SciMiner Mined Target Summary Page

Here are the targets (genes/proteins) that SciMiner has mined.

Rank	HUGO	Symbol	Target Name	#Occur	#Paper	Matched_Terms	MiMI	BG#1 paper	p-value	p-value (BH)	BG#2 paper	p-value	p-value (BH)	BG#3 paper	p-value	p-value (BH)
1	11179	SOD1	superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))	2479	368	superoxide dismutase | superoxide dismutase 1 | SOD-superoxide | Sod1 | SOD-1 | SOD1 | SOD-determination | SOD-supplemented | SOD-mimetics | SOD-deficient | SOD-mimetic | SOD-treated | SOD-induced | SODs | hSOD | SOD-like | SOD-mediated | SOD-inhibitable | SOD1-specific | SOD-transduced | ALS | SOD-sensitive | SOD-injected | SOD-dependent | SOD-exposed		31	2.98E-087	3.05E-084	38	1.98E-081	2.03E-078	38	1.98E-081	2.03E-078
2	1516	CAT	catalase	1424	241	catalase | CAT | CAT-reversible		22	4.12E-053	2.11E-050	30	7.66E-047	3.93E-044	30	7.66E-047	3.93E-044
3	14874	NOX5	NADPH oxidase, EF-hand calcium binding domain 5	1393	177	nadph oxidase | Nox5 | NOX5		9	9.01E-045	3.08E-042	12	1.39E-041	3.55E-039	14	8.10E-040	2.08E-037
4	6081	INS	insulin	4605	503	insulin | proinsulin | proinsulin-like | INS		201	2.31E-043	5.94E-041	193	5.70E-046	1.95E-043	205	6.63E-042	2.27E-039
5	12805	XDH	xanthine dehydrogenase	375	133	xanthine oxidase | xanthine dehydrogenase | xanthine oxidoreductase | XOR		7	7.16E-033	1.47E-030	9	5.65E-031	1.16E-028	10	4.30E-030	8.83E-028
6	9393	PRKCA	protein kinase C, alpha	491	194	protein kinase c | pkc alpha | protein kinase c alpha | PKCA | PKC-A | PRKCA | PKC-alpha | PKCI | PKC-alpha-dependent		46	4.17E-025	7.14E-023	40	3.74E-028	6.39E-026	44	5.18E-026	8.86E-024
7	7660	NCF1	neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)	602	72	p47 protein | neutrophil cytosolic factor 1 | NCF1 | P47- | p47phox-containing | Ncf1 | p47phox-dependent | p47phox-induced		1	5.15E-021	7.55E-019	4	6.79E-018	7.74E-016	4	6.79E-018	8.70E-016
8	7876	NOS3	nitric oxide synthase 3 (endothelial cell)	1993	115	endothelial nitric oxide synthase | eNOS-mediated | eNOS-generated | eNOS-associated | NOS-mediated | eNOS-expression | eNOS-knockout | eNOS-specific | eNOS-induced | NOS-3 | ecNOS | eNOS-dependent | NOS3 | eNOS-independent | eNOS-related | eNOS-containing | eNOS-derived | eNOS-driven | eNOS-deficient		16	1.26E-020	1.62E-018	20	2.66E-018	3.90E-016	17	5.16E-020	7.56E-018
9	11180	SOD2	superoxide dismutase 2, mitochondrial	817	85	mn sod | manganese superoxide dismutase | mn superoxide dismutase | superoxide dismutase 2 | SOD2- | MnSod | SOD-2 | Mn-SOD- | MnSOD-expressing | MnSOD-deficient | sod2 | Sod2 | MnSOD-transduced		5	1.81E-020	2.06E-018	8	6.02E-018	7.73E-016	9	3.29E-017	3.76E-015
10	2577	CYBA	cytochrome b-245, alpha polypeptide	436	69	p22 phox | p22phox | p22-phox | p22phox-mediated | p22phox-containing | CYBA		2	4.13E-019	4.24E-017	6	4.84E-015	4.97E-013	5	7.43E-016	6.93E-014
11	7873	NOS2A	nitric oxide synthase 2A (inducible, hepatocytes)	932	144	nitric oxide synthase | NOS-dependent | iNOS-positive | NOS-inhibitor | NOS-independent | Nos2 | iNOS-knockout | iNOS-expressing | iNOS-expression | iNOS-mediated | NOS2A | NOS2 | iNOS-dependent | iNOS-selective | iNOS-deficient | NOS-2		35	4.14E-018	3.86E-016	46	6.12E-014	5.23E-012	40	4.36E-016	4.47E-014
12	333	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	1997	131	angiotensin ii | ang ii | angiotensinogen | ang i | angiotensin i | Ang-II-dependent | Ang-II-induced | Agt | AngII | AngII-mediated | ANG | AGT | AngI | Ang-II-infused | AngII-like		32	2.08E-016	1.78E-014	46	2.20E-011	1.41E-009	51	5.87E-010	3.54E-008
13	381	AKR1B1	aldo-keto reductase family 1, member B1 (aldose reductase)	157	61	aldose reductase | AKR1B1 | ALR2		4	1.02E-014	8.03E-013	4	1.02E-014	9.50E-013	6	4.19E-013	3.58E-011
14	2578	CYBB	cytochrome b-245, beta polypeptide (chronic granulomatous disease)	463	49	gp91 phox | p91 phox | NOX2-Deficient | gp91phox-containing | CYBB | Nox2-containing | Nox-2 | gp-91-phox | NOX-2 | NOX2-deficient | Cybb | Nox2-Containing | nox2-dependent | CGD | Nox2-deficient | NOX2-containing | Nox2-derived		1	5.50E-014	4.03E-012	4	4.54E-011	2.59E-009	2	7.30E-013	5.76E-011
15	7872	NOS1	nitric oxide synthase 1 (neuronal)	878	82	neuronal nitric oxide synthase | nNOS-containing | NOS-dependent | NOS-1 | nNOS-independent | nNOS-positive | NOS-inhibitor | nNOS-deficient | nNOS-dependent | NOS-positive | NOS-independent | NOS-like | nNOS-mediated | NOS-immunoreactive | NOSs | NOS-inhibition | NOS-Mediated | NOS-specific | NOS-derived | nNOS-negative | nNOS-immunoreactive | NOS1-deficient | NOS-selective | NOS-knockout | nNOS-derived		13	7.18E-014	4.91E-012	17	5.03E-012	3.68E-010	19	6.80E-011	4.65E-009
16	7661	NCF2	neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)	205	50	chronic granulomatous disease | p67 phox | p67phox | p67-phox | NCF2		2	3.71E-013	2.38E-011	4	2.40E-011	1.45E-009	6	6.67E-010	3.80E-008
17	19986	CYCS	cytochrome c, somatic	308	81	cytochrome c		17	1.45E-011	8.72E-010	16	2.84E-012	2.24E-010	16	2.84E-012	2.08E-010
18	4827	HBB	hemoglobin, beta	442	101	beta globin | hemoglobin		31	2.46E-010	1.40E-008	27	8.56E-012	5.85E-010	32	3.45E-010	2.21E-008
19	4623	GSR	glutathione reductase	141	61	glutathione reductase		10	2.62E-010	1.41E-008	11	8.92E-010	4.82E-008	11	8.92E-010	4.82E-008
20	12517	UCP1	uncoupling protein 1 (mitochondrial, proton carrier)	325	38	uncoupling protein 1 | UCPs | UCP1 | UCP-1_amp_#x02013 | UCP1-expressing | UCP-1 | UCP1-overexpressing		3	8.05E-009	4.13E-007	4	4.41E-008	2.06E-006	5	1.98E-007	9.65E-006
21	7891	NOX4	NADPH oxidase 4	371	31	NOX-4 | Nox4-containing | Nox4-derived | Nox4-transfected | nox4 | Nox-4 | NOX4 | nox-4 | Renox | Nox4-treated		1	1.27E-008	6.20E-007	5	6.41E-006	2.27E-004	3	6.48E-007	2.66E-005
22	270	PARP1	poly (ADP-ribose) polymerase family, member 1	460	37	poly adp ribose synthetase | poly adp ribose polymerase | parp 1 | dna repair enzyme | poly adp ribose polymerase 1 | PARP | PARP-induced | PARP-1 | PARP-deficient | PARP-1_amp_#x02013 | PARPs | PARP-mediated		3	1.52E-008	7.08E-007	2	2.18E-009	1.12E-007	6	1.33E-006	5.25E-005
23	12518	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	434	34	uncoupling protein 2 | UCP2-mediated | UCP2-upregulated | UCP2-overexpressing | Ucp2-deficient | ucp2 | UCP2-deficient | UCP-2 | UCP2-regulated		2	1.56E-008	6.95E-007	3	1.00E-007	4.48E-006	4	4.98E-007	2.13E-005
24	4823	HBA1	hemoglobin, alpha 1	86	30	HB-A | HBA1 | HbA1 | HbA | HBA | Hba1		1	2.49E-008	1.07E-006	1	2.49E-008	1.22E-006	2	2.09E-007	9.30E-006
25	399	ALB	albumin	550	179	albumin | serum albumin		97	1.71E-007	7.00E-006	96	1.14E-007	4.87E-006	93	3.26E-008	1.67E-006
26	7889	NOX1	NADPH oxidase 1	262	30	mitogenic oxidase | gp91 2 | nadph oxidase 1 | NOX-derived | nox1 | NOX-mediated | NOX-1 | Nox1-derived | Mox1 | nox-1 | NOX1 | MOX-1 | Nox-1 | NOXs | Nox1-generated | NOX-knockout | NOX-dependent | Mox-1 | Nox1-containing		2	2.09E-007	8.23E-006	2	2.09E-007	8.56E-006	2	2.09E-007	9.72E-006
27	7794	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	792	90	nf kappa b | nuclear factor kappa b | nfkb p50 | NFKB1 | NF-kappaB-induced | NF-kappaB-controlled | NF-kB | NF-kappaB-dependent | p105 | NF-kappaB-mediated | NFkB | NF-kappaB-specific | NF-kappaB-activated		34	2.48E-007	9.42E-006	39	3.18E-006	1.21E-004	41	1.28E-005	4.53E-004
28	12680	VEGFA	vascular endothelial growth factor A	956	57	vascular endothelial growth factor | vascular permeability factor | vascular endothelial growth factor a | vegf a | VEGF-dependent | VEGFA | Vegf | Vegf-A | VEGF-stimulated | VEGF-neutralizing | VEGF-unrelated | VEGF-induced | VEGF-mediated | VEGF-A | VEGF-treated | VEGF-A-induced		19	7.03E-006	2.57E-004	18	5.16E-006	1.89E-004	23	1.41E-004	4.14E-003
29	11181	SOD3	superoxide dismutase 3, extracellular	411	18	extracellular superoxide dismutase | extracellular superoxide dismutase ec sod | ECSOD | SOD3 | EC-SOD		0	7.14E-006	2.52E-004	4	4.17E-003	8.07E-002	3	1.42E-003	3.39E-002
30	9958	REN	renin	117	51	renin		16	1.07E-005	3.64E-004	23	8.97E-004	2.19E-002	26	3.73E-003	7.22E-002
31	7218	MPO	myeloperoxidase	227	28	myeloperoxidase | MPO-amplified | MPO-dependent | MPO-deficient | MPO-induced | MPO-derived | MPO-catalyzed | MPO-mediated		4	1.71E-005	5.65E-004	12	1.57E-002	2.37E-001	9	2.37E-003	5.07E-002
32	11184	SORD	sorbitol dehydrogenase	32	15	sorbitol dehydrogenase | SDH		0	5.83E-005	1.81E-003	0	5.83E-005	1.93E-003	0	5.83E-005	1.81E-003
33	2202	COL4A1	collagen, type IV, alpha 1	126	15	collagen iv		0	5.83E-005	1.76E-003	1	4.98E-004	1.28E-002	0	5.83E-005	1.76E-003
34	11765	TGFA	transforming growth factor, alpha	62	46	transforming growth factor		15	7.15E-005	2.09E-003	20	1.60E-003	3.48E-002	13	9.50E-006	3.48E-004
35	2707	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	200	69	angiotensin converting enzyme | kininase ii | angiotensin i converting enzyme | ACE | ACE-independent | ACE-inhibitors		31	1.32E-004	3.75E-003	34	3.99E-004	1.11E-002	34	3.99E-004	1.11E-002
36	336	AGTR1	angiotensin II receptor, type 1	123	36	angiotensin ii receptor | AGTR1 | AT1-receptor | AT1R | Agtr1		10	1.35E-004	3.74E-003	14	2.34E-003	4.90E-002	9	5.61E-005	1.80E-003
37	4057	G6PD	glucose-6-phosphate dehydrogenase	59	19	glucose 6 phosphate dehydrogenase | glucose 6 phosphate dehydrogenase g6pd | G6PD		2	2.08E-004	5.62E-003	7	2.81E-002	3.65E-001	6	1.41E-002	2.10E-001
38	2295	CP	ceruloplasmin (ferroxidase)	22	13	ceruloplasmin | ferroxidase		0	2.36E-004	6.21E-003	3	2.08E-002	3.10E-001	3	2.08E-002	2.89E-001
39	7662	NCF4	neutrophil cytosolic factor 4, 40kDa	28	16	p40 | p40phox		1	2.62E-004	6.73E-003	0	2.90E-005	9.90E-004	0	2.90E-005	9.90E-004
40	7427	MT-CYB	mitochondrially encoded cytochrome b	47	15	cytochrome b		1	4.98E-004	1.25E-002	1	4.98E-004	1.31E-002	3	7.32E-003	1.29E-001
41	3062	DUOX1	dual oxidase 1	23	11	nicotinamide adenine dinucleotide phosphate oxidas | dual oxidase 1 | Duox1 | DUOX1		0	9.54E-004	2.22E-002	2	2.21E-002	2.94E-001	1	6.22E-003	1.12E-001
42	8583	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	948	37	plasminogen activator inhibitor | plasminogen activator inhibitor 1 | pai 1 | PAI-1-deficient | SERPINE1		14	1.06E-003	2.36E-002	14	1.06E-003	2.52E-002	9	3.42E-005	1.13E-003
43	25806	GSTCD	glutathione S-transferase, C-terminal domain containing	53	37	glutathione s transferase		14	1.06E-003	2.41E-002	20	3.10E-002	3.79E-001	16	4.97E-003	9.11E-002
44	2244	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	55	16	coenzyme q		2	1.26E-003	2.75E-002	4	1.15E-002	1.93E-001	2	1.26E-003	3.08E-002
45	9801	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	126	18	Rac-1 | rac1 | RAC1 | rac1-induced | Rac1		3	1.42E-003	3.04E-002	7	4.22E-002	4.33E-001	4	4.17E-003	7.78E-002
46	6834	MAOB	monoamine oxidase B	18	10	amine oxidase		0	1.92E-003	3.85E-002	2	3.81E-002	4.07E-001	2	3.81E-002	4.39E-001
47	12519	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	655	17	uncoupling protein 3 | UCP-3 | UCP3-ablated | UCP3-mediated | UCP3-induced | UCP3-transfected | UCP3-deficient		3	2.47E-003	4.70E-002	2	6.96E-004	1.74E-002	2	6.96E-004	1.78E-002
48	12663	VCAM1	vascular cell adhesion molecule 1	175	29	vascular cell adhesion molecule 1 | VCAM1 | Vcam1 | VCAM-1		10	3.12E-003	5.43E-002	10	3.12E-003	6.28E-002	9	1.52E-003	3.54E-002
49	391	AKT1	v-akt murine thymoma viral oncogene homolog 1	592	75	protein kinase b | pkb alpha | AKT-mediated | rac | Akt-1 | Rac-1-independent | Rac-regulated | Akt-regulated | Akt-independent | AKT-insensitive | AKT1 | PKB-dependent | PKB-independent | AKT-phosphorylated | Akt-signaling | Rac-1-expressing | Akt-Forkhead | Akt-kinase		43	3.24E-003	5.54E-002	42	2.27E-003	4.85E-002	43	3.24E-003	6.39E-002
50	6554	LEPR	leptin receptor	50	21	leptin receptor | LEPR | Lepr		6	5.65E-003	8.65E-002	8	2.33E-002	3.06E-001	4	5.01E-004	1.35E-002
51	3176	EDN1	endothelin 1	491	38	endothelin 1 | ET-1 | EDN1		17	5.85E-003	8.82E-002	21	3.40E-002	3.75E-001	14	1.05E-003	2.63E-002
52	2197	COL1A1	collagen, type I, alpha 1	634	84	collagen i | collagen-induced | collagen-specific		52	5.96E-003	8.73E-002	47	1.13E-003	2.63E-002	54	1.07E-002	1.68E-001
53	10618	CCL2	chemokine (C-C motif) ligand 2	291	38	monocyte chemotactic protein 1 | monocyte chemoattractant protein 1 | mcp 1 | Ccl2 | MCP-1		19	1.51E-002	1.96E-001	16	2.38E-003	4.89E-002	13	3.55E-004	1.01E-002

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