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| 11050436 | clk 1 | clk 1 | 1.0 | one intriguing example of the link between the ros generating function of the respiratory chain and life span is that provided by the clk 1 protein. | |  |
| 11050436 | clk 1 | clk 1 | 1.0 | the clk 1 protein is responsible for one of the final steps in ubiquinone synthesis so that defective activity results in low endogenous synthesis of ubiquinone for the mitochondrial respiratory chain. | | |
| 11050436 | clk 1 | clk 1 | 1.0 | interference with ubiquinone synthesis in some organisms as demonstrated by the c. elegans clk 1 mutants would be expected to cause a reduction in ubisemiquinone levels a reduction in mitochondrial superoxide production and a subsequent deceleration of shortening and increase in life span[ 40 ]. | | |
| 11679167 | coenzyme q | coenzyme q | 1.0 | the toxicity of lipid hydroperoxides has been associated to a decrease of coenzyme q and glutathione levels. | | |
| 11679167 | coenzyme q | coenzyme q | 1.0 | coenzyme q as well as vitamin e protect cells by reducing lipid peroxyl radicals and therefore by inhibiting the propagation of lipid peroxidation do et al. 1996 . | | |
| 14739060 | coenzyme q | coenzyme q | 1.0 | primary coenzyme q deficiency cause a mitochondrial encephalomyopathy that is responsive to coenzyme q administration [ 44 ]. | | |
| 14739060 | coenzyme q | coenzyme q | 1.0 | clinical trials are underway to test inhibitors of apoptosis such as minocycline [ 17 ] coenzyme q in pd [ 56 ] and many others using so called antioxidants despite disappointing results obtained [ 51 and 52 ]. | | |
| 14739060 | coenzyme q | coenzyme q | 1.0 | then the antioxidant defenses: vitamins a e c selenium food rich in vegetables and fruits and perhaps by using mitochondrial cofactors such as l carnitine r _amp_#x3b1; lipoic acid [ 35 ] riboflavine coenzyme q etc. | | |
| 15896810 | coenzyme q | coenzyme q | 1.0 | the effect of another antioxidant treatment coenzyme q 10 400 mg/day plus vitamin e 2100 iu/day on in vivo cardiac and calf muscle energy metabolism left ventricle hypertrophy lvh and ataxia has been evaluated in ten frda patients [177] after 6 months of | | |