 | GO:0016491 | oxidoreductase activity | 164 | 862 | 950 | 24304 | 8.34e-51 | 0.16 | 0.04 | 4.2 |
5 | Level4 | GO:0005102 | receptor binding | 161 | 865 | 968 | 24286 | 5.69e-48 | 0.16 | 0.04 | 4.1 |
6 | Level5 | GO:0030554 | adenyl nucleotide binding | 197 | 829 | 1799 | 23455 | 7.88e-35 | 0.19 | 0.07 | 2.7 |
7 | Level3 | GO:0016740 | transferase activity | 210 | 816 | 2049 | 23205 | 1.71e-33 | 0.20 | 0.08 | 2.5 |
8 | Level4 | GO:0046872 | metal ion binding | 346 | 680 | 4562 | 20692 | 1.13e-31 | 0.34 | 0.18 | 1.9 |
9 | Level4 | GO:0017076 | purine nucleotide binding | 213 | 813 | 2163 | 23091 | 1.25e-31 | 0.21 | 0.09 | 2.4 |
10 | Level4 | GO:0009055 | electron carrier activity | 77 | 949 | 330 | 24924 | 3.30e-31 | 0.08 | 0.01 | 5.7 |
11 | Level3 | GO:0043167 | ion binding | 349 | 677 | 4652 | 20602 | 4.98e-31 | 0.34 | 0.18 | 1.8 |
12 | Level2 | GO:0060089 | molecular transducer activity | 257 | 769 | 2965 | 22289 | 1.87e-30 | 0.25 | 0.12 | 2.1 |
13 | Level3 | GO:0004871 | signal transducer activity | 257 | 769 | 2965 | 22289 | 1.87e-30 | 0.25 | 0.12 | 2.1 |
14 | Level3 | GO:0000166 | nucleotide binding | 228 | 798 | 2516 | 22738 | 3.50e-29 | 0.22 | 0.10 | 2.2 |
15 | Level4 | GO:0046983 | protein dimerization activity | 82 | 944 | 422 | 24832 | 2.09e-28 | 0.08 | 0.02 | 4.8 |
16 | Level5 | GO:0016301 | kinase activity | 129 | 897 | 1020 | 24234 | 1.01e-27 | 0.13 | 0.04 | 3.1 |
17 | Level4 | GO:0016772 | transferase activity\, transferring phosphorus\-containing groups | 139 | 887 | 1169 | 24085 | 1.86e-27 | 0.14 | 0.05 | 2.9 |
18 | Level5 | GO:0016773 | phosphotransferase activity\, alcohol group as acceptor | 115 | 911 | 880 | 24374 | 8.29e-26 | 0.11 | 0.03 | 3.2 |
19 | Level4 | GO:0042802 | identical protein binding | 82 | 944 | 471 | 24783 | 1.33e-25 | 0.08 | 0.02 | 4.3 |
20 | Level4 | GO:0032553 | ribonucleotide binding | 192 | 834 | 2072 | 23182 | 2.12e-25 | 0.19 | 0.08 | 2.3 |
21 | Level5 | GO:0032555 | purine ribonucleotide binding | 192 | 834 | 2072 | 23182 | 2.12e-25 | 0.19 | 0.08 | 2.3 |
22 | Level3 | GO:0048037 | cofactor binding | 63 | 963 | 276 | 24978 | 2.86e-25 | 0.06 | 0.01 | 5.6 |
23 | Level4 | GO:0043169 | cation binding | 308 | 718 | 4228 | 21026 | 1.19e-24 | 0.30 | 0.17 | 1.8 |
24 | Level3 | GO:0016787 | hydrolase activity | 218 | 808 | 2642 | 22612 | 7.71e-23 | 0.21 | 0.10 | 2.0 |
25 | Level4 | GO:0050662 | coenzyme binding | 46 | 980 | 196 | 25058 | 3.43e-19 | 0.04 | 0.01 | 5.8 |
26 | Level5 | GO:0008083 | growth factor activity | 49 | 977 | 225 | 25029 | 3.44e-19 | 0.05 | 0.01 | 5.4 |
27 | Level3 | GO:0046906 | tetrapyrrole binding | 44 | 982 | 178 | 25076 | 3.80e-19 | 0.04 | 0.01 | 6.1 |
28 | Level4 | GO:0020037 | heme binding | 44 | 982 | 178 | 25076 | 3.80e-19 | 0.04 | 0.01 | 6.1 |
29 | Level4 | GO:0005057 | receptor signaling protein activity | 44 | 982 | 182 | 25072 | 7.83e-19 | 0.04 | 0.01 | 6.0 |
30 | Level5 | GO:0046914 | transition metal ion binding | 224 | 802 | 2996 | 22258 | 2.02e-18 | 0.22 | 0.12 | 1.8 |
31 | Level2 | GO:0016209 | antioxidant activity | 26 | 1000 | 63 | 25191 | 3.46e-16 | 0.03 | 0.00 | 10.2 |
32 | Level5 | GO:0004175 | endopeptidase activity | 66 | 960 | 494 | 24760 | 1.33e-15 | 0.06 | 0.02 | 3.3 |
33 | Level5 | GO:0005125 | cytokine activity | 50 | 976 | 300 | 24954 | 2.17e-15 | 0.05 | 0.01 | 4.1 |
34 | Level5 | GO:0042803 | protein homodimerization activity | 42 | 984 | 215 | 25039 | 3.37e-15 | 0.04 | 0.01 | 4.8 |
35 | Level4 | GO:0019899 | enzyme binding | 52 | 974 | 336 | 24918 | 8.56e-15 | 0.05 | 0.01 | 3.8 |
36 | Level5 | GO:0000287 | magnesium ion binding | 62 | 964 | 471 | 24783 | 1.81e-14 | 0.06 | 0.02 | 3.2 |
37 | Level5 | GO:0005509 | calcium ion binding | 109 | 917 | 1179 | 24075 | 2.47e-14 | 0.11 | 0.05 | 2.3 |
38 | Level5 | GO:0046982 | protein heterodimerization activity | 33 | 993 | 142 | 25112 | 4.76e-14 | 0.03 | 0.01 | 5.7 |
39 | Level4 | GO:0008134 | transcription factor binding | 64 | 962 | 511 | 24743 | 5.36e-14 | 0.06 | 0.02 | 3.1 |
40 | Level5 | GO:0005179 | hormone activity | 37 | 989 | 183 | 25071 | 5.97e-14 | 0.04 | 0.01 | 5.0 |
41 | Level4 | GO:0004872 | receptor activity | 177 | 849 | 2469 | 22785 | 5.57e-13 | 0.17 | 0.10 | 1.8 |
42 | Level4 | GO:0008233 | peptidase activity | 77 | 949 | 741 | 24513 | 1.13e-12 | 0.08 | 0.03 | 2.6 |
43 | Level3 | GO:0001871 | pattern binding | 30 | 996 | 140 | 25114 | 4.00e-12 | 0.03 | 0.01 | 5.3 |
44 | Level3 | GO:0016563 | transcription activator activity | 50 | 976 | 382 | 24872 | 7.77e-12 | 0.05 | 0.02 | 3.2 |
45 | Level3 | GO:0004601 | peroxidase activity | 19 | 1007 | 49 | 25205 | 8.05e-12 | 0.02 | 0.00 | 9.5 |
46 | Level4 | GO:0016684 | oxidoreductase activity\, acting on peroxide as acceptor | 19 | 1007 | 49 | 25205 | 8.05e-12 | 0.02 | 0.00 | 9.5 |
47 | Level5 | GO:0050660 | FAD binding | 24 | 1002 | 89 | 25165 | 9.57e-12 | 0.02 | 0.00 | 6.6 |
48 | Level2 | GO:0030234 | enzyme regulator activity | 87 | 939 | 954 | 24300 | 2.49e-11 | 0.08 | 0.04 | 2.2 |
49 | Level3 | GO:0016829 | lyase activity | 34 | 992 | 196 | 25058 | 2.57e-11 | 0.03 | 0.01 | 4.3 |
50 | Level4 | GO:0030247 | polysaccharide binding | 27 | 999 | 125 | 25129 | 4.03e-11 | 0.03 | 0.00 | 5.3 |
51 | Level5 | GO:0042578 | phosphoric ester hydrolase activity | 49 | 977 | 389 | 24865 | 4.26e-11 | 0.05 | 0.02 | 3.1 |
52 | Level4 | GO:0016788 | hydrolase activity\, acting on ester bonds | 75 | 951 | 770 | 24484 | 4.43e-11 | 0.07 | 0.03 | 2.4 |
53 | Level5 | GO:0005539 | glycosaminoglycan binding | 26 | 1000 | 118 | 25136 | 6.33e-11 | 0.03 | 0.00 | 5.4 |
54 | Level2 | GO:0030528 | transcription regulator activity | 126 | 900 | 1681 | 23573 | 1.95e-10 | 0.12 | 0.07 | 1.8 |
55 | Level4 | GO:0016705 | oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen | 28 | 998 | 149 | 25105 | 2.95e-10 | 0.03 | 0.01 | 4.6 |
56 | Level2 | GO:0005215 | transporter activity | 127 | 899 | 1746 | 23508 | 9.04e-10 | 0.12 | 0.07 | 1.8 |
57 | Level3 | GO:0008289 | lipid binding | 50 | 976 | 445 | 24809 | 9.81e-10 | 0.05 | 0.02 | 2.8 |
58 | Level4 | GO:0032403 | protein complex binding | 25 | 1001 | 128 | 25126 | 1.31e-09 | 0.02 | 0.01 | 4.8 |
59 | Level3 | GO:0004857 | enzyme inhibitor activity | 41 | 985 | 326 | 24928 | 1.73e-09 | 0.04 | 0.01 | 3.1 |
60 | Level4 | GO:0019904 | protein domain specific binding | 26 | 1000 | 143 | 25111 | 2.33e-09 | 0.03 | 0.01 | 4.5 |
61 | Level3 | GO:0022892 | substrate\-specific transporter activity | 108 | 918 | 1433 | 23821 | 3.71e-09 | 0.11 | 0.06 | 1.9 |
62 | Level4 | GO:0016614 | oxidoreductase activity\, acting on CH\-OH group of donors | 27 | 999 | 160 | 25094 | 4.78e-09 | 0.03 | 0.01 | 4.2 |
63 | Level3 | GO:0022857 | transmembrane transporter activity | 99 | 927 | 1283 | 23971 | 5.05e-09 | 0.10 | 0.05 | 1.9 |
64 | Level5 | GO:0003700 | transcription factor activity | 90 | 936 | 1123 | 24131 | 5.06e-09 | 0.09 | 0.04 | 2.0 |
65 | Level5 | GO:0009053 | electron donor activity | 11 | 1015 | 18 | 25236 | 5.52e-09 | 0.01 | 0.00 | 15.0 |
66 | Level3 | GO:0030246 | carbohydrate binding | 42 | 984 | 363 | 24891 | 1.01e-08 | 0.04 | 0.01 | 2.8 |
67 | Level3 | GO:0016853 | isomerase activity | 31 | 995 | 217 | 25037 | 1.22e-08 | 0.03 | 0.01 | 3.5 |
68 | Level4 | GO:0004497 | monooxygenase activity | 25 | 1001 | 147 | 25107 | 1.54e-08 | 0.02 | 0.01 | 4.2 |
69 | Level5 | GO:0019900 | kinase binding | 22 | 1004 | 117 | 25137 | 2.31e-08 | 0.02 | 0.00 | 4.6 |
70 | Level5 | GO:0003712 | transcription cofactor activity | 41 | 985 | 362 | 24892 | 2.59e-08 | 0.04 | 0.01 | 2.8 |
71 | Level5 | GO:0016616 | oxidoreductase activity\, acting on the CH\-OH group of donors\, NAD or NADP as acceptor | 24 | 1002 | 143 | 25111 | 3.71e-08 | 0.02 | 0.01 | 4.1 |
72 | Level3 | GO:0019842 | vitamin binding | 25 | 1001 | 155 | 25099 | 3.88e-08 | 0.02 | 0.01 | 4.0 |
73 | Level3 | GO:0019207 | kinase regulator activity | 22 | 1004 | 124 | 25130 | 5.75e-08 | 0.02 | 0.00 | 4.4 |
74 | Level3 | GO:0016564 | transcription repressor activity | 32 | 994 | 271 | 24983 | 3.76e-07 | 0.03 | 0.01 | 2.9 |
75 | Level4 | GO:0016835 | carbon\-oxygen lyase activity | 16 | 1010 | 79 | 25175 | 7.90e-07 | 0.02 | 0.00 | 5.0 |
76 | Level5 | GO:0004888 | transmembrane receptor activity | 118 | 908 | 1808 | 23446 | 9.05e-07 | 0.12 | 0.07 | 1.6 |
77 | Level5 | GO:0015399 | primary active transmembrane transporter activity | 25 | 1001 | 189 | 25065 | 1.11e-06 | 0.02 | 0.01 | 3.3 |
78 | Level3 | GO:0019825 | oxygen binding | 13 | 1013 | 53 | 25201 | 1.36e-06 | 0.01 | 0.00 | 6.0 |
79 | Level5 | GO:0042169 | SH2 domain binding | 9 | 1017 | 21 | 25233 | 1.39e-06 | 0.01 | 0.00 | 10.5 |
80 | Level4 | GO:0016627 | oxidoreductase activity\, acting on the CH\-CH group of donors | 17 | 1009 | 95 | 25159 | 1.63e-06 | 0.02 | 0.00 | 4.4 |
81 | Level5 | GO:0050661 | NADP binding | 10 | 1016 | 30 | 25224 | 2.30e-06 | 0.01 | 0.00 | 8.2 |
82 | Level4 | GO:0030170 | pyridoxal phosphate binding | 14 | 1012 | 66 | 25188 | 2.39e-06 | 0.01 | 0.00 | 5.2 |
83 | Level4 | GO:0019955 | cytokine binding | 22 | 1004 | 159 | 25095 | 2.49e-06 | 0.02 | 0.01 | 3.4 |
84 | Level4 | GO:0008022 | protein C\-terminus binding | 17 | 1009 | 100 | 25154 | 3.02e-06 | 0.02 | 0.00 | 4.2 |
85 | Level5 | GO:0043565 | sequence\-specific DNA binding | 53 | 973 | 637 | 24617 | 3.25e-06 | 0.05 | 0.03 | 2.0 |
86 | Level4 | GO:0022804 | active transmembrane transporter activity | 48 | 978 | 559 | 24695 | 3.83e-06 | 0.05 | 0.02 | 2.1 |
87 | Level4 | GO:0022891 | substrate\-specific transmembrane transporter activity | 83 | 943 | 1190 | 24064 | 5.08e-06 | 0.08 | 0.05 | 1.7 |
88 | Level4 | GO:0019887 | protein kinase regulator activity | 17 | 1009 | 105 | 25149 | 5.41e-06 | 0.02 | 0.00 | 4.0 |
89 | Level5 | GO:0001664 | G\-protein\-coupled receptor binding | 16 | 1010 | 96 | 25158 | 7.33e-06 | 0.02 | 0.00 | 4.1 |
90 | Level4 | GO:0019838 | growth factor binding | 17 | 1009 | 108 | 25146 | 7.54e-06 | 0.02 | 0.00 | 3.9 |
91 | Level5 | GO:0004866 | endopeptidase inhibitor activity | 22 | 1004 | 174 | 25080 | 9.19e-06 | 0.02 | 0.01 | 3.1 |
92 | Level5 | GO:0008234 | cysteine\-type peptidase activity | 22 | 1004 | 174 | 25080 | 9.19e-06 | 0.02 | 0.01 | 3.1 |
93 | Level4 | GO:0016860 | intramolecular oxidoreductase activity | 11 | 1015 | 47 | 25207 | 1.29e-05 | 0.01 | 0.00 | 5.8 |
94 | Level5 | GO:0008237 | metallopeptidase activity | 26 | 1000 | 237 | 25017 | 1.49e-05 | 0.03 | 0.01 | 2.7 |
95 | Level4 | GO:0030414 | protease inhibitor activity | 22 | 1004 | 181 | 25073 | 1.61e-05 | 0.02 | 0.01 | 3.0 |
96 | Level5 | GO:0016820 | hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances | 21 | 1005 | 169 | 25085 | 1.84e-05 | 0.02 | 0.01 | 3.1 |
97 | Level4 | GO:0051219 | phosphoprotein binding | 7 | 1019 | 16 | 25238 | 1.92e-05 | 0.01 | 0.00 | 10.8 |
98 | Level4 | GO:0005246 | calcium channel regulator activity | 7 | 1019 | 16 | 25238 | 1.92e-05 | 0.01 | 0.00 | 10.8 |
99 | Level4 | GO:0004602 | glutathione peroxidase activity | 6 | 1020 | 10 | 25244 | 2.00e-05 | 0.01 | 0.00 | 14.8 |
100 | Level4 | GO:0003677 | DNA binding | 157 | 869 | 2749 | 22505 | 2.36e-05 | 0.15 | 0.11 | 1.4 |
101 | Level4 | GO:0016651 | oxidoreductase activity\, acting on NADH or NADPH | 13 | 1013 | 72 | 25182 | 2.47e-05 | 0.01 | 0.00 | 4.4 |
102 | Level4 | GO:0019210 | kinase inhibitor activity | 10 | 1016 | 42 | 25212 | 2.80e-05 | 0.01 | 0.00 | 5.9 |
103 | Level5 | GO:0050664 | oxidoreductase activity\, acting on NADH or NADPH\, with oxygen as acceptor | 5 | 1021 | 6 | 25248 | 3.41e-05 | 0.00 | 0.00 | 20.5 |
104 | Level5 | GO:0015144 | carbohydrate transmembrane transporter activity | 11 | 1015 | 56 | 25198 | 5.28e-05 | 0.01 | 0.00 | 4.8 |
105 | Level4 | GO:0005496 | steroid binding | 14 | 1012 | 90 | 25164 | 5.29e-05 | 0.01 | 0.00 | 3.8 |
106 | Level5 | GO:0016836 | hydro\-lyase activity | 12 | 1014 | 67 | 25187 | 5.40e-05 | 0.01 | 0.00 | 4.4 |
107 | Level3 | GO:0003702 | RNA polymerase II transcription factor activity | 27 | 999 | 271 | 24983 | 5.47e-05 | 0.03 | 0.01 | 2.5 |
108 | Level4 | GO:0043560 | insulin receptor substrate binding | 5 | 1021 | 7 | 25247 | 5.66e-05 | 0.00 | 0.00 | 17.6 |
109 | Level4 | GO:0016504 | protease activator activity | 7 | 1019 | 21 | 25233 | 7.80e-05 | 0.01 | 0.00 | 8.2 |
110 | Level4 | GO:0001948 | glycoprotein binding | 5 | 1021 | 8 | 25246 | 8.90e-05 | 0.00 | 0.00 | 15.4 |
111 | Level5 | GO:0045309 | protein phosphorylated amino acid binding | 5 | 1021 | 8 | 25246 | 8.90e-05 | 0.00 | 0.00 | 15.4 |
112 | Level4 | GO:0008034 | lipoprotein binding | 8 | 1018 | 30 | 25224 | 9.04e-05 | 0.01 | 0.00 | 6.6 |
113 | Level4 | GO:0005516 | calmodulin binding | 20 | 1006 | 177 | 25077 | 9.62e-05 | 0.02 | 0.01 | 2.8 |
114 | Level5 | GO:0004860 | protein kinase inhibitor activity | 9 | 1017 | 40 | 25214 | 1.02e-04 | 0.01 | 0.00 | 5.5 |
115 | Level5 | GO:0016298 | lipase activity | 16 | 1010 | 124 | 25130 | 1.19e-04 | 0.02 | 0.00 | 3.2 |
116 | Level4 | GO:0016638 | oxidoreductase activity\, acting on the CH\-NH2 group of donors | 7 | 1019 | 23 | 25231 | 1.25e-04 | 0.01 | 0.00 | 7.5 |
117 | Level4 | GO:0017171 | serine hydrolase activity | 24 | 1002 | 238 | 25016 | 1.33e-04 | 0.02 | 0.01 | 2.5 |
118 | Level5 | GO:0004879 | ligand\-dependent nuclear receptor activity | 20 | 1006 | 186 | 25068 | 1.77e-04 | 0.02 | 0.01 | 2.6 |
119 | Level4 | GO:0008092 | cytoskeletal protein binding | 40 | 986 | 508 | 24746 | 1.90e-04 | 0.04 | 0.02 | 1.9 |
120 | Level3 | GO:0050840 | extracellular matrix binding | 5 | 1021 | 10 | 25244 | 1.94e-04 | 0.00 | 0.00 | 12.3 |
121 | Level4 | GO:0015036 | disulfide oxidoreductase activity | 6 | 1020 | 18 | 25236 | 2.57e-04 | 0.01 | 0.00 | 8.2 |
122 | Level5 | GO:0016831 | carboxy\-lyase activity | 8 | 1018 | 36 | 25218 | 2.67e-04 | 0.01 | 0.00 | 5.5 |
123 | Level5 | GO:0008236 | serine\-type peptidase activity | 23 | 1003 | 237 | 25017 | 2.71e-04 | 0.02 | 0.01 | 2.4 |
124 | Level4 | GO:0016801 | hydrolase activity\, acting on ether bonds | 5 | 1021 | 11 | 25243 | 2.74e-04 | 0.00 | 0.00 | 11.2 |
125 | Level4 | GO:0005518 | collagen binding | 7 | 1019 | 27 | 25227 | 2.89e-04 | 0.01 | 0.00 | 6.4 |
126 | Level5 | GO:0051287 | NAD binding | 9 | 1017 | 47 | 25207 | 2.96e-04 | 0.01 | 0.00 | 4.7 |
127 | Level3 | GO:0042562 | hormone binding | 8 | 1018 | 37 | 25217 | 3.13e-04 | 0.01 | 0.00 | 5.3 |
128 | Level5 | GO:0003995 | acyl\-CoA dehydrogenase activity | 6 | 1020 | 19 | 25235 | 3.26e-04 | 0.01 | 0.00 | 7.8 |
129 | Level4 | GO:0005319 | lipid transporter activity | 13 | 1013 | 96 | 25158 | 3.31e-04 | 0.01 | 0.00 | 3.3 |
130 | Level4 | GO:0016830 | carbon\-carbon lyase activity | 9 | 1017 | 48 | 25206 | 3.39e-04 | 0.01 | 0.00 | 4.6 |
131 | Level3 | GO:0051540 | metal cluster binding | 10 | 1016 | 60 | 25194 | 3.73e-04 | 0.01 | 0.00 | 4.1 |
132 | Level4 | GO:0051536 | iron\-sulfur cluster binding | 10 | 1016 | 60 | 25194 | 3.73e-04 | 0.01 | 0.00 | 4.1 |
133 | Level5 | GO:0005159 | insulin\-like growth factor receptor binding | 5 | 1021 | 12 | 25242 | 3.75e-04 | 0.00 | 0.00 | 10.3 |
134 | Level4 | GO:0043236 | laminin binding | 4 | 1022 | 6 | 25248 | 4.02e-04 | 0.00 | 0.00 | 16.4 |
135 | Level4 | GO:0005543 | phospholipid binding | 17 | 1009 | 157 | 25097 | 4.89e-04 | 0.02 | 0.01 | 2.7 |
136 | Level4 | GO:0047485 | protein N\-terminus binding | 9 | 1017 | 51 | 25203 | 5.02e-04 | 0.01 | 0.00 | 4.3 |
137 | Level4 | GO:0005542 | folic acid binding | 5 | 1021 | 13 | 25241 | 5.03e-04 | 0.00 | 0.00 | 9.5 |
138 | Level5 | GO:0019965 | interleukin binding | 11 | 1015 | 75 | 25179 | 5.12e-04 | 0.01 | 0.00 | 3.6 |
139 | Level5 | GO:0016714 | oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced pteridine as one donor\, and incorporation of one atom of oxygen | 4 | 1022 | 7 | 25247 | 6.12e-04 | 0.00 | 0.00 | 14.1 |
140 | Level5 | GO:0015075 | ion transmembrane transporter activity | 69 | 957 | 1096 | 24158 | 6.22e-04 | 0.07 | 0.04 | 1.5 |
141 | Level5 | GO:0016712 | oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced flavin or flavoprotein as one donor\, and incorporation of one atom of oxygen | 8 | 1018 | 42 | 25212 | 6.57e-04 | 0.01 | 0.00 | 4.7 |
142 | Level3 | GO:0043028 | caspase regulator activity | 6 | 1020 | 23 | 25231 | 7.66e-04 | 0.01 | 0.00 | 6.4 |
143 | Level5 | GO:0005158 | insulin receptor binding | 6 | 1020 | 23 | 25231 | 7.66e-04 | 0.01 | 0.00 | 6.4 |
144 | Level4 | GO:0019992 | diacylglycerol binding | 10 | 1016 | 67 | 25187 | 8.06e-04 | 0.01 | 0.00 | 3.7 |
145 | Level4 | GO:0016645 | oxidoreductase activity\, acting on the CH\-NH group of donors | 7 | 1019 | 33 | 25221 | 8.17e-04 | 0.01 | 0.00 | 5.2 |
146 | Level5 | GO:0010181 | FMN binding | 5 | 1021 | 15 | 25239 | 8.53e-04 | 0.00 | 0.00 | 8.2 |
147 | Level5 | GO:0004368 | glycerol\-3\-phosphate dehydrogenase activity | 4 | 1022 | 8 | 25246 | 8.89e-04 | 0.00 | 0.00 | 12.3 |
148 | Level3 | GO:0008047 | enzyme activator activity | 30 | 996 | 372 | 24882 | 9.78e-04 | 0.03 | 0.01 | 2.0 |
149 | Level5 | GO:0005178 | integrin binding | 9 | 1017 | 57 | 25197 | 1.02e-03 | 0.01 | 0.00 | 3.9 |
150 | Level3 | GO:0003682 | chromatin binding | 15 | 1011 | 139 | 25115 | 1.06e-03 | 0.01 | 0.01 | 2.7 |
151 | Level4 | GO:0008656 | caspase activator activity | 5 | 1021 | 16 | 25238 | 1.08e-03 | 0.00 | 0.00 | 7.7 |
152 | Level3 | GO:0042910 | xenobiotic transporter activity | 3 | 1023 | 3 | 25251 | 1.09e-03 | 0.00 | 0.00 | 24.6 |
153 | Level4 | GO:0043295 | glutathione binding | 3 | 1023 | 3 | 25251 | 1.09e-03 | 0.00 | 0.00 | 24.6 |
154 | Level5 | GO:0051539 | 4 iron\, 4 sulfur cluster binding | 6 | 1020 | 25 | 25229 | 1.11e-03 | 0.01 | 0.00 | 5.9 |
155 | Level4 | GO:0016866 | intramolecular transferase activity | 9 | 1017 | 59 | 25195 | 1.27e-03 | 0.01 | 0.00 | 3.8 |
156 | Level4 | GO:0016741 | transferase activity\, transferring one\-carbon groups | 18 | 1008 | 187 | 25067 | 1.47e-03 | 0.02 | 0.01 | 2.4 |
157 | Level2 | GO:0015457 | auxiliary transport protein activity | 8 | 1018 | 49 | 25205 | 1.59e-03 | 0.01 | 0.00 | 4.0 |
158 | Level5 | GO:0030169 | low\-density lipoprotein binding | 5 | 1021 | 18 | 25236 | 1.68e-03 | 0.00 | 0.00 | 6.8 |
159 | Level5 | GO:0016641 | oxidoreductase activity\, acting on the CH\-NH2 group of donors\, oxygen as acceptor | 5 | 1021 | 18 | 25236 | 1.68e-03 | 0.00 | 0.00 | 6.8 |
160 | Level5 | GO:0016505 | apoptotic protease activator activity | 5 | 1021 | 18 | 25236 | 1.68e-03 | 0.00 | 0.00 | 6.8 |
161 | Level5 | GO:0003779 | actin binding | 27 | 999 | 343 | 24911 | 1.74e-03 | 0.03 | 0.01 | 1.9 |
162 | Level4 | GO:0016721 | oxidoreductase activity\, acting on superoxide radicals as acceptor | 3 | 1023 | 4 | 25250 | 1.85e-03 | 0.00 | 0.00 | 18.5 |
163 | Level4 | GO:0015239 | multidrug transporter activity | 3 | 1023 | 4 | 25250 | 1.85e-03 | 0.00 | 0.00 | 18.5 |
164 | Level5 | GO:0004784 | superoxide dismutase activity | 3 | 1023 | 4 | 25250 | 1.85e-03 | 0.00 | 0.00 | 18.5 |
165 | Level5 | GO:0000104 | succinate dehydrogenase activity | 3 | 1023 | 4 | 25250 | 1.85e-03 | 0.00 | 0.00 | 18.5 |
166 | Level4 | GO:0016769 | transferase activity\, transferring nitrogenous groups | 7 | 1019 | 39 | 25215 | 1.92e-03 | 0.01 | 0.00 | 4.4 |
167 | Level4 | GO:0016566 | specific transcriptional repressor activity | 5 | 1021 | 19 | 25235 | 2.05e-03 | 0.00 | 0.00 | 6.5 |
168 | Level3 | GO:0005199 | structural constituent of cell wall | 10 | 1016 | 77 | 25177 | 2.07e-03 | 0.01 | 0.00 | 3.2 |
169 | Level4 | GO:0030551 | cyclic nucleotide binding | 6 | 1020 | 29 | 25225 | 2.15e-03 | 0.01 | 0.00 | 5.1 |
170 | Level5 | GO:0005520 | insulin\-like growth factor binding | 6 | 1020 | 29 | 25225 | 2.15e-03 | 0.01 | 0.00 | 5.1 |
171 | Level5 | GO:0043566 | structure\-specific DNA binding | 13 | 1013 | 121 | 25133 | 2.30e-03 | 0.01 | 0.00 | 2.6 |
172 | Level5 | GO:0008168 | methyltransferase activity | 17 | 1009 | 181 | 25073 | 2.41e-03 | 0.02 | 0.01 | 2.3 |
173 | Level4 | GO:0015002 | heme\-copper terminal oxidase activity | 6 | 1020 | 30 | 25224 | 2.49e-03 | 0.01 | 0.00 | 4.9 |
174 | Level4 | GO:0016675 | oxidoreductase activity\, acting on heme group of donors | 6 | 1020 | 30 | 25224 | 2.49e-03 | 0.01 | 0.00 | 4.9 |
175 | Level5 | GO:0004129 | cytochrome\-c oxidase activity | 6 | 1020 | 30 | 25224 | 2.49e-03 | 0.01 | 0.00 | 4.9 |
176 | Level5 | GO:0016676 | oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor | 6 | 1020 | 30 | 25224 | 2.49e-03 | 0.01 | 0.00 | 4.9 |
177 | Level5 | GO:0002020 | protease binding | 3 | 1023 | 5 | 25249 | 2.87e-03 | 0.00 | 0.00 | 14.8 |
178 | Level5 | GO:0030165 | PDZ domain binding | 6 | 1020 | 31 | 25223 | 2.88e-03 | 0.01 | 0.00 | 4.8 |
179 | Level4 | GO:0001540 | beta\-amyloid binding | 4 | 1022 | 12 | 25242 | 2.88e-03 | 0.00 | 0.00 | 8.2 |
180 | Level5 | GO:0005154 | epidermal growth factor receptor binding | 4 | 1022 | 12 | 25242 | 2.88e-03 | 0.00 | 0.00 | 8.2 |
181 | Level5 | GO:0015250 | water channel activity | 4 | 1022 | 12 | 25242 | 2.88e-03 | 0.00 | 0.00 | 8.2 |
182 | Level5 | GO:0015035 | protein disulfide oxidoreductase activity | 4 | 1022 | 12 | 25242 | 2.88e-03 | 0.00 | 0.00 | 8.2 |
183 | Level4 | GO:0016597 | amino acid binding | 5 | 1021 | 21 | 25233 | 2.98e-03 | 0.00 | 0.00 | 5.9 |
184 | Level5 | GO:0033558 | protein deacetylase activity | 5 | 1021 | 21 | 25233 | 2.98e-03 | 0.00 | 0.00 | 5.9 |
185 | Level2 | GO:0005198 | structural molecule activity | 62 | 964 | 1026 | 24228 | 2.99e-03 | 0.06 | 0.04 | 1.5 |
186 | Level4 | GO:0005504 | fatty acid binding | 6 | 1020 | 32 | 25222 | 3.31e-03 | 0.01 | 0.00 | 4.6 |
187 | Level5 | GO:0019865 | immunoglobulin binding | 5 | 1021 | 22 | 25232 | 3.54e-03 | 0.00 | 0.00 | 5.6 |
188 | Level3 | GO:0043176 | amine binding | 9 | 1017 | 70 | 25184 | 3.62e-03 | 0.01 | 0.00 | 3.2 |
189 | Level5 | GO:0019956 | chemokine binding | 9 | 1017 | 70 | 25184 | 3.62e-03 | 0.01 | 0.00 | 3.2 |
190 | Level3 | GO:0008367 | bacterial binding | 4 | 1022 | 13 | 25241 | 3.66e-03 | 0.00 | 0.00 | 7.6 |
191 | Level4 | GO:0005372 | water transporter activity | 4 | 1022 | 13 | 25241 | 3.66e-03 | 0.00 | 0.00 | 7.6 |
192 | Level4 | GO:0043621 | protein self\-association | 4 | 1022 | 13 | 25241 | 3.66e-03 | 0.00 | 0.00 | 7.6 |
193 | Level5 | GO:0030228 | lipoprotein receptor activity | 4 | 1022 | 13 | 25241 | 3.66e-03 | 0.00 | 0.00 | 7.6 |
194 | Level3 | GO:0016247 | channel regulator activity | 7 | 1019 | 45 | 25209 | 3.91e-03 | 0.01 | 0.00 | 3.8 |
195 | Level3 | GO:0016874 | ligase activity | 32 | 994 | 449 | 24805 | 3.94e-03 | 0.03 | 0.02 | 1.8 |
196 | Level5 | GO:0030508 | thiol\-disulfide exchange intermediate activity | 3 | 1023 | 6 | 25248 | 4.18e-03 | 0.00 | 0.00 | 12.3 |
197 | Level5 | GO:0016803 | ether hydrolase activity | 3 | 1023 | 6 | 25248 | 4.18e-03 | 0.00 | 0.00 | 12.3 |
198 | Level5 | GO:0008483 | transaminase activity | 6 | 1020 | 34 | 25220 | 4.30e-03 | 0.01 | 0.00 | 4.3 |
199 | Level4 | GO:0016746 | transferase activity\, transferring acyl groups | 19 | 1007 | 227 | 25027 | 4.41e-03 | 0.02 | 0.01 | 2.1 |
200 | Level5 | GO:0015248 | sterol transporter activity | 4 | 1022 | 14 | 25240 | 4.56e-03 | 0.00 | 0.00 | 7.0 |
201 | Level5 | GO:0016747 | transferase activity\, transferring groups other than amino\-acyl groups | 18 | 1008 | 207 | 25047 | 4.58e-03 | 0.02 | 0.01 | 2.1 |
202 | Level3 | GO:0005200 | structural constituent of cytoskeleton | 12 | 1014 | 117 | 25137 | 4.68e-03 | 0.01 | 0.00 | 2.5 |
203 | Level3 | GO:0008307 | structural constituent of muscle | 7 | 1019 | 47 | 25207 | 4.84e-03 | 0.01 | 0.00 | 3.7 |
204 | Level3 | GO:0008430 | selenium binding | 5 | 1021 | 24 | 25230 | 4.89e-03 | 0.00 | 0.00 | 5.1 |
205 | Level4 | GO:0019213 | deacetylase activity | 5 | 1021 | 24 | 25230 | 4.89e-03 | 0.00 | 0.00 | 5.1 |
206 | Level5 | GO:0016775 | phosphotransferase activity\, nitrogenous group as acceptor | 5 | 1021 | 24 | 25230 | 4.89e-03 | 0.00 | 0.00 | 5.1 |
207 | Level4 | GO:0017046 | peptide hormone binding | 4 | 1022 | 15 | 25239 | 5.60e-03 | 0.00 | 0.00 | 6.6 |
208 | Level4 | GO:0008320 | protein transmembrane transporter activity | 5 | 1021 | 25 | 25229 | 5.68e-03 | 0.00 | 0.00 | 4.9 |
209 | Level3 | GO:0008147 | structural constituent of bone | 3 | 1023 | 7 | 25247 | 5.79e-03 | 0.00 | 0.00 | 10.5 |
210 | Level4 | GO:0030492 | hemoglobin binding | 3 | 1023 | 7 | 25247 | 5.79e-03 | 0.00 | 0.00 | 10.5 |
211 | Level4 | GO:0051920 | peroxiredoxin activity | 3 | 1023 | 7 | 25247 | 5.79e-03 | 0.00 | 0.00 | 10.5 |
212 | Level4 | GO:0016903 | oxidoreductase activity\, acting on the aldehyde or oxo group of donors | 6 | 1020 | 37 | 25217 | 6.19e-03 | 0.01 | 0.00 | 4.0 |
213 | Level3 | GO:0005201 | extracellular matrix structural constituent | 12 | 1014 | 122 | 25132 | 6.33e-03 | 0.01 | 0.00 | 2.4 |
214 | Level5 | GO:0051537 | 2 iron\, 2 sulfur cluster binding | 4 | 1022 | 16 | 25238 | 6.79e-03 | 0.00 | 0.00 | 6.2 |
215 | Level5 | GO:0030545 | receptor regulator activity | 4 | 1022 | 16 | 25238 | 6.79e-03 | 0.00 | 0.00 | 6.2 |
216 | Level5 | GO:0016811 | hydrolase activity\, acting on carbon\-nitrogen (but not peptide) bonds\, in linear amides | 8 | 1018 | 64 | 25190 | 6.91e-03 | 0.01 | 0.00 | 3.1 |
217 | Level5 | GO:0016818 | hydrolase activity\, acting on acid anhydrides\, in phosphorus\-containing anhydrides | 52 | 974 | 867 | 24387 | 7.12e-03 | 0.05 | 0.03 | 1.5 |
218 | Level5 | GO:0030552 | cAMP binding | 4 | 1022 | 17 | 25237 | 8.13e-03 | 0.00 | 0.00 | 5.8 |
219 | Level5 | GO:0009982 | pseudouridine synthase activity | 6 | 1020 | 40 | 25214 | 8.62e-03 | 0.01 | 0.00 | 3.7 |
220 | Level4 | GO:0017077 | oxidative phosphorylation uncoupler activity | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
221 | Level4 | GO:0060228 | phosphatidylcholine\-sterol O\-acyltransferase activator activity | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
222 | Level4 | GO:0045569 | TRAIL binding | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
223 | Level5 | GO:0045155 | electron transporter\, transferring electrons from CoQH2\-cytochrome c reductase complex and cytochrome c oxidase complex activity | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
224 | Level5 | GO:0043559 | insulin binding | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
225 | Level5 | GO:0004666 | prostaglandin\-endoperoxide synthase activity | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
226 | Level5 | GO:0004392 | heme oxygenase (decyclizing) activity | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
227 | Level5 | GO:0016635 | oxidoreductase activity\, acting on the CH\-CH group of donors\, quinone or related compound as acceptor | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
228 | Level5 | GO:0043237 | laminin\-1 binding | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
229 | Level5 | GO:0035226 | glutamate\-cysteine ligase catalytic subunit binding | 2 | 1024 | 2 | 25252 | 8.67e-03 | 0.00 | 0.00 | 24.6 |
230 | Level4 | GO:0016810 | hydrolase activity\, acting on carbon\-nitrogen (but not peptide) bonds | 13 | 1013 | 138 | 25116 | 8.78e-03 | 0.01 | 0.01 | 2.3 |
231 | Level4 | GO:0016817 | hydrolase activity\, acting on acid anhydrides | 52 | 974 | 869 | 24385 | 9.04e-03 | 0.05 | 0.03 | 1.5 |
232 | Level5 | GO:0004091 | carboxylesterase activity | 11 | 1015 | 113 | 25141 | 9.35e-03 | 0.01 | 0.00 | 2.4 |
233 | Level5 | GO:0016709 | oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, NADH or NADPH as one donor\, and incorporation of one atom of oxygen | 6 | 1020 | 41 | 25213 | 9.56e-03 | 0.01 | 0.00 | 3.6 |
234 | Level3 | GO:0043021 | ribonucleoprotein binding | 4 | 1022 | 18 | 25236 | 9.63e-03 | 0.00 | 0.00 | 5.5 |
235 | Level4 | GO:0005344 | oxygen transporter activity | 4 | 1022 | 18 | 25236 | 9.63e-03 | 0.00 | 0.00 | 5.5 |
236 | Level5 | GO:0008395 | steroid hydroxylase activity | 4 | 1022 | 18 | 25236 | 9.63e-03 | 0.00 | 0.00 | 5.5 |
237 | Level5 | GO:0008603 | cAMP\-dependent protein kinase regulator activity | 5 | 1021 | 29 | 25225 | 9.75e-03 | 0.00 | 0.00 | 4.2 |
238 | Level4 | GO:0035014 | phosphoinositide 3\-kinase regulator activity | 3 | 1023 | 9 | 25245 | 1.00e-02 | 0.00 | 0.00 | 8.2 |
239 | Level4 | GO:0043022 | ribosome binding | 3 | 1023 | 9 | 25245 | 1.00e-02 | 0.00 | 0.00 | 8.2 |
240 | Level4 | GO:0005527 | macrolide binding | 3 | 1023 | 9 | 25245 | 1.00e-02 | 0.00 | 0.00 | 8.2 |
241 | Level5 | GO:0016624 | oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, disulfide as acceptor | 3 | 1023 | 9 | 25245 | 1.00e-02 | 0.00 | 0.00 | 8.2 |
242 | Level5 | GO:0043120 | tumor necrosis factor binding | 3 | 1023 | 9 | 25245 | 1.00e-02 | 0.00 | 0.00 | 8.2 |
243 | Level5 | GO:0003906 | DNA\-(apurinic or apyrimidinic site) lyase activity | 3 | 1023 | 9 | 25245 | 1.00e-02 | 0.00 | 0.00 | 8.2 |
244 | Level5 | GO:0005528 | FK506 binding | 3 | 1023 | 9 | 25245 | 1.00e-02 | 0.00 | 0.00 | 8.2 |
245 | Level5 | GO:0051427 | hormone receptor binding | 8 | 1018 | 69 | 25185 | 1.03e-02 | 0.01 | 0.00 | 2.9 |
246 | Level5 | GO:0016628 | oxidoreductase activity\, acting on the CH\-CH group of donors\, NAD or NADP as acceptor | 7 | 1019 | 55 | 25199 | 1.03e-02 | 0.01 | 0.00 | 3.1 |
247 | Level5 | GO:0004364 | glutathione transferase activity | 5 | 1021 | 31 | 25223 | 1.24e-02 | 0.00 | 0.00 | 4.0 |
248 | Level4 | GO:0016885 | ligase activity\, forming carbon\-carbon bonds | 3 | 1023 | 10 | 25244 | 1.26e-02 | 0.00 | 0.00 | 7.4 |
249 | Level5 | GO:0016717 | oxidoreductase activity\, acting on paired donors\, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water | 3 | 1023 | 10 | 25244 | 1.26e-02 | 0.00 | 0.00 | 7.4 |
250 | Level5 | GO:0016862 | intramolecular oxidoreductase activity\, interconverting keto\- and enol\-groups | 3 | 1023 | 10 | 25244 | 1.26e-02 | 0.00 | 0.00 | 7.4 |
251 | Level4 | GO:0016667 | oxidoreductase activity\, acting on sulfur group of donors | 4 | 1022 | 20 | 25234 | 1.32e-02 | 0.00 | 0.00 | 4.9 |
252 | Level5 | GO:0015026 | coreceptor activity | 4 | 1022 | 20 | 25234 | 1.32e-02 | 0.00 | 0.00 | 4.9 |
253 | Level4 | GO:0030332 | cyclin binding | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
254 | Level5 | GO:0015037 | peptide disulfide oxidoreductase activity | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
255 | Level5 | GO:0034190 | apolipoprotein receptor binding | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
256 | Level5 | GO:0048156 | tau protein binding | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
257 | Level5 | GO:0051400 | BH domain binding | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
258 | Level5 | GO:0016724 | oxidoreductase activity\, oxidizing metal ions\, oxygen as acceptor | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
259 | Level5 | GO:0004738 | pyruvate dehydrogenase activity | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
260 | Level5 | GO:0031432 | titin binding | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
261 | Level5 | GO:0008410 | CoA\-transferase activity | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
262 | Level5 | GO:0019855 | calcium channel inhibitor activity | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
263 | Level5 | GO:0031210 | phosphatidylcholine binding | 2 | 1024 | 3 | 25251 | 1.41e-02 | 0.00 | 0.00 | 16.4 |
264 | Level3 | GO:0042165 | neurotransmitter binding | 20 | 1006 | 272 | 24982 | 1.42e-02 | 0.02 | 0.01 | 1.8 |
265 | Level5 | GO:0017022 | myosin binding | 4 | 1022 | 21 | 25233 | 1.52e-02 | 0.00 | 0.00 | 4.7 |
266 | Level4 | GO:0016879 | ligase activity\, forming carbon\-nitrogen bonds | 19 | 1007 | 250 | 25004 | 1.59e-02 | 0.02 | 0.01 | 1.9 |
267 | Level3 | GO:0042277 | peptide binding | 32 | 994 | 499 | 24755 | 1.67e-02 | 0.03 | 0.02 | 1.6 |
268 | Level5 | GO:0015450 | P\-P\-bond\-hydrolysis\-driven protein transmembrane transporter activity | 4 | 1022 | 22 | 25232 | 1.74e-02 | 0.00 | 0.00 | 4.5 |
269 | Level5 | GO:0022884 | macromolecule transmembrane transporter activity | 4 | 1022 | 22 | 25232 | 1.74e-02 | 0.00 | 0.00 | 4.5 |
270 | Level5 | GO:0016646 | oxidoreductase activity\, acting on the CH\-NH group of donors\, NAD or NADP as acceptor | 4 | 1022 | 23 | 25231 | 1.98e-02 | 0.00 | 0.00 | 4.3 |
271 | Level4 | GO:0048154 | S100 beta binding | 2 | 1024 | 4 | 25250 | 2.06e-02 | 0.00 | 0.00 | 12.3 |
272 | Level4 | GO:0034185 | apolipoprotein binding | 2 | 1024 | 4 | 25250 | 2.06e-02 | 0.00 | 0.00 | 12.3 |
273 | Level4 | GO:0016822 | hydrolase activity\, acting on acid carbon\-carbon bonds | 2 | 1024 | 4 | 25250 | 2.06e-02 | 0.00 | 0.00 | 12.3 |
274 | Level5 | GO:0005062 | hematopoietin/interferon\-class (D200\-domain) cytokine receptor signal transducer activity | 2 | 1024 | 4 | 25250 | 2.06e-02 | 0.00 | 0.00 | 12.3 |
275 | Level5 | GO:0008294 | calcium\- and calmodulin\-responsive adenylate cyclase activity | 2 | 1024 | 4 | 25250 | 2.06e-02 | 0.00 | 0.00 | 12.3 |
276 | Level5 | GO:0051117 | ATPase binding | 2 | 1024 | 4 | 25250 | 2.06e-02 | 0.00 | 0.00 | 12.3 |
277 | Level5 | GO:0042975 | peroxisome proliferator activated receptor binding | 2 | 1024 | 4 | 25250 | 2.06e-02 | 0.00 | 0.00 | 12.3 |
278 | Level5 | GO:0016823 | hydrolase activity\, acting on acid carbon\-carbon bonds\, in ketonic substances | 2 | 1024 | 4 | 25250 | 2.06e-02 | 0.00 | 0.00 | 12.3 |
279 | Level5 | GO:0005160 | transforming growth factor beta receptor binding | 3 | 1023 | 13 | 25241 | 2.27e-02 | 0.00 | 0.00 | 5.7 |
280 | Level5 | GO:0004518 | nuclease activity | 14 | 1012 | 178 | 25076 | 2.30e-02 | 0.01 | 0.01 | 1.9 |
281 | Level4 | GO:0016765 | transferase activity\, transferring alkyl or aryl (other than methyl) groups | 7 | 1019 | 66 | 25188 | 2.37e-02 | 0.01 | 0.00 | 2.6 |
282 | Level5 | GO:0019902 | phosphatase binding | 4 | 1022 | 25 | 25229 | 2.52e-02 | 0.00 | 0.00 | 3.9 |
283 | Level5 | GO:0016799 | hydrolase activity\, hydrolyzing N\-glycosyl compounds | 4 | 1022 | 25 | 25229 | 2.52e-02 | 0.00 | 0.00 | 3.9 |
284 | Level5 | GO:0005066 | transmembrane receptor protein tyrosine kinase signaling protein activity | 3 | 1023 | 14 | 25240 | 2.68e-02 | 0.00 | 0.00 | 5.3 |
285 | Level3 | GO:0030235 | nitric\-oxide synthase regulator activity | 2 | 1024 | 5 | 25249 | 2.81e-02 | 0.00 | 0.00 | 9.8 |
286 | Level4 | GO:0015643 | toxin binding | 2 | 1024 | 5 | 25249 | 2.81e-02 | 0.00 | 0.00 | 9.8 |
287 | Level4 | GO:0001530 | lipopolysaccharide binding | 2 | 1024 | 5 | 25249 | 2.81e-02 | 0.00 | 0.00 | 9.8 |
288 | Level4 | GO:0005497 | androgen binding | 2 | 1024 | 5 | 25249 | 2.81e-02 | 0.00 | 0.00 | 9.8 |
289 | Level5 | GO:0016802 | trialkylsulfonium hydrolase activity | 2 | 1024 | 5 | 25249 | 2.81e-02 | 0.00 | 0.00 | 9.8 |
290 | Level3 | GO:0008144 | drug binding | 4 | 1022 | 26 | 25228 | 2.82e-02 | 0.00 | 0.00 | 3.8 |
291 | Level5 | GO:0032934 | sterol binding | 4 | 1022 | 26 | 25228 | 2.82e-02 | 0.00 | 0.00 | 3.8 |
292 | Level3 | GO:0050824 | water binding | 15 | 1011 | 196 | 25058 | 2.91e-02 | 0.01 | 0.01 | 1.9 |
293 | Level4 | GO:0050825 | ice binding | 15 | 1011 | 196 | 25058 | 2.91e-02 | 0.01 | 0.01 | 1.9 |
294 | Level5 | GO:0000062 | acyl\-CoA binding | 3 | 1023 | 15 | 25239 | 3.12e-02 | 0.00 | 0.00 | 4.9 |
295 | Level5 | GO:0003684 | damaged DNA binding | 6 | 1020 | 55 | 25199 | 3.14e-02 | 0.01 | 0.00 | 2.7 |
296 | Level5 | GO:0017124 | SH3 domain binding | 4 | 1022 | 27 | 25227 | 3.14e-02 | 0.00 | 0.00 | 3.6 |
297 | Level3 | GO:0009975 | cyclase activity | 4 | 1022 | 28 | 25226 | 3.49e-02 | 0.00 | 0.00 | 3.5 |
298 | Level4 | GO:0016849 | phosphorus\-oxygen lyase activity | 4 | 1022 | 28 | 25226 | 3.49e-02 | 0.00 | 0.00 | 3.5 |
299 | Level5 | GO:0016620 | oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor | 4 | 1022 | 28 | 25226 | 3.49e-02 | 0.00 | 0.00 | 3.5 |
300 | Level5 | GO:0016868 | intramolecular transferase activity\, phosphotransferases | 3 | 1023 | 16 | 25238 | 3.60e-02 | 0.00 | 0.00 | 4.6 |
301 | Level4 | GO:0005522 | profilin binding | 2 | 1024 | 6 | 25248 | 3.65e-02 | 0.00 | 0.00 | 8.2 |
302 | Level4 | GO:0001846 | opsonin binding | 2 | 1024 | 6 | 25248 | 3.65e-02 | 0.00 | 0.00 | 8.2 |
303 | Level4 | GO:0009374 | biotin binding | 2 | 1024 | 6 | 25248 | 3.65e-02 | 0.00 | 0.00 | 8.2 |
304 | Level5 | GO:0035035 | histone acetyltransferase binding | 2 | 1024 | 6 | 25248 | 3.65e-02 | 0.00 | 0.00 | 8.2 |
305 | Level5 | GO:0016783 | sulfurtransferase activity | 2 | 1024 | 6 | 25248 | 3.65e-02 | 0.00 | 0.00 | 8.2 |
306 | Level4 | GO:0016798 | hydrolase activity\, acting on glycosyl bonds | 12 | 1014 | 152 | 25102 | 3.86e-02 | 0.01 | 0.01 | 1.9 |
307 | Level4 | GO:0016846 | carbon\-sulfur lyase activity | 3 | 1023 | 17 | 25237 | 4.12e-02 | 0.00 | 0.00 | 4.3 |
308 | Level4 | GO:0032182 | small conjugating protein binding | 3 | 1023 | 17 | 25237 | 4.12e-02 | 0.00 | 0.00 | 4.3 |
309 | Level5 | GO:0016863 | intramolecular oxidoreductase activity\, transposing C=C bonds | 3 | 1023 | 17 | 25237 | 4.12e-02 | 0.00 | 0.00 | 4.3 |
310 | Level4 | GO:0030594 | neurotransmitter receptor activity | 18 | 1008 | 268 | 24986 | 4.45e-02 | 0.02 | 0.01 | 1.7 |
311 | Level2 | GO:0008369 | obsolete molecular function | 10 | 1016 | 126 | 25128 | 4.51e-02 | 0.01 | 0.00 | 2.0 |
312 | Level4 | GO:0005529 | sugar binding | 16 | 1010 | 231 | 25023 | 4.56e-02 | 0.02 | 0.01 | 1.7 |
313 | Level3 | GO:0042301 | phosphate binding | 2 | 1024 | 7 | 25247 | 4.57e-02 | 0.00 | 0.00 | 7.0 |
314 | Level4 | GO:0016725 | oxidoreductase activity\, acting on CH or CH2 groups | 2 | 1024 | 7 | 25247 | 4.57e-02 | 0.00 | 0.00 | 7.0 |
315 | Level5 | GO:0016668 | oxidoreductase activity\, acting on sulfur group of donors\, NAD or NADP as acceptor | 2 | 1024 | 7 | 25247 | 4.57e-02 | 0.00 | 0.00 | 7.0 |
316 | Level5 | GO:0016713 | oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced iron\-sulfur protein as one donor\, and incorporation of one atom of oxygen | 2 | 1024 | 7 | 25247 | 4.57e-02 | 0.00 | 0.00 | 7.0 |
317 | Level5 | GO:0005071 | transmembrane receptor protein serine/threonine kinase signaling protein activity | 2 | 1024 | 7 | 25247 | 4.57e-02 | 0.00 | 0.00 | 7.0 |
318 | Level5 | GO:0005123 | death receptor binding | 2 | 1024 | 7 | 25247 | 4.57e-02 | 0.00 | 0.00 | 7.0 |
319 | Level5 | GO:0016671 | oxidoreductase activity\, acting on sulfur group of donors\, disulfide as acceptor | 2 | 1024 | 7 | 25247 | 4.57e-02 | 0.00 | 0.00 | 7.0 |
320 | Level5 | GO:0003755 | peptidyl\-prolyl cis\-trans isomerase activity | 5 | 1021 | 46 | 25208 | 4.81e-02 | 0.00 | 0.00 | 2.7 |
321 | Level4 | GO:0003704 | specific RNA polymerase II transcription factor activity | 5 | 1021 | 47 | 25207 | 5.16e-02 | 0.00 | 0.00 | 2.6 |
322 | Level3 | GO:0060090 | molecular adaptor activity | 6 | 1020 | 63 | 25191 | 5.23e-02 | 0.01 | 0.00 | 2.3 |
323 | Level5 | GO:0051059 | NF\-kappaB binding | 4 | 1022 | 33 | 25221 | 5.51e-02 | 0.00 | 0.00 | 3.0 |
324 | Level4 | GO:0016859 | cis\-trans isomerase activity | 5 | 1021 | 48 | 25206 | 5.52e-02 | 0.00 | 0.00 | 2.6 |
325 | Level3 | GO:0008641 | small protein activating enzyme activity | 2 | 1024 | 8 | 25246 | 5.57e-02 | 0.00 | 0.00 | 6.2 |
326 | Level5 | GO:0016653 | oxidoreductase activity\, acting on NADH or NADPH\, heme protein as acceptor | 2 | 1024 | 8 | 25246 | 5.57e-02 | 0.00 | 0.00 | 6.2 |
327 | Level3 | GO:0000146 | microfilament motor activity | 3 | 1023 | 20 | 25234 | 5.88e-02 | 0.00 | 0.00 | 3.7 |
328 | Level4 | GO:0051087 | chaperone binding | 3 | 1023 | 20 | 25234 | 5.88e-02 | 0.00 | 0.00 | 3.7 |
329 | Level4 | GO:0046332 | SMAD binding | 3 | 1023 | 20 | 25234 | 5.88e-02 | 0.00 | 0.00 | 3.7 |
330 | Level5 | GO:0003916 | DNA topoisomerase activity | 4 | 1022 | 35 | 25219 | 6.46e-02 | 0.00 | 0.00 | 2.8 |
331 | Level4 | GO:0016722 | oxidoreductase activity\, oxidizing metal ions | 2 | 1024 | 9 | 25245 | 6.63e-02 | 0.00 | 0.00 | 5.5 |
332 | Level5 | GO:0016421 | CoA carboxylase activity | 2 | 1024 | 9 | 25245 | 6.63e-02 | 0.00 | 0.00 | 5.5 |
333 | Level5 | GO:0016615 | malate dehydrogenase activity | 2 | 1024 | 9 | 25245 | 6.63e-02 | 0.00 | 0.00 | 5.5 |
334 | Level5 | GO:0032404 | mismatch repair complex binding | 2 | 1024 | 9 | 25245 | 6.63e-02 | 0.00 | 0.00 | 5.5 |
335 | Level5 | GO:0016864 | intramolecular oxidoreductase activity\, transposing S\-S bonds | 2 | 1024 | 9 | 25245 | 6.63e-02 | 0.00 | 0.00 | 5.5 |
336 | Level5 | GO:0016405 | CoA\-ligase activity | 2 | 1024 | 9 | 25245 | 6.63e-02 | 0.00 | 0.00 | 5.5 |
337 | Level5 | GO:0050811 | GABA receptor binding | 2 | 1024 | 9 | 25245 | 6.63e-02 | 0.00 | 0.00 | 5.5 |
338 | Level4 | GO:0016701 | oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen | 6 | 1020 | 68 | 25186 | 6.89e-02 | 0.01 | 0.00 | 2.2 |
339 | Level5 | GO:0042287 | MHC protein binding | 3 | 1023 | 22 | 25232 | 7.21e-02 | 0.00 | 0.00 | 3.4 |
340 | Level4 | GO:0022803 | passive transmembrane transporter activity | 33 | 993 | 589 | 24665 | 7.42e-02 | 0.03 | 0.02 | 1.4 |
341 | Level5 | GO:0015267 | channel activity | 33 | 993 | 589 | 24665 | 7.42e-02 | 0.03 | 0.02 | 1.4 |
342 | Level3 | GO:0003676 | nucleic acid binding | 176 | 850 | 3812 | 21442 | 7.57e-02 | 0.17 | 0.15 | 1.1 |
343 | Level3 | GO:0004362 | glutathione\-disulfide reductase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
344 | Level3 | GO:0033237 | 11\-beta\-hydroxysteroid dehydrogenase (NADP\+) activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
345 | Level3 | GO:0046904 | calcium oxalate binding | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
346 | Level4 | GO:0016176 | superoxide\-generating NADPH oxidase activator activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
347 | Level4 | GO:0047066 | phospholipid\-hydroperoxide glutathione peroxidase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
348 | Level4 | GO:0019103 | pyrimidine nucleotide binding | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
349 | Level4 | GO:0030984 | kininogen binding | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
350 | Level4 | GO:0030613 | oxidoreductase activity\, acting on phosphorus or arsenic in donors | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
351 | Level5 | GO:0016727 | oxidoreductase activity\, acting on CH or CH2 groups\, oxygen as acceptor | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
352 | Level5 | GO:0046911 | metal chelating activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
353 | Level5 | GO:0004796 | thromboxane\-A synthase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
354 | Level5 | GO:0033130 | acetylcholine receptor binding | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
355 | Level5 | GO:0004148 | dihydrolipoyl dehydrogenase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
356 | Level5 | GO:0004736 | pyruvate carboxylase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
357 | Level5 | GO:0032183 | SUMO binding | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
358 | Level5 | GO:0009054 | electron acceptor activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
359 | Level5 | GO:0030567 | prothrombin activator activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
360 | Level5 | GO:0003958 | NADPH\-hemoprotein reductase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
361 | Level5 | GO:0043398 | HLH domain binding | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
362 | Level5 | GO:0050113 | inositol oxygenase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
363 | Level5 | GO:0047865 | dimethylglycine dehydrogenase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
364 | Level5 | GO:0008480 | sarcosine dehydrogenase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
365 | Level5 | GO:0032145 | succinate\-semialdehyde dehydrogenase binding | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
366 | Level5 | GO:0008794 | arsenate reductase (glutaredoxin) activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
367 | Level5 | GO:0030614 | oxidoreductase activity\, acting on phosphorus or arsenic in donors\, with disulfide as acceptor | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
368 | Level5 | GO:0004418 | hydroxymethylbilane synthase activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
369 | Level5 | GO:0042610 | CD8 receptor binding | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
370 | Level5 | GO:0015266 | protein channel activity | 1 | 1025 | 1 | 25253 | 7.66e-02 | 0.00 | 0.00 | 24.6 |
371 | Level4 | GO:0016840 | carbon\-nitrogen lyase activity | 2 | 1024 | 10 | 25244 | 7.76e-02 | 0.00 | 0.00 | 4.9 |
372 | Level4 | GO:0008093 | cytoskeletal adaptor activity | 2 | 1024 | 10 | 25244 | 7.76e-02 | 0.00 | 0.00 | 4.9 |
373 | Level5 | GO:0016774 | phosphotransferase activity\, carboxyl group as acceptor | 2 | 1024 | 10 | 25244 | 7.76e-02 | 0.00 | 0.00 | 4.9 |
374 | Level5 | GO:0015198 | oligopeptide transporter activity | 2 | 1024 | 10 | 25244 | 7.76e-02 | 0.00 | 0.00 | 4.9 |
375 | Level5 | GO:0016881 | acid\-amino acid ligase activity | 14 | 1012 | 208 | 25046 | 7.82e-02 | 0.01 | 0.01 | 1.7 |
376 | Level3 | GO:0015238 | drug transporter activity | 4 | 1022 | 38 | 25216 | 8.03e-02 | 0.00 | 0.00 | 2.6 |
377 | Level5 | GO:0016814 | hydrolase activity\, acting on carbon\-nitrogen (but not peptide) bonds\, in cyclic amidines | 4 | 1022 | 39 | 25215 | 8.60e-02 | 0.00 | 0.00 | 2.5 |
378 | Level3 | GO:0031406 | carboxylic acid binding | 2 | 1024 | 11 | 25243 | 8.94e-02 | 0.00 | 0.00 | 4.5 |
379 | Level5 | GO:0016634 | oxidoreductase activity\, acting on the CH\-CH group of donors\, oxygen as acceptor | 2 | 1024 | 11 | 25243 | 8.94e-02 | 0.00 | 0.00 | 4.5 |
380 | Level4 | GO:0016782 | transferase activity\, transferring sulfur\-containing groups | 5 | 1021 | 58 | 25196 | 9.92e-02 | 0.00 | 0.00 | 2.1 |
381 | Level3 | GO:0048503 | GPI anchor binding | 9 | 1017 | 118 | 25136 | 1.00e-01 | 0.01 | 0.00 | 1.9 |
382 | Level4 | GO:0004383 | guanylate cyclase activity | 2 | 1024 | 12 | 25242 | 1.02e-01 | 0.00 | 0.00 | 4.1 |
383 | Level4 | GO:0016248 | channel inhibitor activity | 2 | 1024 | 12 | 25242 | 1.02e-01 | 0.00 | 0.00 | 4.1 |
384 | Level5 | GO:0030553 | cGMP binding | 2 | 1024 | 12 | 25242 | 1.02e-01 | 0.00 | 0.00 | 4.1 |
385 | Level5 | GO:0050998 | nitric\-oxide synthase binding | 2 | 1024 | 12 | 25242 | 1.02e-01 | 0.00 | 0.00 | 4.1 |
386 | Level5 | GO:0016861 | intramolecular oxidoreductase activity\, interconverting aldoses and ketoses | 2 | 1024 | 12 | 25242 | 1.02e-01 | 0.00 | 0.00 | 4.1 |
387 | Level5 | GO:0008200 | ion channel inhibitor activity | 2 | 1024 | 12 | 25242 | 1.02e-01 | 0.00 | 0.00 | 4.1 |
388 | Level4 | GO:0016877 | ligase activity\, forming carbon\-sulfur bonds | 3 | 1023 | 27 | 25227 | 1.11e-01 | 0.00 | 0.00 | 2.7 |
389 | Level5 | GO:0019905 | syntaxin binding | 3 | 1023 | 27 | 25227 | 1.11e-01 | 0.00 | 0.00 | 2.7 |
390 | Level3 | GO:0002054 | nucleobase binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
391 | Level3 | GO:0030337 | DNA polymerase processivity factor activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
392 | Level3 | GO:0017163 | negative regulator of basal transcription activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
393 | Level3 | GO:0015460 | transport accessory protein activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
394 | Level3 | GO:0000150 | recombinase activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
395 | Level4 | GO:0004096 | catalase activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
396 | Level4 | GO:0019826 | oxygen sensor activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
397 | Level4 | GO:0008539 | proteasome inhibitor activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
398 | Level4 | GO:0048155 | S100 alpha binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
399 | Level4 | GO:0002060 | purine binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
400 | Level4 | GO:0001918 | farnesylated protein binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
401 | Level4 | GO:0043499 | eukaryotic cell surface binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
402 | Level4 | GO:0017129 | triglyceride binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
403 | Level4 | GO:0043008 | ATP\-dependent protein binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
404 | Level4 | GO:0004839 | ubiquitin activating enzyme activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
405 | Level4 | GO:0030611 | arsenate reductase activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
406 | Level4 | GO:0004447 | iodide peroxidase activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
407 | Level4 | GO:0045294 | alpha\-catenin binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
408 | Level5 | GO:0016726 | oxidoreductase activity\, acting on CH or CH2 groups\, NAD or NADP as acceptor | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
409 | Level5 | GO:0051425 | PTB domain binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
410 | Level5 | GO:0034189 | very\-low\-density lipoprotein binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
411 | Level5 | GO:0016642 | oxidoreductase activity\, acting on the CH\-NH2 group of donors\, disulfide as acceptor | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
412 | Level5 | GO:0032841 | calcitonin binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
413 | Level5 | GO:0016716 | oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, another compound as one donor\, and incorporation of one atom of oxygen | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
414 | Level5 | GO:0048407 | platelet\-derived growth factor binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
415 | Level5 | GO:0051538 | 3 iron\, 4 sulfur cluster binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
416 | Level5 | GO:0005061 | aryl hydrocarbon receptor nuclear translocator activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
417 | Level5 | GO:0050682 | AF\-2 domain binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
418 | Level5 | GO:0048187 | inhibin beta\-B binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
419 | Level5 | GO:0016652 | oxidoreductase activity\, acting on NADH or NADPH\, NAD or NADP as acceptor | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
420 | Level5 | GO:0008116 | prostaglandin\-I synthase activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
421 | Level5 | GO:0016899 | oxidoreductase activity\, acting on the CH\-OH group of donors\, oxygen as acceptor | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
422 | Level5 | GO:0001872 | zymosan binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
423 | Level5 | GO:0001849 | complement component C1q binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
424 | Level5 | GO:0008393 | fatty acid (omega\-1)\-hydroxylase activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
425 | Level5 | GO:0008160 | protein tyrosine phosphatase activator activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
426 | Level5 | GO:0042609 | CD4 receptor binding | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
427 | Level5 | GO:0015234 | thiamin transmembrane transporter activity | 1 | 1025 | 2 | 25252 | 1.13e-01 | 0.00 | 0.00 | 12.3 |
428 | Level4 | GO:0030742 | GTP\-dependent protein binding | 2 | 1024 | 13 | 25241 | 1.14e-01 | 0.00 | 0.00 | 3.8 |
429 | Level4 | GO:0004016 | adenylate cyclase activity | 2 | 1024 | 13 | 25241 | 1.14e-01 | 0.00 | 0.00 | 3.8 |
430 | Level4 | GO:0048306 | calcium\-dependent protein binding | 2 | 1024 | 13 | 25241 | 1.14e-01 | 0.00 | 0.00 | 3.8 |
431 | Level4 | GO:0015197 | peptide transporter activity | 2 | 1024 | 13 | 25241 | 1.14e-01 | 0.00 | 0.00 | 3.8 |
432 | Level4 | GO:0042166 | acetylcholine binding | 4 | 1022 | 45 | 25209 | 1.24e-01 | 0.00 | 0.00 | 2.2 |
433 | Level5 | GO:0050750 | low\-density lipoprotein receptor binding | 2 | 1024 | 14 | 25240 | 1.27e-01 | 0.00 | 0.00 | 3.5 |
434 | Level5 | GO:0015291 | secondary active transmembrane transporter activity | 20 | 1006 | 340 | 24914 | 1.29e-01 | 0.02 | 0.01 | 1.4 |
435 | Level4 | GO:0000149 | SNARE binding | 3 | 1023 | 30 | 25224 | 1.37e-01 | 0.00 | 0.00 | 2.5 |
436 | Level4 | GO:0050839 | cell adhesion molecule binding | 2 | 1024 | 15 | 25239 | 1.41e-01 | 0.00 | 0.00 | 3.3 |
437 | Level2 | GO:0045735 | nutrient reservoir activity | 6 | 1020 | 77 | 25177 | 1.42e-01 | 0.01 | 0.00 | 1.9 |
438 | Level5 | GO:0008188 | neuropeptide receptor activity | 10 | 1016 | 150 | 25104 | 1.45e-01 | 0.01 | 0.01 | 1.6 |
439 | Level4 | GO:0042923 | neuropeptide binding | 10 | 1016 | 151 | 25103 | 1.47e-01 | 0.01 | 0.01 | 1.6 |
440 | Level4 | GO:0030023 | extracellular matrix constituent conferring elasticity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
441 | Level4 | GO:0042030 | ATPase inhibitor activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
442 | Level4 | GO:0008368 | Gram\-negative bacterial binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
443 | Level4 | GO:0019211 | phosphatase activator activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
444 | Level5 | GO:0004462 | lactoylglutathione lyase activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
445 | Level5 | GO:0016649 | oxidoreductase activity\, acting on the CH\-NH group of donors\, quinone or similar compound as acceptor | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
446 | Level5 | GO:0004329 | formate\-tetrahydrofolate ligase activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
447 | Level5 | GO:0004075 | biotin carboxylase activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
448 | Level5 | GO:0034187 | apolipoprotein E binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
449 | Level5 | GO:0004802 | transketolase activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
450 | Level5 | GO:0043425 | bHLH transcription factor binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
451 | Level5 | GO:0016838 | carbon\-oxygen lyase activity\, acting on phosphates | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
452 | Level5 | GO:0004055 | argininosuccinate synthase activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
453 | Level5 | GO:0050220 | prostaglandin\-E synthase activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
454 | Level5 | GO:0048186 | inhibin beta\-A binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
455 | Level5 | GO:0030156 | benzodiazepine receptor binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
456 | Level5 | GO:0031014 | troponin T binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
457 | Level5 | GO:0019215 | intermediate filament binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
458 | Level5 | GO:0030226 | apolipoprotein receptor activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
459 | Level5 | GO:0004478 | methionine adenosyltransferase activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
460 | Level5 | GO:0005121 | Toll binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
461 | Level5 | GO:0000268 | peroxisome targeting sequence binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
462 | Level5 | GO:0005113 | patched binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
463 | Level5 | GO:0005076 | receptor signaling protein serine/threonine kinase signaling protein activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
464 | Level5 | GO:0016639 | oxidoreductase activity\, acting on the CH\-NH2 group of donors\, NAD or NADP as acceptor | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
465 | Level5 | GO:0030911 | TPR domain binding | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
466 | Level5 | GO:0004019 | adenylosuccinate synthase activity | 1 | 1025 | 3 | 25251 | 1.47e-01 | 0.00 | 0.00 | 8.2 |
467 | Level5 | GO:0016655 | oxidoreductase activity\, acting on NADH or NADPH\, quinone or similar compound as acceptor | 4 | 1022 | 49 | 25205 | 1.52e-01 | 0.00 | 0.00 | 2.0 |
468 | Level3 | GO:0019840 | isoprenoid binding | 2 | 1024 | 16 | 25238 | 1.55e-01 | 0.00 | 0.00 | 3.1 |
469 | Level4 | GO:0005501 | retinoid binding | 2 | 1024 | 16 | 25238 | 1.55e-01 | 0.00 | 0.00 | 3.1 |
470 | Level5 | GO:0016455 | RNA polymerase II transcription mediator activity | 2 | 1024 | 16 | 25238 | 1.55e-01 | 0.00 | 0.00 | 3.1 |
471 | Level5 | GO:0043130 | ubiquitin binding | 2 | 1024 | 16 | 25238 | 1.55e-01 | 0.00 | 0.00 | 3.1 |
472 | Level5 | GO:0016878 | acid\-thiol ligase activity | 2 | 1024 | 16 | 25238 | 1.55e-01 | 0.00 | 0.00 | 3.1 |
473 | Level5 | GO:0005548 | phospholipid transporter activity | 3 | 1023 | 32 | 25222 | 1.55e-01 | 0.00 | 0.00 | 2.3 |
474 | Level5 | GO:0016758 | transferase activity\, transferring hexosyl groups | 13 | 1013 | 212 | 25042 | 1.62e-01 | 0.01 | 0.01 | 1.5 |
475 | Level4 | GO:0031177 | phosphopantetheine binding | 2 | 1024 | 17 | 25237 | 1.69e-01 | 0.00 | 0.00 | 2.9 |
476 | Level5 | GO:0005275 | amine transmembrane transporter activity | 6 | 1020 | 86 | 25168 | 1.76e-01 | 0.01 | 0.00 | 1.7 |
477 | Level3 | GO:0046848 | hydroxyapatite binding | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
478 | Level3 | GO:0043498 | cell surface binding | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
479 | Level4 | GO:0004800 | thyroxine 5'\-deiodinase activity | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
480 | Level4 | GO:0016744 | transferase activity\, transferring aldehyde or ketonic groups | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
481 | Level4 | GO:0002039 | p53 binding | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
482 | Level5 | GO:0016595 | glutamate binding | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
483 | Level5 | GO:0016842 | amidine\-lyase activity | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
484 | Level5 | GO:0016654 | oxidoreductase activity\, acting on NADH or NADPH\, disulfide as acceptor | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
485 | Level5 | GO:0042608 | T cell receptor binding | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
486 | Level5 | GO:0030172 | troponin C binding | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
487 | Level5 | GO:0008035 | high\-density lipoprotein binding | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
488 | Level5 | GO:0016728 | oxidoreductase activity\, acting on CH or CH2 groups\, disulfide as acceptor | 1 | 1025 | 4 | 25250 | 1.81e-01 | 0.00 | 0.00 | 6.2 |
489 | Level4 | GO:0016757 | transferase activity\, transferring glycosyl groups | 17 | 1009 | 304 | 24950 | 1.91e-01 | 0.02 | 0.01 | 1.4 |
490 | Level5 | GO:0008194 | UDP\-glycosyltransferase activity | 9 | 1017 | 139 | 25115 | 1.94e-01 | 0.01 | 0.01 | 1.6 |
491 | Level3 | GO:0003735 | structural constituent of ribosome | 6 | 1020 | 259 | 24995 | 2.01e-01 | 0.01 | 0.01 | 0.6 |
492 | Level4 | GO:0051213 | dioxygenase activity | 5 | 1021 | 67 | 25187 | 2.07e-01 | 0.00 | 0.00 | 1.8 |
493 | Level4 | GO:0035240 | dopamine binding | 5 | 1021 | 67 | 25187 | 2.07e-01 | 0.00 | 0.00 | 1.8 |
494 | Level5 | GO:0016702 | oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen\, incorporation of two atoms of oxygen | 5 | 1021 | 67 | 25187 | 2.07e-01 | 0.00 | 0.00 | 1.8 |
495 | Level5 | GO:0048029 | monosaccharide binding | 2 | 1024 | 20 | 25234 | 2.11e-01 | 0.00 | 0.00 | 2.5 |
496 | Level5 | GO:0004176 | ATP\-dependent peptidase activity | 2 | 1024 | 20 | 25234 | 2.11e-01 | 0.00 | 0.00 | 2.5 |
497 | Level5 | GO:0004859 | phospholipase inhibitor activity | 2 | 1024 | 20 | 25234 | 2.11e-01 | 0.00 | 0.00 | 2.5 |
498 | Level4 | GO:0048038 | quinone binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
499 | Level4 | GO:0046977 | TAP binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
500 | Level4 | GO:0048184 | follistatin binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
501 | Level5 | GO:0046978 | TAP1 binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
502 | Level5 | GO:0046979 | TAP2 binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
503 | Level5 | GO:0030976 | thiamin pyrophosphate binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
504 | Level5 | GO:0017134 | fibroblast growth factor binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
505 | Level5 | GO:0042924 | neuromedin U binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
506 | Level5 | GO:0016743 | carboxyl\- or carbamoyltransferase activity | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
507 | Level5 | GO:0016841 | ammonia\-lyase activity | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
508 | Level5 | GO:0030971 | receptor tyrosine kinase binding | 1 | 1025 | 5 | 25249 | 2.13e-01 | 0.00 | 0.00 | 4.9 |
509 | Level5 | GO:0019001 | guanyl nucleotide binding | 23 | 1003 | 435 | 24819 | 2.22e-01 | 0.02 | 0.02 | 1.3 |
510 | Level4 | GO:0005085 | guanyl\-nucleotide exchange factor activity | 3 | 1023 | 159 | 25095 | 2.22e-01 | 0.00 | 0.01 | 0.5 |
511 | Level4 | GO:0005048 | signal sequence binding | 2 | 1024 | 21 | 25233 | 2.26e-01 | 0.00 | 0.00 | 2.3 |
512 | Level4 | GO:0055102 | lipase inhibitor activity | 2 | 1024 | 21 | 25233 | 2.26e-01 | 0.00 | 0.00 | 2.3 |
513 | Level5 | GO:0030159 | receptor signaling complex scaffold activity | 2 | 1024 | 22 | 25232 | 2.41e-01 | 0.00 | 0.00 | 2.2 |
514 | Level4 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor protein activity | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
515 | Level4 | GO:0043027 | caspase inhibitor activity | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
516 | Level4 | GO:0016018 | cyclosporin A binding | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
517 | Level4 | GO:0016944 | RNA polymerase II transcription elongation factor activity | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
518 | Level4 | GO:0008517 | folic acid transporter activity | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
519 | Level4 | GO:0005521 | lamin binding | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
520 | Level5 | GO:0016019 | peptidoglycan receptor activity | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
521 | Level5 | GO:0008494 | translation activator activity | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
522 | Level5 | GO:0016832 | aldehyde\-lyase activity | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
523 | Level5 | GO:0035197 | siRNA binding | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
524 | Level5 | GO:0008607 | phosphorylase kinase regulator activity | 1 | 1025 | 6 | 25248 | 2.43e-01 | 0.00 | 0.00 | 4.1 |
525 | Level5 | GO:0005088 | Ras guanyl\-nucleotide exchange factor activity | 1 | 1025 | 89 | 25165 | 2.69e-01 | 0.00 | 0.00 | 0.3 |
526 | Level4 | GO:0019209 | kinase activator activity | 2 | 1024 | 24 | 25230 | 2.70e-01 | 0.00 | 0.00 | 2.1 |
527 | Level4 | GO:0032947 | protein complex scaffold | 2 | 1024 | 24 | 25230 | 2.70e-01 | 0.00 | 0.00 | 2.1 |
528 | Level5 | GO:0003727 | single\-stranded RNA binding | 2 | 1024 | 24 | 25230 | 2.70e-01 | 0.00 | 0.00 | 2.1 |
529 | Level2 | GO:0042056 | chemoattractant activity | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
530 | Level3 | GO:0001882 | nucleoside binding | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
531 | Level4 | GO:0031405 | lipoic acid binding | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
532 | Level4 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
533 | Level4 | GO:0001848 | complement binding | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
534 | Level5 | GO:0004128 | cytochrome\-b5 reductase activity | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
535 | Level5 | GO:0004086 | carbamoyl\-phosphate synthase activity | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
536 | Level5 | GO:0016847 | 1\-aminocyclopropane\-1\-carboxylate synthase activity | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
537 | Level5 | GO:0043121 | neurotrophin binding | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
538 | Level5 | GO:0001786 | phosphatidylserine binding | 1 | 1025 | 7 | 25247 | 2.73e-01 | 0.00 | 0.00 | 3.5 |
539 | Level3 | GO:0051184 | cofactor transporter activity | 2 | 1024 | 25 | 25229 | 2.85e-01 | 0.00 | 0.00 | 2.0 |
540 | Level5 | GO:0015932 | nucleobase\, nucleoside\, nucleotide and nucleic acid transmembrane transporter activity | 2 | 1024 | 25 | 25229 | 2.85e-01 | 0.00 | 0.00 | 2.0 |
541 | Level5 | GO:0003729 | mRNA binding | 4 | 1022 | 54 | 25200 | 2.89e-01 | 0.00 | 0.00 | 1.8 |
542 | Level5 | GO:0016779 | nucleotidyltransferase activity | 8 | 1018 | 140 | 25114 | 2.91e-01 | 0.01 | 0.01 | 1.4 |
543 | Level4 | GO:0030674 | protein binding\, bridging | 6 | 1020 | 97 | 25157 | 3.00e-01 | 0.01 | 0.00 | 1.5 |
544 | Level3 | GO:0008907 | integrase activity | 1 | 1025 | 8 | 25246 | 3.01e-01 | 0.00 | 0.00 | 3.1 |
545 | Level5 | GO:0008503 | benzodiazepine receptor activity | 1 | 1025 | 8 | 25246 | 3.01e-01 | 0.00 | 0.00 | 3.1 |
546 | Level4 | GO:0003723 | RNA binding | 25 | 1001 | 770 | 24484 | 3.06e-01 | 0.02 | 0.03 | 0.8 |
547 | Level5 | GO:0005342 | organic acid transmembrane transporter activity | 9 | 1017 | 160 | 25094 | 3.16e-01 | 0.01 | 0.01 | 1.4 |
548 | Level4 | GO:0051018 | protein kinase A binding | 1 | 1025 | 9 | 25245 | 3.29e-01 | 0.00 | 0.00 | 2.7 |
549 | Level5 | GO:0046912 | transferase activity\, transferring acyl groups\, acyl groups converted into alkyl on transfer | 1 | 1025 | 9 | 25245 | 3.29e-01 | 0.00 | 0.00 | 2.7 |
550 | Level5 | GO:0016538 | cyclin\-dependent protein kinase regulator activity | 1 | 1025 | 9 | 25245 | 3.29e-01 | 0.00 | 0.00 | 2.7 |
551 | Level5 | GO:0008139 | nuclear localization sequence binding | 1 | 1025 | 9 | 25245 | 3.29e-01 | 0.00 | 0.00 | 2.7 |
552 | Level3 | GO:0003823 | antigen binding | 4 | 1022 | 63 | 25191 | 3.35e-01 | 0.00 | 0.00 | 1.6 |
553 | Level5 | GO:0004952 | dopamine receptor activity | 4 | 1022 | 66 | 25188 | 3.53e-01 | 0.00 | 0.00 | 1.5 |
554 | Level4 | GO:0048185 | activin binding | 1 | 1025 | 10 | 25244 | 3.55e-01 | 0.00 | 0.00 | 2.5 |
555 | Level5 | GO:0048019 | receptor antagonist activity | 1 | 1025 | 10 | 25244 | 3.55e-01 | 0.00 | 0.00 | 2.5 |
556 | Level5 | GO:0003706 | ligand\-regulated transcription factor activity | 1 | 1025 | 10 | 25244 | 3.55e-01 | 0.00 | 0.00 | 2.5 |
557 | Level5 | GO:0008238 | exopeptidase activity | 7 | 1019 | 122 | 25132 | 3.56e-01 | 0.01 | 0.00 | 1.4 |
558 | Level5 | GO:0004553 | hydrolase activity\, hydrolyzing O\-glycosyl compounds | 7 | 1019 | 122 | 25132 | 3.56e-01 | 0.01 | 0.00 | 1.4 |
559 | Level4 | GO:0043168 | anion binding | 1 | 1025 | 73 | 25181 | 3.72e-01 | 0.00 | 0.00 | 0.3 |
560 | Level5 | GO:0031404 | chloride ion binding | 1 | 1025 | 73 | 25181 | 3.72e-01 | 0.00 | 0.00 | 0.3 |
561 | Level3 | GO:0051183 | vitamin transporter activity | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
562 | Level4 | GO:0042834 | peptidoglycan binding | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
563 | Level4 | GO:0004000 | adenosine deaminase activity | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
564 | Level4 | GO:0005095 | GTPase inhibitor activity | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
565 | Level4 | GO:0016679 | oxidoreductase activity\, acting on diphenols and related substances as donors | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
566 | Level5 | GO:0008329 | pattern recognition receptor activity | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
567 | Level5 | GO:0045296 | cadherin binding | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
568 | Level5 | GO:0005112 | Notch binding | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
569 | Level5 | GO:0019841 | retinol binding | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
570 | Level5 | GO:0016681 | oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor | 1 | 1025 | 11 | 25243 | 3.80e-01 | 0.00 | 0.00 | 2.2 |
571 | Level3 | GO:0030695 | GTPase regulator activity | 13 | 1013 | 428 | 24826 | 3.84e-01 | 0.01 | 0.02 | 0.7 |
572 | Level4 | GO:0001653 | peptide receptor activity | 21 | 1005 | 431 | 24823 | 3.90e-01 | 0.02 | 0.02 | 1.2 |
573 | Level5 | GO:0008528 | peptide receptor activity\, G\-protein coupled | 21 | 1005 | 431 | 24823 | 3.90e-01 | 0.02 | 0.02 | 1.2 |
574 | Level5 | GO:0005544 | calcium\-dependent phospholipid binding | 2 | 1024 | 33 | 25221 | 3.99e-01 | 0.00 | 0.00 | 1.5 |
575 | Level5 | GO:0035091 | phosphoinositide binding | 5 | 1021 | 84 | 25170 | 4.01e-01 | 0.00 | 0.00 | 1.5 |
576 | Level4 | GO:0015232 | heme transporter activity | 1 | 1025 | 12 | 25242 | 4.04e-01 | 0.00 | 0.00 | 2.1 |
577 | Level4 | GO:0008013 | beta\-catenin binding | 1 | 1025 | 12 | 25242 | 4.04e-01 | 0.00 | 0.00 | 2.1 |
578 | Level5 | GO:0015645 | fatty\-acid ligase activity | 1 | 1025 | 12 | 25242 | 4.04e-01 | 0.00 | 0.00 | 2.1 |
579 | Level5 | GO:0031625 | ubiquitin protein ligase binding | 1 | 1025 | 12 | 25242 | 4.04e-01 | 0.00 | 0.00 | 2.1 |
580 | Level5 | GO:0016918 | retinal binding | 1 | 1025 | 12 | 25242 | 4.04e-01 | 0.00 | 0.00 | 2.1 |
581 | Level5 | GO:0003725 | double\-stranded RNA binding | 3 | 1023 | 43 | 25211 | 4.27e-01 | 0.00 | 0.00 | 1.7 |
582 | Level3 | GO:0003709 | RNA polymerase III transcription factor activity | 1 | 1025 | 13 | 25241 | 4.28e-01 | 0.00 | 0.00 | 1.9 |
583 | Level5 | GO:0051020 | GTPase binding | 5 | 1021 | 91 | 25163 | 4.28e-01 | 0.00 | 0.00 | 1.4 |
584 | Level5 | GO:0016790 | thiolester hydrolase activity | 5 | 1021 | 91 | 25163 | 4.28e-01 | 0.00 | 0.00 | 1.4 |
585 | Level5 | GO:0015464 | acetylcholine receptor activity | 3 | 1023 | 44 | 25210 | 4.31e-01 | 0.00 | 0.00 | 1.7 |
586 | Level5 | GO:0003954 | NADH dehydrogenase activity | 3 | 1023 | 44 | 25210 | 4.31e-01 | 0.00 | 0.00 | 1.7 |
587 | Level4 | GO:0005083 | small GTPase regulator activity | 8 | 1018 | 275 | 24979 | 4.40e-01 | 0.01 | 0.01 | 0.7 |
588 | Level5 | GO:0042826 | histone deacetylase binding | 1 | 1025 | 14 | 25240 | 4.50e-01 | 0.00 | 0.00 | 1.8 |
589 | Level4 | GO:0005070 | SH3/SH2 adaptor activity | 3 | 1023 | 49 | 25205 | 4.57e-01 | 0.00 | 0.00 | 1.5 |
590 | Level4 | GO:0042605 | peptide antigen binding | 1 | 1025 | 15 | 25239 | 4.71e-01 | 0.00 | 0.00 | 1.6 |
591 | Level5 | GO:0008301 | DNA bending activity | 1 | 1025 | 15 | 25239 | 4.71e-01 | 0.00 | 0.00 | 1.6 |
592 | Level5 | GO:0016813 | hydrolase activity\, acting on carbon\-nitrogen (but not peptide) bonds\, in linear amidines | 1 | 1025 | 15 | 25239 | 4.71e-01 | 0.00 | 0.00 | 1.6 |
593 | Level5 | GO:0030295 | protein kinase activator activity | 1 | 1025 | 16 | 25238 | 4.92e-01 | 0.00 | 0.00 | 1.5 |
594 | Level5 | GO:0016763 | transferase activity\, transferring pentosyl groups | 3 | 1023 | 56 | 25198 | 5.02e-01 | 0.00 | 0.00 | 1.3 |
595 | Level5 | GO:0016780 | phosphotransferase activity\, for other substituted phosphate groups | 1 | 1025 | 18 | 25236 | 5.31e-01 | 0.00 | 0.00 | 1.4 |
596 | Level3 | GO:0005212 | structural constituent of eye lens | 1 | 1025 | 19 | 25235 | 5.49e-01 | 0.00 | 0.00 | 1.3 |
597 | Level5 | GO:0008484 | sulfuric ester hydrolase activity | 1 | 1025 | 20 | 25234 | 5.67e-01 | 0.00 | 0.00 | 1.2 |
598 | Level4 | GO:0016875 | ligase activity\, forming carbon\-oxygen bonds | 4 | 1022 | 79 | 25175 | 5.68e-01 | 0.00 | 0.00 | 1.2 |
599 | Level5 | GO:0016876 | ligase activity\, forming aminoacyl\-tRNA and related compounds | 4 | 1022 | 79 | 25175 | 5.68e-01 | 0.00 | 0.00 | 1.2 |
600 | Level2 | GO:0003774 | motor activity | 9 | 1017 | 180 | 25074 | 5.68e-01 | 0.01 | 0.01 | 1.2 |
601 | Level3 | GO:0003711 | transcription elongation regulator activity | 1 | 1025 | 21 | 25233 | 5.84e-01 | 0.00 | 0.00 | 1.2 |
602 | Level5 | GO:0000049 | tRNA binding | 1 | 1025 | 22 | 25232 | 6.00e-01 | 0.00 | 0.00 | 1.1 |
603 | Level3 | GO:0003777 | microtubule motor activity | 5 | 1021 | 97 | 25157 | 6.02e-01 | 0.00 | 0.00 | 1.3 |
604 | Level5 | GO:0005099 | Ras GTPase activator activity | 5 | 1021 | 103 | 25151 | 6.16e-01 | 0.00 | 0.00 | 1.2 |
605 | Level5 | GO:0031420 | alkali metal ion binding | 12 | 1014 | 257 | 24997 | 6.33e-01 | 0.01 | 0.01 | 1.1 |
606 | Level4 | GO:0008135 | translation factor activity\, nucleic acid binding | 6 | 1020 | 131 | 25123 | 6.59e-01 | 0.01 | 0.01 | 1.1 |
607 | Level4 | GO:0003724 | RNA helicase activity | 2 | 1024 | 37 | 25217 | 6.65e-01 | 0.00 | 0.00 | 1.3 |
608 | Level4 | GO:0016229 | steroid dehydrogenase activity | 2 | 1024 | 37 | 25217 | 6.65e-01 | 0.00 | 0.00 | 1.3 |
609 | Level4 | GO:0016251 | general RNA polymerase II transcription factor activity | 2 | 1024 | 41 | 25213 | 6.85e-01 | 0.00 | 0.00 | 1.2 |
610 | Level4 | GO:0003678 | DNA helicase activity | 2 | 1024 | 48 | 25206 | 7.23e-01 | 0.00 | 0.00 | 1.0 |
611 | Level5 | GO:0003743 | translation initiation factor activity | 2 | 1024 | 77 | 25177 | 7.71e-01 | 0.00 | 0.00 | 0.6 |
612 | Level5 | GO:0015631 | tubulin binding | 4 | 1022 | 86 | 25168 | 7.81e-01 | 0.00 | 0.00 | 1.1 |
613 | Level4 | GO:0051082 | unfolded protein binding | 6 | 1020 | 141 | 25113 | 8.30e-01 | 0.01 | 0.01 | 1.0 |
614 | Level4 | GO:0008565 | protein transporter activity | 7 | 1019 | 161 | 25093 | 8.40e-01 | 0.01 | 0.01 | 1.1 |
615 | Level4 | GO:0005096 | GTPase activator activity | 9 | 1017 | 254 | 25000 | 8.72e-01 | 0.01 | 0.01 | 0.9 |
616 | Level2 | GO:0045182 | translation regulator activity | 6 | 1020 | 150 | 25104 | 1.00e+00 | 0.01 | 0.01 | 1.0 |
617 | Level3 | GO:0004386 | helicase activity | 6 | 1020 | 171 | 25083 | 1.00e+00 | 0.01 | 0.01 | 0.9 |
618 | Level3 | GO:0019208 | phosphatase regulator activity | 2 | 1024 | 62 | 25192 | 1.00e+00 | 0.00 | 0.00 | 0.8 |
619 | Level3 | GO:0019239 | deaminase activity | 1 | 1025 | 35 | 25219 | 1.00e+00 | 0.00 | 0.00 | 0.7 |
620 | Level3 | GO:0031202 | RNA splicing factor activity\, transesterification mechanism | 1 | 1025 | 27 | 25227 | 1.00e+00 | 0.00 | 0.00 | 0.9 |
621 | Level3 | GO:0005326 | neurotransmitter transporter activity | 1 | 1025 | 33 | 25221 | 1.00e+00 | 0.00 | 0.00 | 0.7 |
622 | Level4 | GO:0008026 | ATP\-dependent helicase activity | 4 | 1022 | 118 | 25136 | 1.00e+00 | 0.00 | 0.00 | 0.8 |
623 | Level4 | GO:0031072 | heat shock protein binding | 2 | 1024 | 65 | 25189 | 1.00e+00 | 0.00 | 0.00 | 0.8 |
624 | Level4 | GO:0019888 | protein phosphatase regulator activity | 2 | 1024 | 60 | 25194 | 1.00e+00 | 0.00 | 0.00 | 0.8 |
625 | Level4 | GO:0042895 | antibiotic transporter activity | 1 | 1025 | 29 | 25225 | 1.00e+00 | 0.00 | 0.00 | 0.8 |
626 | Level4 | GO:0015307 | drug\:hydrogen antiporter activity | 1 | 1025 | 28 | 25226 | 1.00e+00 | 0.00 | 0.00 | 0.9 |
627 | Level4 | GO:0005328 | neurotransmitter\:sodium symporter activity | 1 | 1025 | 29 | 25225 | 1.00e+00 | 0.00 | 0.00 | 0.8 |
628 | Level5 | GO:0016776 | phosphotransferase activity\, phosphate group as acceptor | 2 | 1024 | 51 | 25203 | 1.00e+00 | 0.00 | 0.00 | 1.0 |
629 | Level5 | GO:0016755 | transferase activity\, transferring amino\-acyl groups | 1 | 1025 | 25 | 25229 | 1.00e+00 | 0.00 | 0.00 | 1.0 |
630 | Level5 | GO:0008493 | tetracycline transporter activity | 1 | 1025 | 29 | 25225 | 1.00e+00 | 0.00 | 0.00 | 0.8 |
631 | Level5 | GO:0004004 | ATP\-dependent RNA helicase activity | 1 | 1025 | 24 | 25230 | 1.00e+00 | 0.00 | 0.00 | 1.0 |
632 | Level5 | GO:0016706 | oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, 2\-oxoglutarate as one donor\, and incorporation of one atom each of oxygen into both donors | 1 | 1025 | 28 | 25226 | 1.00e+00 | 0.00 | 0.00 | 0.9 |
633 | Level5 | GO:0008060 | ARF GTPase activator activity | 1 | 1025 | 32 | 25222 | 1.00e+00 | 0.00 | 0.00 | 0.8 |
634 | Level5 | GO:0004003 | ATP\-dependent DNA helicase activity | 1 | 1025 | 27 | 25227 | 1.00e+00 | 0.00 | 0.00 | 0.9 |
635 | Level5 | GO:0003746 | translation elongation factor activity | 1 | 1025 | 25 | 25229 | 1.00e+00 | 0.00 | 0.00 | 1.0 |
636 | Level5 | GO:0008601 | protein phosphatase type 2A regulator activity | 1 | 1025 | 25 | 25229 | 1.00e+00 | 0.00 | 0.00 | 1.0 |
637 | Level5 | GO:0008146 | sulfotransferase activity | 1 | 1025 | 49 | 25205 | 1.00e+00 | 0.00 | 0.00 | 0.5 |