HUGO ID Detailed Result 9509


HUGO ID 9509
Symbol PSEN2
Name presenilin 2 (Alzheimer disease 4)
#Occurrence 9
#Paper 3

 


PMID Match String Actual String Score Flanking text Edited by Edit
10643818PS2PS22.4Presenilins (PS1 PS1 and PS2 contribute to the regulation of apoptosis with the 
10643818PS2PS22.4Presenilins (PS1 PS1 and PS2 contribute to the regulation of apoptosis with the wild-type of 
10643818STM2STM23.2the regulation of apoptosis with the wild-type of Alzheimer's gene STM2 (PS2) PS2 exerting anti-apoptotic effects 16 
10643818PS2PS22.4of apoptosis with the wild-type of Alzheimer's gene STM2 (PS2) PS2 exerting anti-apoptotic effects 16 
14739060PSEN2PSEN20.9well as presenilin 1 (PSEN1) PSEN1 and presenilin 2 (PSEN2) PSEN2 
10643818presenilin 2presenilin 21.0known genetic risk factors for familial alzheimer's disease have been localized to the amyloid precursor protein apolipoprotein e presenilin 1 and presenilin 2 genes.  
10643818presenilin 2presenilin 21.0during apoptosis they may be cleaved distal to their normal cleavage sites and a mutation in presenilin 2 that is related to familial alzheimer's disease favors this alternative cleavage which may either directly enhance apoptosis or diminish the apoptosis regulating function of the wild type fragments [ 
10742195presenilin 2presenilin 21.0familial ad linked mutations of amyloid precursor protein app presenilin 1 and presenilin 2 increase both cerebral a_amp_#x3b2; burden and a_amp_#x3b2;1 42 production underscoring the role that a_amp_#x3b2; metabolism plays in ad pathogenesis see [ 10 ] .  
14739060presenilin 2presenilin 21.0in familial forms missense mutation have been identified for gene encoding _amp_#x3b2; amyloid precursor protein as well as presenilin 1 psen1 and presenilin 2 psen2 .