HUGO ID Detailed Result 613

HUGO ID Detailed Result 613

HUGO ID	613
Symbol	APOE
Name	apolipoprotein E
#Occurrence	32
#Paper	11

PMID	Match String	Actual String	Score	Flanking text
11173059	APOE	ApoE	2.4	the analysis of allele polymorphism of the apolipoprotein E (ApoE) ApoE gene
11173059	APOE	ApoE	2.4	The ApoE gene maps on chromosome 19q12-q13 and contains three common coding
11173059	APOE	ApoE	2.4	ApoE 4 is neither necessary nor sufficient to cause Alzheimer disease
11173059	APOE	ApoE	2.4	However the increased risk of developing Alzheimer disease provided by ApoE 4 may be due to its higher affinity for _amp_#x3b2
11173059	APOE	ApoE	2.4	at position _amp_#x2212 491 in the 5_amp_#x2032 -promoter region of ApoE has been reported to be associated with an increased risk
11173059	APOE	ApoE	2.4	_amp_#x2212 491 polymorphism appears to be independent of that of ApoE 4 and is associated with a rise in ApoE plasma
11173059	APOE	ApoE	2.4	of ApoE 4 and is associated with a rise in ApoE plasma levels ( Laws et al. 1999
11173059	APOE	ApoE	2.4	of other ligands including _amp_#x3b2 -amyloid protein amyloid precursor protein ApoE and cholesterol ( Rosenberg 2000 -2-Macroglobulin also binds to _amp_#x3b2
11173059	APOE	ApoE	2.4	and is believed to contribute to the clearance of ApoE/_amp_#x3b2;-amyloid ApoE _amp_#x3b2 -amyloid protein and -2-macroglobulin/_amp_#x3b2;-amyloid -2-macroglobulin _amp_#x3b2 -amyloid protein complexes
11173059	APOE	ApoE-containing	1.3	density lipoprotein (VLDL) VLDL receptor functions as a receptor for ApoE-containing lipoproteins and for this reason it has been hypothesized to
11173059	APOE	ApoE	2.4	of Alzheimer disease (i.e., i.e. siblings of Alzheimer disease patients ApoE 4 carriers and bearing specific polymorphisms of cytokine genes
11173059	APOE	ApoE	2.4	risk of Alzheimer disease ( Li and Li whereas the ApoE genotype seems to affect the response to acetylcholinesterase inhibitors (
14739060	APOE	APOE	0.0	a complex interaction among multiple predisposing genes such as variant APOE the gene for _amp_#x3b1 2 -macrogobulin and perhaps the gene
14739060	APOE	APOE	0.0	proteins (_amp_#x3b2;-amyloid, _amp_#x3b2 -amyloid especially its toxic form A_amp_#x3b2 42 APOE 43 hyperphosphorylated tau ubiquitin presenilin 1_amp_#xa0 and 2 with an
15210305	APOE	ApoE	1.3	Apolipoprotein E (ApoE) ApoE and (to to a lesser extent Apo D gene expression
16766086	APOE	ApoE	0.0	Importantly the efficacy of drug treatment was related to ApoE genotype
17569578	APOE	ApoE	0.0	the differential effects of rosiglitazone in individuals depending on their ApoE genotype is unexplained
17597167	APOE	apoE	0.3	so called Swedish mutation 31 and gliosis in apolipoprotein (apoE) apoE knock-out mice 32
18513389	APOE	APOE	1.3	C T 3175 C/G, C G 3206 T/G, T G APOE cys112arg arg158cys ADRB3 trp64arg PPAR_amp_#x003b3 pro12ala LIPC 480C/T, 480C T
18513389	APOE	APOE	1.3	independently selected by the five TWIST procedures apolipoprotein E (APOE) APOE (chromosome chromosome 19q13.2 arg158cys hepatic lipase (LIPC) LIPC (chromosome chromosome
18513389	APOE	ApoE	1.3	Indeed ApoE arg158cys was selected by all the five TWISTs while the
18513389	APOE	ApoE	1.3	arg158cys was selected by all the five TWISTs while the ApoE cys112arg was selected only once
18513389	APOE	ApoE	1.3	gene variations confirm some of the already known results (ApoE ApoE and PON for example and identify new gene/genetic gene genetic
11173059	apolipoprotein e	apolipoprotein e	1.0	at present the most important genetic information in patients with late onset alzheimer disease comes from the analysis of allele polymorphism of the apolipoprotein e apoe gene.
15210305	apolipoprotein e	apolipoprotein e	1.0	no conclusive data have emerged from the analysis of potential risk factors in als such as the neurofilament heavy subunit [ 25 ] the apolipoprotein e allele 4 [ 71 ] the gene survival motor neuron smn and neuronal apoptosis inhibitory protein naip [ 79 ].
15210305	apolipoprotein e	apolipoprotein e	1.0	apolipoprotein e apoe and to a lesser extent apo d gene expression are induced up to fivefold at 120 days of age.
16753239	apolipoprotein e	apolipoprotein e	1.0	the ppar _amp_#x3b1; agonist fenofibrate reduced the susceptibility of apolipoprotein e deficient mice to stroke.
18414597	apolipoprotein e	apolipoprotein e	1.0	apolipoprotein e is the principal cholesterol carrier protein in the brain and the gene encoding the variant apolipoprotein e4 is a significant risk factor for alzheimer's disease.
18464925	apolipoprotein e	apolipoprotein e	1.0	in a second recent trial the improvement in cognition after 6 months of rosiglitazone treatment was significant only in ad patients who did not have the _amp_#x003b5; 4 allele of the apolipoprotein e [ 92 ] a genotype associate with a higher risk to develop ad.
18513389	apolipoprotein e	apolipoprotein e	1.0	this latter approach allowed the identification of seven genetic variants essential to differentiate cases from controls: apolipoprotein e arg158cys; hepatic lipase 480 c/t; endothelial nitric oxide synthase 690 c/t and glu298asp; vitamin k dependent coagulation factor seven arg353glu glycoprotein ia/iia 873 g/a and e selectin ser128arg
18513389	apolipoprotein e	apolipoprotein e	1.0	genetic variants selected by the five twist procedures seven genetic variants were always independently selected by the five twist procedures: apolipoprotein e apoe chromosome 19q13.2 arg158cys; hepatic lipase lipc chromosome 15q21 23 480 c/t; endothelial nitric oxide synthase nos3 chromosome 7q36 690 c/t and glu298asp; vitamin k dependent coagulation facto
18751914	apolipoprotein e	apolipoprotein e	1.0	apolipoprotein e is the principal cholesterol carrier protein in the brain and the gene encoding the variant apolipoprotein e4 is a significant risk factor for alzheimer's disease.