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| 17174478 | NER | NER | 1.3 | damage verification by XPB promotes unwinding of damaged dsDNA for NER | |  |
| 17174478 | NER | NER | 1.3 | mismatch repair MRN Mre11/Rad50/Nbs1 Mre11 Rad50 Nbs1 mtDNA mitochondrial DNA NER nucleotide excision repair NO nitric oxide e i or nNOS | | |
| 17174478 | NER | NER | 1.3 | Nucleotide excision repair (NER) NER differs from BER by responding to DNA helix distorting damage | | |
| 17174478 | NER | NER | 1.3 | Evidence for NER in the brain also includes studies on cerebellar extracts ( | | |
| 17174478 | NER | NER | 1.3 | 1998 and also a few rare hereditary diseases in known NER genes that cause marked neurological pathology which are discussed later | | |
| 17174478 | NER | NER | 1.3 | NER and the XPB helicase | | |
| 17174478 | NER | NER | 1.3 | NER functions to restore short segments of nucleotides containing DNA helix | | |
| 17174478 | NER | NER | 1.3 | generated by ionizing radiation can produce DNA lesions that require NER for repair ( Satoh et al. 1993 | | |
| 17174478 | NER | NER | 1.3 | NER is a particularly versatile DNA repair system that is capable | | |
| 17174478 | NER | NER | 1.3 | Hereditary mutations in NER genes clearly demonstrate that the inherited DNA repair potential has | | |
| 17174478 | NER | NER | 1.3 | Moreover much of our understanding of NER has been derived from studies on cells from individuals with | | |
| 17174478 | NER | NER | 1.3 | has been derived from studies on cells from individuals with NER defects that present clinical phenotypes | | |
| 17174478 | NER | NER | 1.3 | to these transcriptional functions XPB also plays a role in NER | | |
| 17174478 | NER | NER | 1.3 | of how XPB and TFIIH function in both transcription and NER ( Coin et al. 2004 Coin et al. 2006 Fan | | |
| 17174478 | NER | NER | 1.3 | in the DNA typically caused by the broad spectrum of NER lesions | | |
| 17174478 | NER | NER | 1.3 | is located and linked to initiation of DNA unwinding during NER steps by XPB/TFIIH XPB TFIIH | | |
| 17174478 | NER | NER | 1.3 | NER and the XPB helicase | | |
| 17174478 | NER | NER | 1.3 | hydrolysis drives XPB to move along the duplex DNA during NER | | |
| 17174478 | NER | NER-specific | 0.3 | for this action whereas the domain reorientation described above is NER-specific and only occurs upon the interactions of the DRD with | | |
| 17174478 | NER | NER | 1.3 | NER and the XPB helicase | | |
| 17174478 | NER | NER | 1.3 | of human XPB was reported to regulate TFIIH activity in NER reactions ( Coin et al. 2004 | | |