Current Target Information
| HUGO ID | 11180 |
|---|---|
| Symbol | SOD2 |
| Name | superoxide dismutase 2, mitochondrial |
| #Occurrence | 100 |
| #Paper | 19 |
| PMID | TITLE | # of Targets | Links | Journal |
|---|---|---|---|---|
| 17191135 | Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes. | 60 | | Neurochem Res |
| 15896810 | Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia. | 55 | | J Neurol Sci |
| 11679167 | Oxidative stress and signal transduction in Saccharomyces cerevisiae: insights into ageing, apoptosis and diseases. | 44 | | Mol Aspects Med |
| 17496232 | Mitochondrial nitric oxide in the signaling of cell integrated responses. | 43 | | Am J Physiol Cell Physiol |
| 17174478 | Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair. | 42 | | Neuroscience |
| 14739060 | Neurodegenerative diseases and oxidative stress. | 33 | | Biomed Pharmacother |
| 11050436 | Mitochondria, oxygen free radicals, disease and ageing. | 24 | | Trends Biochem Sci |
| 16227974 | Radical medicine: treating ageing to cure disease. | 23 | | Nat Rev Mol Cell Biol |
| 10742195 | Metals and neuroscience. | 20 | | Curr Opin Chem Biol |
| 14648077 | Histological evidence of redox system breakdown caused by superoxide dismutase 1 (SOD1) aggregation is common to SOD1-mutated motor neurons in humans and animal models. | 17 | | Acta Neuropathol |
| 10671549 | Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells. | 14 | | J Biol Chem |
| 11978481 | Oxidatively modified proteins in aging and disease. | 11 | | Free Radic Biol Med |
| 17099894 | Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. | 10 | | J Comp Neurol |
| 12392777 | A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes. | 6 | | Neurobiol Aging |
| 10930589 | Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1. | 5 | | J Neurol Sci |
| 15850589 | Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells. | 5 | | J Neurol Sci |
| 11905995 | Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival. | 4 | | J Neurochem |
| 9462746 | A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase. | 2 | | Nat Genet |
| 11328670 | Invited review: manganese superoxide dismutase in disease. | 1 | | Free Radic Res |