HUGO ID Detailed Result 2160


HUGO ID 2160
Symbol CNR2
Name cannabinoid receptor 2 (macrophage)
#Occurrence 7
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
17241118CB2CB20.9The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model 
17241118CB2CB20.9cannabinoid receptor 1 (CB1) CB1 and cannabinoid receptor 2 (CB2), CB2 and delay the progression of neuroinflammatory diseases 
17241118CB2CB20.9Additionally CB2 receptors which normally exist primarily in the periphery are dramatically 
17241118CB2CB20.9We demonstrate that mRNA receptor binding and function of CB2 but not CB1 receptors are dramatically and selectively up-regulated in 
17241118CB2CB20.9More importantly daily injections of the selective CB2 agonist AM-1241 initiated at symptom onset increase the survival interval 
17241118CB2CB20.9Therefore CB2 agonists may slow motor neuron degeneration and preserve motor function 
17241118cannabinoid receptor 2cannabinoid receptor 21.0cannabinoids produce anti inflammatory actions via cannabinoid receptor 1 cb1 and cannabinoid receptor 2 cb2 and delay the progression of neuroinflammatory diseases.