HUGO ID Detailed Result 6893

PMID	Match String	Actual String	Score	Flanking text	Edited by	Edit
10742195	tau	tau	0.3	many of the other neuropathological features of AD including intraneuronal tau abnormalities and neuronal loss 23 as well as signs of
11978481	tau	tau	2.7	aggregates which are largely made up of the microtubule-associated protein tau
12663085	tau	tau	0.9	Inclusion bodies and intracellular deposits associated with tau are implicated in AD and other neurodegenerative diseases
12663085	tau	tau	0.9	The glycation of tau has also been extensively studied with regard to AD 49
12663085	tau	tau	0.9	probed in soluble and insoluble PHF (paired paired helical filaments -tau from AD brains using anti-CML antibody
12663085	tau	tau	0.9	The results demonstrated that tau becomes glycated in PHF-tau and that the glycation may play
12663085	tau	tau	0.9	Glycated tau exhibited a loss of capacity in the promotion of microtubule
12663085	tau	tau	0.9	it was speculated that reactive oxygen species were produced by tau modified with AGE leading to the induction of HO-1
12663085	tau	tau	0.9	In vitro glycation of A_amp_#x3b2 tau and apoprotein E (apoE), apoE and their effects were investigated
12663085	tau	tau	0.9	In addition to hyperphosphorylation the glycation of tau leads to the formation of paired helical filaments in AD
12663085	tau	tau	0.9	AGE-modified tau produced reactive oxygen species in cultured cells and also caused
12893007	tau	tau	2.2	abnormal form of normally occurring microtubule-associated protein (MAP), MAP termed tau
12893007	tau	tau	2.2	Normal tau proteins are microtubule binding proteins predominantly axonal that stabilize the
12893007	tau	tau	2.2	In normal brain tau is phosphorylated but the phosphate groups are in postmortal tissue
12893007	tau	tau	2.2	In contrast tau protein in PHF is relatively resistant to postmortem dephosphorylation ([
12893007	tau	tau	2.2	In AD phosphorylation of tau on aberrant site could result in a protein that does
12893007	tau	tau	2.2	HNE is toxic for P19 cells causing cross-linking of tau into high molecular weight substances that are conjugated with ubiquitin
12893007	tau	tau	2.2	preferentially reacts with lysine residues that are prominent components of tau ( Uchida et al and are present in NFT and
14648077	tau	tau	0.8	been observed for normal cytosolic constitutive proteins including tubulin and tau protein as well as neuron-specific constitutive proteins containing phosphorylated neurofilament
14660707	tau	tau	0.3	2 transients was assessed by determining the recovery time constant tau (_amp_#x003c4;) _amp_#x003c4 after fitting with a single-exponential function
14739060	tau	tau	1.9	gene for _amp_#x3b1 2 -macrogobulin and perhaps the gene for tau protein and other factors including environmental contributions and occurrence by
14739060	tau	tau	1.9	tangles and senile plaques are both aggregation of proteins microtubular tau protein for the former accumulation of several aggregated proteins (_amp_#x3b2;-amyloid,
14739060	tau	tau	1.9	-amyloid especially its toxic form A_amp_#x3b2 42 APOE 43 hyperphosphorylated tau ubiquitin presenilin 1_amp_#xa0 and 2 with an inflammatory reaction around
16046141	tau	tau	0.3	(NeuN, NeuN class III _amp_#x3b2 -tubulin choline acetyltransferase PSD95 and tau Cozzolino et al. 2004
17191135	tau	tau	1.8	Binding of phosphorylated tau to Hsp70 implies that the complex may be a substrate
17191135	tau	tau	1.8	Together with Hsp70 CHIP can regulate tau ubiquitination and degradation in a cell culture system 87
17191135	tau	tau	1.8	in spinal cord which was the most prominent region for tau inclusions and neuronal loss
17191135	tau	tau	1.8	addition Takeda et al explored the relationship between HO-1 and tau protein this latter being the major component of intraneuronal neurofibrillary
17191135	tau	tau	1.8	of this enzyme was increased and conversely the level of tau protein was significantly decreased when compared with antisense HO-1 or
17191135	tau	tau	1.8	The suppression of tau protein expression was almost completely counteracted by zinc-deuteroporphyrin a specific
11978481	microtubule-associated protein tau	microtubule associated protein tau	1.0	neurofibrillary tangles are protein aggregates which are largely made up of the microtubule associated protein tau.
12893007	tau protein	tau protein	1.0	in contrast tau protein in phf is relatively resistant to postmortem dephosphorylation [ cooper et al ] .
14648077	tau protein	tau protein	1.0	such sequestration into lbhis has also been observed for normal cytosolic constitutive proteins including tubulin and tau protein as well as neuron specific constitutive proteins containing phosphorylated neurofilament proteins nfp nonphosphorylated nfp synaptophysin and neuron specific enolase [ 13 17 18 ]; this results in par
14739060	tau protein	tau protein	1.0	the sporadic forms are thought to result from a complex interaction among multiple predisposing genes such as variant apoe the gene for _amp_#x3b1; 2 macrogobulin and perhaps the gene for tau protein and other factors including environmental contributions and occurrence by chance [ 45 and 58 ].
14739060	tau protein	tau protein	1.0	the neuropathological hallmarks neurofibrillary tangles and senile plaques are both aggregation of proteins: microtubular tau protein for the former accumulation of several aggregated proteins _amp_#x3b2; amyloid especially its toxic form a_amp_#x3b2; 42 apoe [ 43 ] hyperphosphorylated tau ubiquitin presenilin 1_amp_#xa0;and 2 with
17191135	tau protein	tau protein	1.0	in addition takeda et al. explored the relationship between ho 1 and tau protein this latter being the major component of intraneuronal neurofibrillary tangles in ad [ 93 ].
17191135	tau protein	tau protein	1.0	in transfected neuroblastoma cells overexpressing ho 1 the activity of this enzyme was increased and conversely the level of tau protein was significantly decreased when compared with antisense ho 1 or vector transfected cells [ 93 ].
17191135	tau protein	tau protein	1.0	the suppression of tau protein expression was almost completely counteracted by zinc deuteroporphyrin a specific inhibitor of ho activity [ 93 ].