HUGO ID Detailed Result 4141


HUGO ID 4141
Symbol GAPDH
Name glyceraldehyde-3-phosphate dehydrogenase
#Occurrence 12
#Paper 6

 


PMID Match String Actual String Score Flanking text Edited by Edit
15896810GAPDHGAPDH1.6demonstrated to stimulate the auto-ADP ribosylation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) GAPDH by reacting with a critical cysteine with resulting binding of 
15896810GAPDHGAPDH1.6resulting binding of NAD to the catalytic cysteine inhibition of GAPDH activity and depression of glycolysis 104 
16242643GAPDHGAPDH0.3(Cycle Cycle threshold method ( Livak and Schmittgen 2001 using GAPDH as internal control once demonstrated that the efficiency for the 
16877542GAPDHGAPDH0.0phox glial fibrillary acidic protein macrophage antigen complex 1 and GAPDH and PCR conditions are presented in Supporting Text 
17496232GAPDHGAPDH0.3of proteins that are regulated by this mechanism (like like GAPDH and that increased denitrosylase activity is a toxic gain of 
11679167glyceraldehyde 3-phosphate dehydrogenaseglyceraldehyde 3 phosphate dehydrogenase1.0the importance of this protective mechanism is illustrated by tdh3p a glyceraldehyde 3 phosphate dehydrogenase isoform.  
11679167glyceraldehyde 3-phosphate dehydrogenaseglyceraldehyde 3 phosphate dehydrogenase1.0it was recently shown that hydrogen peroxide induced protein carbonylation is specific and glyceraldehyde 3 phosphate dehydrogenase and mitochondrial enzymes are the major targets inactivated cabiscol et al. 2000 .  
11679167glyceraldehyde 3-phosphate dehydrogenaseglyceraldehyde 3 phosphate dehydrogenase1.0the inactivation of glyceraldehyde 3 phosphate dehydrogenase may contribute to cellular protection as it increases the levels of glucose 6 phosphate to be used in the pentose phosphate pathway in order to increase the production of nadph see section 3.4 .  
11679167glyceraldehyde 3-phosphate dehydrogenaseglyceraldehyde 3 phosphate dehydrogenase1.0 i the glycolytic flux is inhibited: genes coding for glycolytic enzymes are downregulated and glyceraldehyde 3 phosphate dehydrogenase is oxidatively inactivated see section 2.1 .  
11679167glyceraldehyde 3-phosphate dehydrogenaseglyceraldehyde 3 phosphate dehydrogenase1.0the inhibition of the glycolytic pathway at the step catalysed by glyceraldehyde 3 phosphate dehydrogenase increases the pool of dihydroxyacetone phosphate available for the glycerol cycle godon et al. 1998 .  
15896810glyceraldehyde 3-phosphate dehydrogenaseglyceraldehyde 3 phosphate dehydrogenase1.0no has been demonstrated to stimulate the auto adp ribosylation of glyceraldehyde 3 phosphate dehydrogenase gapdh by reacting with a critical cysteine with resulting binding of nad to the catalytic cysteine inhibition of gapdh activity and depression of glycolysis [104] .  
17584954glyceraldehyde 3-phosphate dehydrogenaseglyceraldehyde 3 phosphate dehydrogenase1.0in fact increased ros production following denervation is mirrored by decreases in surface hydrophobicity and enzymatic activity of glyceraldehyde 3 phosphate dehydrogenase and creatine kinase 64 possibly due to increased oxidative damage 63 .