HUGO ID Detailed Result 12022

HUGO ID 12022
Symbol TPT1
Name tumor protein, translationally-controlled 1
#Occurrence 17
#Paper 1

 

PMID Match String Actual String Score Flanking text Edited by Edit
16043017TCTPTCTP2.5These proteins are SOD1 translationally controlled tumor protein (TCTP), TCTP ubiquitin carboxyl-terminal hydrolase-L1 (UCH-L1), UCH-L1 and possibly B-crystallin 
16043017TCTPTCTP2.5decline our current study suggests that oxidative modification of UCH-L1 TCTP SOD1 and possibly B-crystallin may play an important role in 
16043017TCTPTCTP2.5proteins were identified as SOD1 translationally controlled tumor protein (TCTP), TCTP UCH-L1 and B-crystallin 
16043017TCTPTCTP2.5report here that the specific carbonyl levels of human SOD1 TCTP UCH-L1 and possibly B-crystallin are significantly increased in the spinal 
16043017TCTPTCTP2.5levels compared to those of the nontransgenic mice as SOD1 TCTP UCH-L1 and B-crystallin 
16043017TCTPTCTP2.5modified protein in G93A-SOD1 transgenic mice identified by proteomics was TCTP 
16043017TCTPTCTP2.5TCTP processes calcium-binding activity (reviewed reviewed in 55 and has a 
16043017TCTPTCTP2.5Overexpression of TCTP stabilizes microtubules and alters cell morphology 57 
16043017TCTPTCTP2.5Other molecular interactions of TCTP include self-interaction 58 and the interaction with myeloid cell leukemia 
16043017TCTPTCTP2.5TCTP levels are highly regulated in response to various stress conditions 
16043017TCTPTCTP2.5characterization as an antiapoptotic protein 67 these observations suggest that TCTP may exert a cytoprotective function for cells 
16043017TCTPTCTP2.5The current study showed that TCTP was oxidatively modified in the spinal cord of G93A-SOD1 mice 
16043017TCTPTCTP2.5the putative cytoprotective function and the calcium binding affinity of TCTP are impaired in G93A-SOD1 mice because oxidative modification alters the 
16043017TCTPTCTP2.5lymphocytes from ALS patients 70 suggesting that oxidative modification of TCTP may also play an important role in neurotoxicity of G93A-SOD1 
16043017TCTPTCTP2.5remarkable feature of the oxidatively modified proteins (except except for TCTP in G93A-SOD1 transgenic mice is that they are involved in 
16043017TCTPTCTP2.5involves oxidative modification of a Ca 2 regulating protein (TCTP) TCTP and proteins involved in inclusion formation (SOD1, SOD1 UCH-L1 and 
16043017TCTPTCTP2.5proteins impairs protein stability ( B-crystallin Ca 2 binding (TCTP), TCTP protein degradation (UCH-L1), UCH-L1 and antioxidant capacity (SOD1) SOD1