HUGO ID Detailed Result 7211


HUGO ID 7211
Symbol MPG
Name N-methylpurine-DNA glycosylase
#Occurrence 8
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
9172131MPGMPG1.1to the human BER protein N -methylpurine DNA glycosylase (MPG) MPG and purified human MPG (positive positive control (both both provided 
9172131MPGMPG1.1protein N -methylpurine DNA glycosylase (MPG) MPG and purified human MPG (positive positive control (both both provided by Dr Sankar Mitra 
9172131MPGMPG1.1In contrast to APE levels cortical MPG levels in ALS subjects were not significantly different ( p 
9172131MPGMPG1.1removed by a DNA glycosylase (e.g e.g formamidopyrimidine DNA glycosylase MPG 20 21 and the resulting apurinic site repaired by APE 
9172131MPGMPG1.1The lack of a similar reduction in the BER protein MPG in ALS brain tissue suggests a selective abnormality in APE 
9172131n-methylpurine-dna glycosylasen methylpurine dna glycosylase1.0dna base excision repair ber is considered to be the predominant pathway for repair of oxidative dna damage. 9 the damaged base is removed by a glycosylase e.g formamidopyrimidine or n methylpurine dna glycosylase and the resulting abasic site is repaired by apurinic/apyrimidinic endonuclease ape .  
9172131n-methylpurine-dna glycosylasen methylpurine dna glycosylase1.0for comparison protein extracts 50 microg from several control n _amp_#61; 4 and als n _amp_#61; 3 subjects were analyzed by western blotting using a monoclonal antibody to the human ber protein n methylpurine dna glycosylase mpg and purified human mpg positive control both provided by dr sankar mitra utmb galveston tx .  
9172131n-methylpurine-dna glycosylase, mpgn methylpurine dna glycosylase mpg1.0for comparison protein extracts 50 microg from several control n _amp_#61; 4 and als n _amp_#61; 3 subjects were analyzed by western blotting using a monoclonal antibody to the human ber protein n methylpurine dna glycosylase mpg and purified human mpg positive control both provided by dr sankar mitra utmb galveston tx .