HUGO ID Detailed Result 10939


HUGO ID 10939
Symbol SLC1A1
Name solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
#Occurrence 10
#Paper 1

 


PMID Match String Actual String Score Flanking text Edited by Edit
9745361EAAC1EAAC13.0of at least three transporter subtypes (GLT1, GLT1 GLAST and EAAC1 and shown to regulate transport rate via thiol-disulphide redox interconversion 
9745361EAAC1EAAC13.0have now been identified GLAST (EAAT1), EAAT1 GLT1 (EAAT2), EAAT2 EAAC1 (EAAT3), EAAT3 EAAT4 and EAAT5 (Refs Refs 1 2 3 
9745361EAAT3EAAT32.5been identified GLAST (EAAT1), EAAT1 GLT1 (EAAT2), EAAT2 EAAC1 (EAAT3), EAAT3 EAAT4 and EAAT5 (Refs Refs 1 2 3 4 5 
9745361EAAC1EAAC13.0In the brain the EAAC1 protein and mRNA are found in neurones 15 16 where 
9745361EAAC1EAAC13.0EAAC1 is not restricted to glutamatergic neurones and has now also 
9745361EAAC1EAAC1-knockout2.5In contrast EAAC1-knockout mice develop dicarboxylic aminoaciduria and no sign of neurodegeneration during 
9745361EAAC1EAAC13.0Indeed the transport activities of GLT1 EAAC1 and GLAST are equally inhibited by oxidants via a direct 
9745361EAAC1EAAC13.0EAAC1 GLT1 and GLAST exhibit redox-sensing properties 
9745361EAAC1EAAC13.0EAAC1 GLAST GLT1 EAAT4 and EAAT5 carry different cysteine residues in 
9745361EAAC1EAAC13.0Glutamate transporters located in the postsynaptic compartment (e.g e.g EAAC1 or EAAT4 have an increased chance of exposure to noxious