HUGO ID Detailed Result 11506


HUGO ID 11506
Symbol SYP
Name synaptophysin
#Occurrence 8
#Paper 2

 


PMID Match String Actual String Score Flanking text Edited by Edit
11562447synaptophysinsynaptophysin1.0onoo dependent changes in several presynaptic proteins chat synaptophysin vamp/synaptobrevin actin tubulin present in t. marmorata synaptosomes and synaptic vesicles were examined and showed examples of nitration of tyrosines and covalent oligomerization.  
11562447synaptophysinsynaptophysin1.0polyclonal antibody against t. marmorata synaptophysin and monoclonal antibodies against vamp/synaptobrevin and tubulin were developed and characterized in the laboratory by dr. nicolas morel laboratoire de neurobiologie cellulaire et moleculaire cnrs gi 
11562447synaptophysinsynaptophysin1.0moreover we were able to define affected residues by taking advantage of a specific antibody raised against a well conserved sequence gyqpnygq q of the t. marmorata synaptophysin cowan et al. 1990 .  
11562447synaptophysinsynaptophysin1.0 can affect numerous proteins at the presynaptic side of a neuromuscular junction in several subcellular compartments; these include choline transporter at the plasma membrane chat in the cytosol and synaptophysin tubulin or actin at the periphery of synaptic vesicles.  
11562447synaptophysinsynaptophysin1.0arrows show actin 1/200 c tubulin 1/1000 d synaptophysin 1/2500 e and vamp/synaptobrevin 1/25 a .  
11562447synaptophysinsynaptophysin1.0synaptophysin an integral vesicular 38 kda glycoprotein was detected in the controls fig 5 e as a doublet using an antibody directed against the c terminal epitope gyqpnygq q cowan et al. 1990 ; n morel personal c 
11562447synaptophysinsynaptophysin1.0 dr. pierre potier in whose laboratories this work was performed for continuous support; dr. nicolas morel for help on immunological studies and the kind gift of antibodies against vamp/synaptobrevin synaptophysin and tubulin; dr. fran_amp_ccedil;ois marie meunier for sequence alignments; dr. seana o'regan for expertise in choline uptake mechanisms and critical reading; and dr. michael spedding and dr. esther  
14648077synaptophysinsynaptophysin1.0or normal cytosolic constitutive proteins including tubulin and tau protein as well as neuron specific constitutive proteins containing phosphorylated neurofilament proteins nfp nonphosphorylated nfp synaptophysin and neuron specific enolase [ 13 17 18 ]; this results in partial impairment of the maintenance of cell metabolism [ 13 17 18 ].