HUGO ID Detailed Result 11180


HUGO ID 11180
Symbol SOD2
Name superoxide dismutase 2, mitochondrial
#Occurrence 17
#Paper 4

 


PMID Match String Actual String Score Flanking text Edited by Edit
8605177MnSODMnSOD1.9Human manganese superoxide dismutase (MnSOD) MnSOD is a homotetrameric enzyme which protects mitochondria against oxygen-mediated free 
8605177MnSODMnSOD1.9A crystallographic structure of the naturally occurring polymorphic variant Ile58Thr MnSOD reveals that the helical hairpin mutation Thr58 causes two packing 
8605177MnSODMnSOD1.9Ile58Thr MnSOD is primarily dimeric in solution and is significantly less thermostable 
8605177MnSODMnSOD1.9Consequently this mutant MnSOD is compromised at normal body temperatures thermal inactivation predicted from 
8605177MnSODMnSOD1.9at 41 degrees C compared with 3.1 years for native MnSOD 
8605177MnSODMnSOD1.93 h has no effect on the activity of native MnSOD but completely inactivates mutant MnSOD 
8605177MnSODMnSOD1.9on the activity of native MnSOD but completely inactivates mutant MnSOD 
8605177MnSODMnSOD1.9Rapid inactivation of Ile58Thr MnSOD at the elevated temperatures associated with fever and inflammation could 
14739060MnSODMnSOD1.8Tat protein decreases GSH and down regulate MnSOD gene expression leading to oxidative stress 16 
17191135Mn-SODMn-SOD1.9genes such as heme oxygenase thioredoxin and detoxificant enzymes (Mn-SOD, Mn-SOD glutathione S-transferase NADPH quinone reductase cytokine immunoreceptors and growth factors 
17191135Mn-SODMn-SOD1.9of stress-inducible genes 107 -124 such as HO-1 G-glutamylcysteine synthetase Mn-SOD and glutathione S-transferase 
18513389SOD2SOD20.9CYP2D6 apurinic apyrimidinic endonuclease (APEX), APEX mitochondrial manganese superoxide dismutase SOD2 monoamine oxidase allele B and paraoxonases have been reported in 
8605177manganese superoxide dismutasemanganese superoxide dismutase1.0human mitochondrial manganese superoxide dismutase polymorphic variant ile58thr reduces activity by destabilizing the tetrameric interface.  
8605177manganese superoxide dismutasemanganese superoxide dismutase1.0human manganese superoxide dismutase mnsod is a homotetrameric enzyme which protects mitochondria against oxygen mediated free radical damage.  
17191135mn sodmn sod1.0in eukaryotes typical examples are genes such as heme oxygenase thioredoxin and detoxificant enzymes mn sod glutathione s transferase nadph: quinone reductase cytokine immunoreceptors and growth factors.  
17191135mn sodmn sod1.0e alone in unstressed conditions by promoting acetylation of dna binding proteins may modulate are mediated expression of stress inducible genes [ 107 124 ] such as ho 1 g glutamylcysteine synthetase mn sod and glutathione s transferase.  
18513389manganese superoxide dismutasemanganese superoxide dismutase1.0filaments apolipoprotein epsilon 4 genotype excitotoxicity genes ciliary neurotrophic factor ctnf cytochrome p450 debrisoquine hydroxylase cyp2d6 apurinic apyrimidinic endonuclease apex mitochondrial manganese superoxide dismutase sod2 monoamine oxidase allele b and paraoxonases have been reported in different studies partly with contradictory results [ 2 4 7 9 ].