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| 10742195 | aconitase | aconitase | 1.3 | O 2 _amp_#x2212 from reacting with sensitive substrates such as aconitase | |  |
| 11050436 | aconitase | aconitase | 1.3 | For example damage to the cytosolic isoenzyme of aconitase evident after exposure to superoxide results in the release of | |  |
| 11050436 | aconitase | aconitase | 1.3 | The damage to other systems such as mitochondrial aconitase complex I and succinate dehydrogenase which also have important functional | |  |
| 11050436 | aconitase | aconitase | 1.3 | alternative scenario superoxide attacks enzymes (usually usually hydrolyases such as aconitase with 4Fe-4S centres releasing ferrous ions | |  |
| 11679167 | aconitase | aconitase | 1.3 | oxidise 4Fe_amp_#x2013 4S clusters in enzymes such as the mitochondrial aconitase (citric citric acid cycle homoaconitase (lysine lysine biosynthesis and isopropyl | |  |
| 11679167 | aconitase | aconitase | 1.3 | The inactivation of mitochondrial enzymes (aconitase) aconitase results in an impaired respiratory activity that limits the capacity | |  |
| 11679167 | aconitase | aconitase | 1.3 | destroy the 4Fe_amp_#x2013 4S clusters of mitochondrial enzymes (e.g., e.g. aconitase leading to an impaired respiratory activity | |  |
| 11679167 | aconitase | aconitase | 1.3 | a delay in the reversible inactivation of the superoxide-sensitive enzyme aconitase suggesting that the extension of life-span is associated with the | |  |
| 11978481 | aconitase | aconitase | 1.3 | immunochemical probe for oxidative damage it was demonstrated that mitochondrial aconitase was particularly vulnerable to oxidative damage accompanying aging in drosophila | |  |
| 12909279 | aconitase | aconitase | 1.3 | involved in mitochondrial metabolism such as Complex I 53 and aconitase 51 | |  |
| 14739060 | aconitase | aconitase | 1.3 | may prevent the formation of Fe/S Fe S in mitochondrial aconitase and in complex I 20 | |  |
| 15896810 | aconitase | aconitase | 1.6 | mitochondrial respiratory chain complexes I and II/III II III and aconitase activities have been demonstrated in post-mortem cardiac muscle samples from | |  |
| 15896810 | aconitase | aconitase | 1.6 | sulfur cluster present in numerous enzymes including NADH-ubiquinone oxidoreductase cis -aconitase and NADH succinate oxidoreductase 108 | |  |
| 15896810 | aconitase | aconitase | 1.6 | iron metabolism at the post-transcriptional level by interacting with cytosolic aconitase which after binding NO functions as iron responsive binding protein | |  |
| 15896810 | aconitase | aconitase | 1.6 | binding NO functions as iron responsive binding protein diminishing its aconitase activity 109 | |  |
| 16188953 | aconitase | aconitase | 1.6 | 2 O 2 release and by an increase in mitochondrial aconitase activity | |  |
| 16188953 | aconitase | aconitase | 1.6 | Mitochondrial aconitase is reversibly inactivated by superoxide and has therefore been used | |  |
| 16188953 | aconitase | aconitase | 1.6 | against the 23 C-terminal amino acids of aconitase-2 (mitochondrial mitochondrial aconitase from rat (nanoTools; nanoTools Antik_amp_ouml rpertechnik Teningen Germany was used | |  |
| 16188953 | aconitase | aconitase | 1.6 | 30 mg/kg) mg kg results in an increase in mitochondrial aconitase activity in vivo indicating a reduction of the superoxide steady-state | |  |
| 16188953 | aconitase | aconitase | 1.6 | 12 h after the last treatment the increase in mitochondrial aconitase might result from total brain concentrations within the same order | |  |
| 16188953 | aconitase | aconitase | 1.6 | PPX causes a slight but not significant increase in total aconitase activity in 1-methyl-4-phenylpyridinium-treated SHSY-5Y cells | |  |
| 16188953 | aconitase | aconitase | 1.6 | specific endpoints such as modification of mitochondrial proteins or mitochondrial aconitase activity | |  |
| 16188953 | aconitase | aconitase | 1.6 | Activity (A) A and expression (B) B of mitochondrial aconitase after treatment of C57BL/6 C57BL 6 mice with PPX (2 | |  |
| 16188953 | aconitase | aconitase | 1.6 | were isolated after PPX treatment of mice to determine mitochondrial aconitase activity an indicator for steady-state levels of superoxide (Tarpey Tarpey | |  |
| 16188953 | aconitase | aconitase | 1.6 | days (2 2 x 30 mg/kg) mg kg increased mitochondrial aconitase activity by 42% to 67 _amp_#177 16 mU/mg mU mg | |  |
| 16188953 | aconitase | aconitase | 1.6 | This was not due to altered expression of mitochondrial aconitase because protein levels were not affected by the PPX treatment | |  |
| 16227974 | aconitase | aconitase | 2.1 | Studies with the mitochondrial protein aconitase have demonstrated that low levels of ROS caused mild oxidation | |  |
| 16227974 | aconitase | aconitase | 2.1 | oxidation and stimulated degradation whereas higher levels of ROS caused aconitase to aggregate and become more resistant to proteasomal degradation 20 | |  |
| 16227974 | aconitase | aconitase | 2.1 | the activity of a set of metabolic enzymes such as aconitase and components of mitochondrial complex I that contain Fe-S clusters | |  |
| 16188953 | aconitase 2 | aconitase 2 | 1.0 | detoxification of reactive oxygen species ros by pramipexole is shown in vitro and in vivo by evaluating mitochondrial ros release and aconitase 2 activity respectively. | |  |
| 16188953 | aconitase 2, mitochondrial | aconitase 2 mitochondrial | 1.0 | additionally a monoclonal antibody raised against the 23 c terminal amino acids of aconitase 2 mitochondrial aconitase from rat nanotools; antik_amp_ouml;rpertechnik teningen germany was used to study the expression of the protein in mitochondria. | |  |
| 16188953 | aconitase 2 | aconitase 2 | 1.0 | afterward aconitase 2 expression was analyzed by a standard western blot protocol by probing the used nitrocellulose membranes with the anti aconitase 2 antibody 2 microg/ml using an enhanced chemiluminescence detection system applied biosystems . | |  |