Current Target Information
| HUGO ID | 391 |
|---|---|
| Symbol | AKT1 |
| Name | v-akt murine thymoma viral oncogene homolog 1 |
| #Occurrence | 72 |
| #Paper | 8 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 11679167 | Oxidative stress and signal transduction in Saccharomyces cerevisiae: insights into ageing, apoptosis and diseases. | 44 | | Mol Aspects Med |
| 17496232 | Mitochondrial nitric oxide in the signaling of cell integrated responses. | 43 | | Am J Physiol Cell Physiol |
| 17105868 | Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis. | 22 | | Mol Pharmacol |
| 12654515 | VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death. | 17 | | Brain Res Mol Brain Res |
| 18219386 | Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1. | 16 | | J Clin Invest |
| 16877542 | The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. | 13 | | Proc Natl Acad Sci U S A |
| 17956327 | Respiratory plasticity following intermittent hypoxia: roles of protein phosphatases and reactive oxygen species. | 13 | | Biochem Soc Trans |
| 18422522 | Endothelial nitric oxide synthase overexpression by neuronal cells in neurodegeneration: a link between inflammation and neuroprotection. | 5 | | J Neurochem |