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| 11978481 | glutamine synthetase | glutamine synthetase | 1.0 | prior studies showed that glutamine synthetase and creatine kinase are particularly vulnerable to oxidative damage [ 12 and 20 ]. | |  |
| 11978481 | glutamine synthetase | glutamine synthetase | 1.0 | nitration of tyrosine residues in glutamine synthetase by peroxynitrite inhibits oxidation of methione residues and leads to inactivation of the enzyme [ 3 ]. | |  |
| 11978481 | glutamine synthetase | glutamine synthetase | 1.0 | there were also significant decreases in glutamine synthetase and creatine kinase activity and alterations in spin labeled synaptosomes consistent with oxidative damage. | |  |
| 14739060 | glutamine synthetase | glutamine synthetase | 1.0 | astrocytes take up glutamate convert it to glutamine through the action of glutamine synthetase an enzyme requiring atp and then release it for uptake by neurons. | |  |
| 14739060 | glutamine synthetase | glutamine synthetase | 1.0 | this cycle can be disrupted by inhibitors of glutamine synthetase an enzyme which can be easily damaged by oxidative stress [ 31 ]. | |  |
| 15896810 | glutamine synthetase | glutamine synthetase | 1.0 | the latter finding that could also be induced by addition of a_amp_#x3b2; to synaptosomes [127] coupled with the reported loss of glutamine synthetase activity in ad brain [127] suggests that glutamate stimulated excitotoxic mechanisms could be important in neurodegeneration in ad. | |  |
| 16043017 | glutamine synthetase | glutamine synthetase | 1.0 | consistent with this notion inclusions in als patients contain b crystallin metallothionein glutamine synthetase and tubulin immunoreactivities [90] . | |  |